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DSP-1053

DSP-1053 Structure
DSP-1053 structure
CAS No.
1176326-76-3
Chemical Name:
DSP-1053
Synonyms
DSP-1053;4H-1-Benzopyran-4-one, 6-[2-[4-[[4-bromo-3-(2-methoxyethoxy)phenyl]methyl]-1-piperidinyl]ethyl]-2,3-dihydro-
CBNumber:
CB84667845
Molecular Formula:
C26H32BrNO4
Molecular Weight:
502.44
MDL Number:
MFCD31813640
MOL File:
1176326-76-3.mol
Last updated:2024-07-02 08:55:36
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DSP-1053 Properties

Boiling point 610.7±55.0 °C(Predicted)
Density 1.294±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 100 mg/mL (199.03 mM; Need ultrasonic)
form Solid
pka 9.06±0.10(Predicted)
color Off-white to light yellow

DSP-1053 Chemical Properties,Uses,Production

Biological Activity

DSP-1053, a benzylpiperidine derivative, is a potent Serotonin Transporter (SERT) inhibitor with a Ki of 1.02 nM. DSP-1053 shows partial 5-HT1A receptor agonistic activity with a Ki of 5.05 nM. DSP-1053 has antidepressant activity[1].

References

[1]. Yoshinaga H, et al. Discovery of DSP-1053, a novel benzylpiperidine derivative with potent serotonin transporter inhibitory activity and partial 5-HT1A receptor agonistic activity. Bioorg Med Chem. 2018 May 1;26(8):1614-1627.

DSP-1053 Preparation Products And Raw materials

Raw materials

Preparation Products

DSP-1053 Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Guangzhou Younan Technology Co., Ltd 020-020-82000279 18988968278 sales@ubiochem.com China 4297 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29778 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 021-59167510 18117107507 vip@med-life.cn China 4997 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19696 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Guangzhou Younan Technology Co., Ltd 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 58
TargetMol Chemicals Inc. 58
DSP-1053 4H-1-Benzopyran-4-one, 6-[2-[4-[[4-bromo-3-(2-methoxyethoxy)phenyl]methyl]-1-piperidinyl]ethyl]-2,3-dihydro- 1176326-76-3