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JAS239
- CAS No.
- 1630288-74-2
- Chemical Name:
- JAS239
- Synonyms
- JAS239;JAS239 (JAS 239
- CBNumber:
- CB84668064
- Molecular Formula:
- C31H37ClN2O2
- Molecular Weight:
- 505.1
- MDL Number:
- MOL File:
- 1630288-74-2.mol
Last updated:2024-10-23 13:36:13
JAS239 Chemical Properties,Uses,Production
Description
JAS239 is a novel carbocyanine dye that binds and competitively inhibits choline kinase (ChoK) intracellularly. JAS239 attenuated choline phosphorylation and viability in a panel of human breast cancer cell lines. Antibody blockade prevented cellular retention of JAS239 indicating direct interaction with ChoKα independent of the choline transporters and catabolic choline pathways. In mice bearing orthotopic MCF7 breast xenografts, optical imaging with JAS239 distinguished tumors overexpressing ChoKα from their empty vector counterparts and delineated tumor margins.
JAS239 Preparation Products And Raw materials
Raw materials
Preparation Products
JAS239 Suppliers
Global( 8)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19863 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24648 | 58 |
| Pushan Industry (Shaanxi) Co., Ltd. | 029-81310890 13571859809 | info@pushanshiye.com | China | 10007 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 13417589054 | trendseenbio@gmail.com | China | 9470 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | cindy.huang@synzest.com | China | 12005 | 58 |
JAS239
JAS239
(JAS 239
1630288-74-2