4-Hydroxy-2-butanone
- CAS No.
- 590-90-9
- Chemical Name:
- 4-Hydroxy-2-butanone
- Synonyms
- 4-hydroxybutan-2-one;CH3C(O)CH2CH2OH;Methylolacetone;2-Butanone, 4-hydroxy-;3-Oxobutanol;Butanone glycol;3-Ketobutan-1-ol;H**4-HYDROXY-2-BUTANONE;ketobutanol;Hydroxy-2-butan
- CBNumber:
- CB8493505
- Molecular Formula:
- C4H8O2
- Molecular Weight:
- 88.11
- MDL Number:
- MFCD00059005
- MOL File:
- 590-90-9.mol
- MSDS File:
- SDS
Melting point | 15°C (estimate) |
---|---|
Boiling point | 73-76 °C/12 mmHg (lit.) |
Density | 1.023 g/mL at 25 °C (lit.) |
refractive index | 1.430 |
Flash point | 91°F |
storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
solubility | Chloroform, Methanol (Slightly) |
form | Oil |
pka | 14.43±0.10(Predicted) |
color | Clear Colourless |
Water Solubility | Miscible with water, alcohol, ethanol and ether. |
BRN | 1737666 |
LogP | -1.209 at 25℃ |
CAS DataBase Reference | 590-90-9(CAS DataBase Reference) |
FDA UNII | TCM0BJ44MF |
NIST Chemistry Reference | 4-Hydroxy-2-butanone(590-90-9) |
EPA Substance Registry System | 2-Butanone, 4-hydroxy- (590-90-9) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() GHS02,GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H227-H315-H319-H335-H226 | |||||||||
Precautionary statements | P210e-P261-P280a-P305+P351+P338-P405-P501a | |||||||||
Risk Statements | 10 | |||||||||
Safety Statements | 16-24/25 | |||||||||
RIDADR | UN 1993 | |||||||||
WGK Germany | 3 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29144000 | |||||||||
NFPA 704 |
|
4-Hydroxy-2-butanone price More Price(21)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 252557 | 4-Hydroxy-2-butanone 95% | 590-90-9 | 100g | $176 | 2024-03-01 | Buy |
TCI Chemical | H0584 | 4-Hydroxy-2-butanone >95.0%(GC) | 590-90-9 | 25mL | $38 | 2024-03-01 | Buy |
TCI Chemical | H0584 | 4-Hydroxy-2-butanone >95.0%(GC) | 590-90-9 | 100mL | $111 | 2024-03-01 | Buy |
Alfa Aesar | L11456 | 4-Hydroxy-2-butanone, 95% | 590-90-9 | 25g | $59.1 | 2024-03-01 | Buy |
Alfa Aesar | L11456 | 4-Hydroxy-2-butanone, 95% | 590-90-9 | 100g | $150 | 2024-03-01 | Buy |
4-Hydroxy-2-butanone Chemical Properties,Uses,Production
Chemical Properties
Colourless to pale yellow liquid
Uses
4-Hydroxy-2-butanone is used in the preparation of fused benzazepine molecules as selective D3 receptor antagonists with pharmaceutical activity. It is also used in the preparation of verrucarin and mevalonic acid lactone. Further, it is used to prepare 3-buten-2-one through dehydration over an anatase titanium dioxide catalyst. It is also employed in the preparation of 4-methyl-5-hydroxymethylthiazole, (±)-lineatin and beta-hydroxylactones.
Definition
ChEBI: A beta-hydroxy ketone that is butan-2-one substituted by a hydroxy group at position 4.
Application
4-Hydroxy-2-butanone has been used in the synthesis of:
- 3-buten-2-one via dehydration over anatase-TiO2 catalyst
- 4-methyl-5-hydroxymethylthiazole
- (±)-lineatin
- mevalonic acid lactone
- verrucarin
- β-hydroxylactones
General Description
4-Hydroxy-2-butanone is an important pharmaceutical intermediate. Gas phase reaction of the OH radicals with 4-hydroxy-2-butanone has been investigated by absolute rate method.
4-Hydroxy-2-butanone Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1of2
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12449 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5869 | 58 |
Anhui Yiao New Material Technology Co., Ltd | +86-18033737140 +86-17354101231 | sales1@hbganmiao.com | China | 253 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20294 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21668 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29892 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
View Lastest Price from 4-Hydroxy-2-butanone manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
![]() |
2024-08-21 | 4-Hydroxy-2-butanone
590-90-9
|
US $5.00-2.00 / KG | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
![]() |
2024-08-15 | 4-Hydroxy-2-butanone
590-90-9
|
US $0.00-0.00 / kg | 1kg | 95%+ | 30MT/Month | Hebei Yanxi Chemical Co., Ltd. | |
![]() |
2024-06-11 | 4-Hydroxy-2-butanone
590-90-9
|
US $0.00 / KG | 1KG | 99% | 1 ton | Anhui Yiao New Material Technology Co., Ltd |
-
- 4-Hydroxy-2-butanone
590-90-9
- US $5.00-2.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- 4-Hydroxy-2-butanone
590-90-9
- US $0.00-0.00 / kg
- 95%+
- Hebei Yanxi Chemical Co., Ltd.
-
- 4-Hydroxy-2-butanone
590-90-9
- US $0.00 / KG
- 99%
- Anhui Yiao New Material Technology Co., Ltd