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4-Hydroxy-2-butanone

CAS No.
590-90-9
Chemical Name:
4-Hydroxy-2-butanone
Synonyms
4-hydroxybutan-2-one;CH3C(O)CH2CH2OH;Methylolacetone;2-Butanone, 4-hydroxy-;3-Oxobutanol;Butanone glycol;3-Ketobutan-1-ol;H**4-HYDROXY-2-BUTANONE;ketobutanol;Hydroxy-2-butan
CBNumber:
CB8493505
Molecular Formula:
C4H8O2
Molecular Weight:
88.11
MDL Number:
MFCD00059005
MOL File:
590-90-9.mol
MSDS File:
SDS
Last updated:2024-10-25 16:21:11

4-Hydroxy-2-butanone Properties

Melting point 15°C (estimate)
Boiling point 73-76 °C/12 mmHg (lit.)
Density 1.023 g/mL at 25 °C (lit.)
refractive index 1.430
Flash point 91°F
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Chloroform, Methanol (Slightly)
form Oil
pka 14.43±0.10(Predicted)
color Clear Colourless
Water Solubility Miscible with water, alcohol, ethanol and ether.
BRN 1737666
LogP -1.209 at 25℃
CAS DataBase Reference 590-90-9(CAS DataBase Reference)
FDA UNII TCM0BJ44MF
NIST Chemistry Reference 4-Hydroxy-2-butanone(590-90-9)
EPA Substance Registry System 2-Butanone, 4-hydroxy- (590-90-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Warning
Hazard statements  H227-H315-H319-H335-H226
Precautionary statements  P210e-P261-P280a-P305+P351+P338-P405-P501a
Risk Statements  10
Safety Statements  16-24/25
RIDADR  UN 1993
WGK Germany  3
TSCA  Yes
HS Code  29144000
NFPA 704
2
2 0

4-Hydroxy-2-butanone price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 252557 4-Hydroxy-2-butanone 95% 590-90-9 100g $176 2024-03-01 Buy
TCI Chemical H0584 4-Hydroxy-2-butanone >95.0%(GC) 590-90-9 25mL $38 2024-03-01 Buy
TCI Chemical H0584 4-Hydroxy-2-butanone >95.0%(GC) 590-90-9 100mL $111 2024-03-01 Buy
Alfa Aesar L11456 4-Hydroxy-2-butanone, 95% 590-90-9 25g $59.1 2024-03-01 Buy
Alfa Aesar L11456 4-Hydroxy-2-butanone, 95% 590-90-9 100g $150 2024-03-01 Buy
Product number Packaging Price Buy
252557 100g $176 Buy
H0584 25mL $38 Buy
H0584 100mL $111 Buy
L11456 25g $59.1 Buy
L11456 100g $150 Buy

4-Hydroxy-2-butanone Chemical Properties,Uses,Production

Chemical Properties

Colourless to pale yellow liquid

Uses

4-Hydroxy-2-butanone is used in the preparation of fused benzazepine molecules as selective D3 receptor antagonists with pharmaceutical activity. It is also used in the preparation of verrucarin and mevalonic acid lactone. Further, it is used to prepare 3-buten-2-one through dehydration over an anatase titanium dioxide catalyst. It is also employed in the preparation of 4-methyl-5-hydroxymethylthiazole, (±)-lineatin and beta-hydroxylactones.

Definition

ChEBI: A beta-hydroxy ketone that is butan-2-one substituted by a hydroxy group at position 4.

Application

4-Hydroxy-2-butanone has been used in the synthesis of:

  • 3-buten-2-one via dehydration over anatase-TiO2 catalyst
  • 4-methyl-5-hydroxymethylthiazole
  • (±)-lineatin
  • mevalonic acid lactone
  • verrucarin
  • β-hydroxylactones

General Description

4-Hydroxy-2-butanone is an important pharmaceutical intermediate. Gas phase reaction of the OH radicals with 4-hydroxy-2-butanone has been investigated by absolute rate method.

50-00-0
67-64-1
590-90-9
Synthesis of 4-Hydroxy-2-butanone from Formaldehyde and Acetone
Global( 344)Suppliers
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Hebei Mojin Biotechnology Co., Ltd
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Hebei Chuanghai Biotechnology Co,.LTD
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View Lastest Price from 4-Hydroxy-2-butanone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Hydroxy-2-butanone pictures 2024-10-25 4-Hydroxy-2-butanone
590-90-9
US $0.00-0.00 / kg 1kg 95%+ 30MT/Month Hebei Yanxi Chemical Co., Ltd.
4-Hydroxy-2-butanone pictures 2024-10-25 4-Hydroxy-2-butanone
590-90-9
US $30.00-10.00 / KG 50KG 99% 500000kg Hebei Weibang Biotechnology Co., Ltd
4-Hydroxy-2-butanone pictures 2024-10-11 4-Hydroxy-2-butanone
590-90-9
US $5.00-2.00 / KG 1KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
2-Butanone,4-hydroxy- 3-Oxo-1-butanol 4-Butanol-2-one 4-hydroxy-2-butanon Monomethylolacetone 4-HYDROXY-2-BUTANONE 2-HYDROXYETHYL METHYL KETONE 4-Hydroxy-2-butanone,95% ketobutanol 1-Hydroxy-3-butanone Hydroxy-2-butan 4-Hydroxy-2-butanone , 95.0%(GC) 4-hydrxy-2-butone 4-Hydroxy-2-butanone > 3-Ketobutan-1-ol CH3C(O)CH2CH2OH Methylolacetone 4-hydroxybutan-2-one H**4-HYDROXY-2-BUTANONE Butanone glycol 2-Butanone, 4-hydroxy- 3-Oxobutanol 590-90-9 HOCH2CH2COCH3 KETONE Organic Building Blocks Ketones Carbonyl Compounds C3 to C6 Building Blocks in-stock straight chain compounds ketone 1 bc0001 590-90-9 john's