ChemicalBook >> CAS DataBase List >>Tazofelone, LY-213829
Tazofelone, LY-213829
- CAS No.
- 107902-67-0
- Chemical Name:
- Tazofelone, LY-213829
- Synonyms
- LY-213829;Tazofelone, LY-213829;5-(3,5-Di-tert-butyl-4-hydroxybenzyl)thiazolidin-4-one;4-Thiazolidinone, 5-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]-;Inhibitor,LY 213829,Tazofelone,CYP3A,inflammatory bowel disease,inhibit,Cyclooxygenase,COX,LY213829
- CBNumber:
- CB85855432
- Molecular Formula:
- C18H27NO2S
- Molecular Weight:
- 321.48
- MDL Number:
- MFCD00868113
- MOL File:
- 107902-67-0.mol
Last updated:2024-07-02 08:55:37
| storage temp. | Store at -20°C |
|---|---|
| solubility | DMSO : 100 mg/mL (311.06 mM; Need ultrasonic) |
| form | Solid |
| color | White to off-white |
| FDA UNII | VH2I1JN8Q1 |
Tazofelone, LY-213829 Chemical Properties,Uses,Production
Biological Activity
Tazofelone (LY 213829) is a cyclooxygenase-II (COX-II) inhibitor. Tazofelone transform into sulfoxide and quinol metabolites is primarily mediated by CYP3A. Tazofelone can be used for the research of inflammatory bowel disease[1][2].
References
[1]. Leopold Franz Goetze,et al. Cox- ii inhibitors for improving reproductive success in a female animal. Patent: WO2007129169 A2. [2]. Surapaneni SS, et al. In vitro biotransformation and identification of human cytochrome P450 isozyme-dependent metabolism of tazofelone. Drug Metab Dispos. 1997 Dec;25(12):1383-8.
Tazofelone, LY-213829 Preparation Products And Raw materials
Raw materials
Preparation Products
Tazofelone, LY-213829 Suppliers
Global( 10)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 3717 | 55 |
| Bide Pharmatech Ltd. | 400-1647117 15221909166 | product02@bidepharm.com | China | 63720 | 58 |
| Changzhou Bojia Biomedical Technology Co., Ltd. | 2122619822 | czbjpharma@126.com | China | 18488 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24017 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 4399 | 58 |
| Shanghai Jieshikai Biotechnology Co. , Ltd. | 021-57520305 15221441005 | guojianing@jskchem.com | China | 49242 | 58 |
| Shanghai Aladdin Biochemical Technology Co.,Ltd. | +86-18521732826 | market@aladdin-e.com | China | 48467 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9155 | 58 |
Tazofelone, LY-213829
4-Thiazolidinone, 5-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]-
LY-213829
5-(3,5-Di-tert-butyl-4-hydroxybenzyl)thiazolidin-4-one
Inhibitor,LY 213829,Tazofelone,CYP3A,inflammatory bowel disease,inhibit,Cyclooxygenase,COX,LY213829
107902-67-0