1,4-DITHIOTHREITOL-D10
- CAS No.
- 302912-05-6
- Chemical Name:
- 1,4-DITHIOTHREITOL-D10
- Synonyms
- DL-Dithiothreitol-d??;dl-dithiothreitol-d10;cleland's reagent-d10;1,4-DITHIOTHREITOL-D10;DL-1,4-DITHIOTHREITOL (D10);1,4-DITHIOTHREITOL-D10, 98 ATOM % D;
DL -Dithiothreitol-d10;DL-Dithiothreitol-d10 98 atom % D, 98% (CP);1,1,2,3,4,4-hexadeuterio-2,3-dideuteriooxy-1,4-bis(deuteriosulfanyl)butane
- CBNumber:
- CB8469078
- Molecular Formula:
- C4D10O2S2
- Molecular Weight:
- 164.31
- MDL Number:
- MFCD00274655
- MOL File:
- 302912-05-6.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
1,4-DITHIOTHREITOL-D10 price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 485535 | DL-Dithiothreitol-d10 98 atom % D, 98% (CP) | 302912-05-6 | 500mg | $1210 | 2024-03-01 | Buy |
| American Custom Chemicals Corporation | RDL0009182 | (+/-)-1,4-DITHIOTHREITOL-D10 95.00% | 302912-05-6 | 5MG | $501.77 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | D17073 | (+/-)-1,4-Dithiothreitol-d10 98% | 302912-05-6 | 0.1g | $810 | 2021-12-16 | Buy |
1,4-DITHIOTHREITOL-D10 Chemical Properties,Uses,Production
Uses
DL-dithiothreitol-d10 is the deuterated form of DL-dithiothreitol. DL-dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. When DL-dithiothreitol is oxidized, it forms a stable six-membered ring with an internal disulfide bond[1][2].
References
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Yao H, et al. Establishment of disulfidptosis-related LncRNA signature as biomarkers in colon adenocarcinoma[J]. Cancer Cell International, 2024, 24(1): 183. DOI:10.1186/s12935-024-03374-6
1,4-DITHIOTHREITOL-D10 Preparation Products And Raw materials
Raw materials
Preparation Products
1,4-DITHIOTHREITOL-D10 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Clearsynth Labs Limited | +91-22-26355700 | info@clearsynth.com | India | 9679 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51456 | 80 |
| Nanjing Haolv Biotechnology Co.,Ltd | 025-84622273 17361806303 | kexin.zhou@haolvbiotech.com | China | 3020 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44812 | 58 |
| Changzhou Bojia Biomedical Technology Co., Ltd. | 2122619822 | czbjpharma@126.com | China | 18478 | 58 |
| Reer Technology (Shanghai) Co., LTD | 021-64400900 15800436310 | bessey@reertech.com | China | 4105 | 58 |
| Shanghai Aladdin Biochemical Technology Co.,Ltd. | 400-6206333 1316706386 | anhua.mao@aladdin-e.com | China | 48458 | 58 |
| Merck KGaA | (+86) 21 2033 8288 | sigmaname@qq.com | CHINA | 292394 | 58 |