Mangiferin
- CAS No.
- 4773-96-0
- Chemical Name:
- Mangiferin
- Synonyms
- chinonin;Mangiferin Standard;2-beta-d-glucopyranosyl-1,3,6,7-tetrahydroxy-9h-xanthen-9-on;aphloiol;chinomin;ChinoMine;MANGIFERN;alpizarin;hedysarid;Mangiferin
- CBNumber:
- CB8723435
- Molecular Formula:
- C19H18O11
- Molecular Weight:
- 422.34
- MDL Number:
- MFCD00075656
- MOL File:
- 4773-96-0.mol
Melting point | 269-270°C |
---|---|
storage temp. | 2-8°C |
solubility | DMSO (Slightly, Sonicated), Methanol (Slightly), Pyridine (Slightly, Heated) |
Boiling point | 842.7±65.0 °C(Predicted) |
Density | 1.843±0.06 g/cm3(Predicted) |
pka | 6.09±0.20(Predicted) |
form | Solid |
color | Pale Yellow |
Stability | Hygroscopic |
InChIKey | AEDDIBAIWPIIBD-AZBPZEDSNA-N |
SMILES | OC1=C([C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)C(O)=CC2OC3=CC(O)=C(O)C=C3C(=O)C1=2 |&1:3,4,5,7,9,r| |
LogP | 0.130 (est) |
CAS DataBase Reference | 4773-96-0(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | 1M84LD0UMD |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS06 |
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Signal word | Danger | |||||||||
Hazard statements | H300 | |||||||||
Precautionary statements | P264-P270-P301+P310-P405-P501 | |||||||||
Hazard Codes | T+,Xi,Xn | |||||||||
Risk Statements | 28-36/37/38-22 | |||||||||
Safety Statements | 22-28-36/37-45-36-26-24/25 | |||||||||
RIDADR | UN 3462 6.1/PG 1 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | OP1927800 | |||||||||
HS Code | 29389090 | |||||||||
NFPA 704 |
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Mangiferin price More Price(48)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | M3547 | Mangiferin from Mangifera indica bark | 4773-96-0 | 1g | $409 | 2024-03-01 | Buy |
Sigma-Aldrich | 06279 | Mangiferin analytical standard | 4773-96-0 | 10mg | $152 | 2024-03-01 | Buy |
Cayman Chemical | 22360 | Mangiferin ≥98% | 4773-96-0 | 100mg | $41 | 2024-03-01 | Buy |
Cayman Chemical | 22360 | Mangiferin ≥98% | 4773-96-0 | 1g | $302 | 2024-03-01 | Buy |
Sigma-Aldrich | Y0001751 | Mangiferin European Pharmacopoeia (EP) Reference Standard | 4773-96-0 | y0001751 | $61.2 | 2024-03-01 | Buy |
Mangiferin Chemical Properties,Uses,Production
Description
Mangiferin is a plant natural polyphenol of C-glycosylxanthone structure and various pharmacological activities. It can be found in many plant species, among which the mango tree (Mangifera indica) is one of the primary sources. Mangiferin is also present in some medicinal herbs, influencing their therapeutic and preventive properties, and in honeybush (Cyclopia sp.), a popular South African herbal tea. Mangiferin dissolves well in water, so it can be easily extracted into infusions and decoctions. In the mangiferin molecule, four aromatic hydroxyl groups determine its strong antiradical and antioxidant properties. Mangiferin is also an efficient iron chelator, therefore preventing the generation of hydroxyl radicals in Fenton-type reactions[1].
Chemical Properties
Yellow powder
Uses
MAO inhibitor, immunostimulant
Uses
Mangiferin is a xanthonoid, a chemical compound found in mangoes and in Anemarrhena asphodeloides rhizomes. Mangiferin has effect of hepatinica and choleretic, and is used to therapy hepatitis. Mangiferin is an anti-inflammatory, antivirotic, central nervous system inhibit function and immunologic suppression. Mangiferin has curative effect on chronic bronchitis. Mangiferin has cytotoxicity effect on hepatocellularcarcinoma ce1l, and may induce apoptosis. Mangiferin has the effect of antioxidation and delaying caducity.
Definition
ChEBI: A C-glycosyl compound consisting of 1,3,6,7-tetrahydroxyxanthen-9-one having a beta-D-glucosyl residue at the 6-position.
General Description
Mangiferin (MGF) is a natural bioactive polyphenol predominantly isolated from the Mangifera indica (Mango) tree. It has a xanthone glucoside structure. Mangiferin can also be found in other angiosperm plants and herbs.
Biochem/physiol Actions
Mangiferin has various pharmacological properties including antioxidant, anti-diabetic, anti-bacterial, cardioprotective, neuroprotective, and immunomodulatory activities. It has also displayed antidiabetic, antihyperlipidemic, and antiatherogenic properties in streptozotocin-induced diabetic rats. MGF exerts chemotherapeutic and chemo-preventative activities. It displays antioxidant, analgesic, and hepatoprotective activity against carbon tetrachloride-induced liver injury. MGF is a known accelerator of gastrointestinal transit (GIT).
References
[1] Adam Matkowski. “Mangiferin - a bioactive xanthonoid, not only from mango and not just antioxidant.” Mini reviews in medicinal chemistry 13 3 (2013): 439–55.
Mangiferin Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +86-19164747840 +86-13119157289 | 13119157289@163.com | China | 2972 | 58 |
Bonerge(Hunan) Lifescience Co., Ltd. | +86-731-82791134 +86-18801900056 | hank.h@bonerge.com | China | 30 | 58 |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +8615383190639 | admin@86-ss.com | China | 1000 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21668 | 55 |
Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 | sales@fine-chemtech.com | CHINA | 885 | 55 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29892 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3777 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
View Lastest Price from Mangiferin manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-08-28 | Mangiferin
4773-96-0
|
US $22895.00-22880.00 / Grams | 1Grams | 99.99% | 100Tons | Hebei Dangtong Import and export Co LTD | ||
2024-08-28 | Mangiferin
4773-96-0
|
US $999.00-666.00 / ton | 1ton | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | ||
2024-08-28 | Mangiferin
4773-96-0
|
US $0.00-0.00 / kg | 1kg | 50%-98% | 1000kg | Changsha Staherb Natural Ingredients Co., Ltd. |
- Mangiferin
4773-96-0
- US $22895.00-22880.00 / Grams
- 99.99%
- Hebei Dangtong Import and export Co LTD
- Mangiferin
4773-96-0
- US $999.00-666.00 / ton
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
- Mangiferin
4773-96-0
- US $0.00-0.00 / kg
- 50%-98%
- Changsha Staherb Natural Ingredients Co., Ltd.