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Octyl gallate

CAS No.
1034-01-1
Chemical Name:
Octyl gallate
Synonyms
Progallin O;OCTYL GALLATE;N-OCTYL GALLATE;Stabilizer GA-8;OCTYLGALLATE(RG);Gallic acid octyl;n-OctylGallate>Octyl gallate CRS;n-Octyl gallate, 98+%;GALLIC ACID OCTYL ESTER
CBNumber:
CB8704027
Molecular Formula:
C15H22O5
Molecular Weight:
282.33
MDL Number:
MFCD00002197
MOL File:
1034-01-1.mol
MSDS File:
SDS
Last updated:2024-11-17 16:00:36

Octyl gallate Properties

Melting point 101-104 °C(lit.)
Boiling point 262.5°C (estimate)
Density 1.0984 (rough estimate)
refractive index 1.6200 (estimate)
storage temp. Store below +30°C.
solubility soluble2.5%, clear, colorless (AcOH (MEOH))
form Solid
pka 7.94±0.25(Predicted)
color White to Off-White
Water Solubility 20mg/L(29.99 ºC)
BRN 2132305
LogP 3.660
Substances Added to Food (formerly EAFUS) OCTYL GALLATE
CAS DataBase Reference 1034-01-1(CAS DataBase Reference)
EWG's Food Scores 1-2
FDA UNII 079IIA2811
EPA Substance Registry System Benzoic acid, 3,4,5-trihydroxy-, octyl ester (1034-01-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H317
Precautionary statements  P280-P301+P312+P330-P302+P352
Hazard Codes  Xn
Risk Statements  22-43
Safety Statements  24-37
WGK Germany  1
RTECS  LW8225000
TSCA  Yes
HS Code  2918 29 00
Toxicity LD50 orally in Rabbit: 1960 mg/kg
NFPA 704
1
2 0

Octyl gallate price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 48700 Octyl gallate antioxidant, ≥99.0% (HPLC) 1034-01-1 50g $137 2024-03-01 Buy
Sigma-Aldrich PHR3511 Octyl Gallate certified reference material, pharmaceutical secondary standard 1034-01-1 500MG $243 2024-03-01 Buy
Sigma-Aldrich 48700 Octyl gallate antioxidant, ≥99.0% (HPLC) 1034-01-1 250g $605 2024-03-01 Buy
Sigma-Aldrich 06717 Octyl gallate analytical standard 1034-01-1 500mg $102 2022-05-15 Buy
TCI Chemical G0206 n-Octyl Gallate >98.0%(T) 1034-01-1 25g $64 2024-03-01 Buy
Product number Packaging Price Buy
48700 50g $137 Buy
PHR3511 500MG $243 Buy
48700 250g $605 Buy
06717 500mg $102 Buy
G0206 25g $64 Buy

Octyl gallate Chemical Properties,Uses,Production

Description

Octyl gallate is the ester formed by 1-octanol and gallic acid. It can be used as an antioxidant and preservative to be supplemented to the food. It has been demonstrated to be an effective fungicide being capable of inhibiting the growth of S. cerevisiae and Z. bailii as it can inhibit the fluidity of the cell membrane through acting as a nonionic surface-active agent. It is also capable of killing both DNA and RNA viruses with a relatively moderate cytotoxicity. For example, it has the potential to treat influenza. Octyl gallate also has certain bactericidal activity, being capable of treating the infections associated with enterococci.

References

[1]Ken-Ichi, Fujita, and K. Isao. "Antifungal activity of octyl gallate. " International Journal of Food Microbiology 79.3(2002):1
[2]Gutiérrez-Fernández, J, et al. "Antimicrobial activity of binary combinations of natural and synthetic phenolic antioxidants against Enterococcus faecalis. " Journal of Dairy Science 96.8(2013):4912-20.93.
[3] Yamasaki, H, et al. "Antiviral effect of octyl gallate against influenza and other RNA viruses. " International Journal of Molecular Medicine 19.4(2007): 685-688.

Description

During the 1940s, propyl gallate and several other alkyl gallates were allowed for use in foods in a number of countries. Since gallic acid contains three phenolic hydroxyl groups, it is a rather potent antioxidant; however, the propyl ester has a significant degree of water solubility. As a consequence, propyl gallate tends to partition into any water phase which may be present and to complex with iron salts to give bluish black colors. Also, its relatively poor resistance to heat degradation makes it ineffective for baking and frying applications. The higher alkyl gallates (butyl and octyl) are more fat soluble.

Chemical Properties

White powder

Uses

Used in treatment of alcohol dependence.

Uses

Octyl gallate is an antioxidant for use in cosmetic and pharmaceutical products and in food products, such as margarine and peanut butter.

Uses

Octyl gallate is an antioxidant that is used as a preservation agent in a wide variety of foods, oils, and cosmetics.

Definition

ChEBI: A gallate ester obtained by condensation of the carboxy group of gallic acid with the hydroxy group of octanol.

General Description

Octyl gallate is an ester of gallic acid which is generally used as an antioxidant in food and pharmaceutical industries. It can act against the oxidative damage caused by reactive oxygen species (ROS) in the form of hydroxyl radicals or hydrogen peroxides, and reactive sulfur species (RSS)

Contact allergens

Octyl gallate, a gallate ester (E 311), is an antioxidant added to food and cosmetics to prevent oxidation of unsaturated fatty acids. Cases were sparsely reported in food industry or from lipsticks. Patch tests are frequently irritant.

Safety Profile

A poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition it emits acrid smoke and irritating fumes.

111-87-5
831-61-8
1034-01-1
Synthesis of Octyl gallate from 1-Octanol and Ethyl gallate

Octyl gallate Preparation Products And Raw materials

Global( 347)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd
+86-29-81148696 +86-15536356810 1022@dideu.com China 3882 58
Hebei Saisier Technology Co., LTD
+86-18400010335 +86-18034520335 admin@hbsaisier.cn China 1015 58
Hebei Zhuanglai Chemical Trading Co.,Ltd
+8613343047651 admin@zlchemi.com China 3002 58
Hebei Longbang Technology Co., LTD
+86-18633929156 +86-18633929156 admin@hblongbang.com China 941 58
HebeiShuoshengImportandExportco.,Ltd
+86-18532138899 +86-18532138899 L18532138899@163.com China 939 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29791 60
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +8618949832763 info@tnjchem.com China 2986 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29884 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58

View Lastest Price from Octyl gallate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Octyl gallate  pictures 2024-11-21 Octyl gallate
1034-01-1
US $6.00 / kg 1kg 99% 2000KG/Month HebeiShuoshengImportandExportco.,Ltd
Octyl gallate pictures 2024-11-21 Octyl gallate
1034-01-1
US $0.00 / kg 1kg 99% 500mt/year Jinan Finer Chemical Co., Ltd
Octyl Gallate pictures 2024-11-20 Octyl Gallate
1034-01-1
US $65.00-20.00 / kg 1kg 99% 20ton Hebei Zhuanglai Chemical Trading Co.,Ltd
  • Octyl gallate  pictures
  • Octyl gallate
    1034-01-1
  • US $6.00 / kg
  • 99%
  • HebeiShuoshengImportandExportco.,Ltd
  • Octyl gallate pictures
  • Octyl gallate
    1034-01-1
  • US $0.00 / kg
  • 99%
  • Jinan Finer Chemical Co., Ltd
  • Octyl Gallate pictures
  • Octyl Gallate
    1034-01-1
  • US $65.00-20.00 / kg
  • 99%
  • Hebei Zhuanglai Chemical Trading Co.,Ltd
N-OCTYL GALLATE OCTYL 3,4,5-TRIHYDROXYBENZOATE OCTYL GALLATE GALLIC ACID OCTYL ESTER GALLIC ACID N-OCTYL ESTER Gallic Acid Octyl Eester Benzoic acid, 3,4,5-trihydroxy-, octyl ester OCTYL GALLATE(OCTYL 3,4,5-TRIHYDROXYBENZOATE) OCTYLGALLATE(RG) n-Octyl gallate, 98+% Progallin O 3,4,5-Trihydroxybenzoic acid octyl ester Gallic acid octyl Stabilizer GA-8 3,4,5-trihydroxy-benzoicacioctylester OCTYL 3,4,5-TRIHYDROXYBENZOATE FOR SYNTH Octyl gallate antioxidant, >=99.0% (HPLC) n-octylesterof3,4,5-trihydroxybenzoicacid oktylesterkyselinygallove Octyl-3,4,5-trihydroxybenzoat n-OctylGallate> Octyl gallate CRS Octyl gallate Solution in Methanol, 1000μg/mL C13998295 GalliCacid-octyLester 1034-01-1 1034-1-1 1034-01-0 345HO3C6H2CO2CH27CH3 Analytical Chromatography Product Catalog Alphabetic Analytical Standards Aromatic Esters