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P405
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NFPA 704
2
2
0
4-하이드록시-2-부타논 C화학적 특성, 용도, 생산
화학적 성질
Colourless to pale yellow liquid
용도
4-Hydroxy-2-butanone is used in the preparation of fused benzazepine molecules as selective D3 receptor antagonists with pharmaceutical activity. It is also used in the preparation of verrucarin and mevalonic acid lactone. Further, it is used to prepare 3-buten-2-one through dehydration over an anatase titanium dioxide catalyst. It is also employed in the preparation of 4-methyl-5-hydroxymethylthiazole, (±)-lineatin and beta-hydroxylactones.
정의
ChEBI: A beta-hydroxy ketone that is butan-2-one substituted by a hydroxy group at position 4.
주요 응용
4-Hydroxy-2-butanone has been used in the synthesis of:
3-buten-2-one via dehydration over anatase-TiO2 catalyst
4-methyl-5-hydroxymethylthiazole
(±)-lineatin
mevalonic acid lactone
verrucarin
β-hydroxylactones
일반 설명
4-Hydroxy-2-butanone is an important pharmaceutical intermediate. Gas phase reaction of the OH radicals with 4-hydroxy-2-butanone has been investigated by absolute rate method.
