ChemicalBook >> CAS DataBase List >>4-((2-(2-(2-aminoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
4-((2-(2-(2-aminoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
- CAS No.
- 2093416-32-9
- Chemical Name:
- 4-((2-(2-(2-aminoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
- Synonyms
- Thalidomide-PEG2-C2-NH2;Thalidomide-NH-PEG2-C2-NH2;Thalidomide-4-NH-PEG2-C2-NH2;4-((2-(2-(2-aminoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione;1H-Isoindole-1,3(2H)-dione, 4-[[2-[2-(2-aminoethoxy)ethoxy]ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-;4-({2-[2-(2-aminoethoxy)ethoxy]ethyl}amino)-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
- CBNumber:
- CB84849371
- Molecular Formula:
- C19H24N4O6
- Molecular Weight:
- 404.42
- MDL Number:
- MFCD32263424
- MOL File:
- 2093416-32-9.mol
Last updated:2023-02-23 14:24:01
4-((2-(2-(2-aminoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
DC Chemicals | 027582 | Thalidomide-PEG2-C2-NH2 | 2093416-32-9 | 002 | $850 | 2021-12-16 | Buy |
A1 Biochem Labs | A1-26739 | 4-((2-(2-(2-Aminoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 95% | 2093416-32-9 | 1g | $1200 | 2021-12-16 | Buy |
DC Chemicals | DC50056 | Thalidomide-PEG2-C2-NH2 | 2093416-32-9 | 1g | $1700 | 2021-12-16 | Buy |
4-((2-(2-(2-aminoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Chemical Properties,Uses,Production
Biological Activity
Thalidomide-PEG2-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References
[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.
4-((2-(2-(2-aminoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Preparation Products And Raw materials
Raw materials
Preparation Products
4-((2-(2-(2-aminoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Suppliers
Global( 19)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8647 | 58 |
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 10991 | 58 |
Suzhou Highfine Biotech Co., Ltd | 0512-69209928 18306209933 | joyce@highfine.com | China | 498 | 75 |
Daicel Chiral Technologies (China)CO.,LTD | 021-50460086-9 15921403865 | han_yajun@dctc.daicel.com | China | 7178 | 65 |
Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7887 | 56 |
Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9943 | 58 |
Jilin Province Woda Biotechnology Co., Ltd. | 13504435624 | 1927928688@qq.com | China | 1382 | 58 |
DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9412 | 58 |
Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD | 025-86755008 17751752005 | hszhang@bestfluorodrug.com | China | 2358 | 58 |
2093416-32-9(4-((2-(2-(2-aminoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione)Related Search:
4-((2-(2-(2-aminoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Thalidomide-NH-PEG2-C2-NH2
1H-Isoindole-1,3(2H)-dione, 4-[[2-[2-(2-aminoethoxy)ethoxy]ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-
Thalidomide-PEG2-C2-NH2
Thalidomide-4-NH-PEG2-C2-NH2
4-({2-[2-(2-aminoethoxy)ethoxy]ethyl}amino)-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
2093416-32-9