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CARNOSOL

CAS No.
5957-80-2
Chemical Name:
CARNOSOL
Synonyms
carnol;CARNOSOL;D-α-Alanine;Carnosol-RM;CARNOSOL(RG);CARNOSOL USP/EP/BP;Carnosol(P)(Request Quote);Carnosol, froM RoseMarinus officinalis;Carnosol, 98%, from Rosemarinus officinalis;(5b,7a)-11,12-Dihydroxy-7,20-epoxyabieta-8,11,13-trien-20-one
CBNumber:
CB8736565
Molecular Formula:
C20H26O4
Molecular Weight:
330.42
MDL Number:
MFCD02752467
MOL File:
5957-80-2.mol
MSDS File:
SDS
Last updated:2024-11-19 23:02:33

CARNOSOL Properties

Melting point 240~242℃
Boiling point 524.8±50.0 °C(Predicted)
Density 1.26±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility DMSO:66.0(Max Conc. mg/mL);199.74(Max Conc. mM)
pka 8.91±0.40(Predicted)
form Solid
color White
LogP 2.832 (est)
FDA UNII 483O455CKD

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H317
Precautionary statements  P280-P302+P352
Safety Statements  24/25
WGK Germany  3
HS Code  29322090
Hazardous Substances Data 5957-80-2(Hazardous Substances Data)

CARNOSOL price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C9617 Carnosol 5957-80-2 5mg $380 2024-03-01 Buy
Sigma-Aldrich 49702 Carnosol analytical standard 5957-80-2 10mg $747 2024-03-01 Buy
Cayman Chemical 89800 Carnosol ≥96% 5957-80-2 1mg $45 2024-03-01 Buy
Cayman Chemical 89800 Carnosol ≥96% 5957-80-2 5mg $198 2024-03-01 Buy
Cayman Chemical 89800 Carnosol ≥96% 5957-80-2 10mg $351 2024-03-01 Buy
Product number Packaging Price Buy
C9617 5mg $380 Buy
49702 10mg $747 Buy
89800 1mg $45 Buy
89800 5mg $198 Buy
89800 10mg $351 Buy

CARNOSOL Chemical Properties,Uses,Production

Description

Carnosol is a phytopolyphenol found in Rosemary that functions as an antioxidant, antimicrobial, & anticarcinogen.

Description

Carnosol is a phenol that has been found in rosemary (R. officinalis) and has diverse biological activities. It decreases nitric oxide (NO) production in mouse peritoneal exudate macrophages when used at concentrations ranging from 6 to 25 μM. Carnosol scavenges peroxyl and hydroxyl radicals and inhibits lipid peroxidation in cell-free assays. It inhibits 5-lipoxygenase (5-LO; IC50 = 0.1 μM for the recombinant human enzyme) and the synthesis of leukotrienes in human polymorphonuclear leukocytes (PMNs; IC50 = 7 μM). In vivo, carnosol (200 mg/kg) reduces mammary DNA adduct formation and tumorigenesis in a rat model of DMBA-induced mammary tumorigenesis.

Chemical Properties

White powder

Uses

Carnosol is a phytopolyphenol found in Rosemary that functions as an antioxidant, antimicrobial, & anticarcinogen.

Definition

ChEBI: Carnosol is a diterpenoid.

Cytotoxicity

IC50 (μg/mL): 65 (HL-60), 58 (K562), 50(Hep G2), 48 (MCF-7), 53 (MOLT-4)(Farimani et al. 2012)
IC50 (μg/mL): 61.46 (AGS) (Areche et al.2009)
IC50 (μg/mL): 2 (P388) (Aoyagi et al.2006)
IC50 (μg/mL): 1.19 (A2780), 3.30(SW1573), 8.59 (WiDr), 7.93 (T-47D),1.29 (HBL-100) (Guerrero et al. 2006).

CARNOSOL Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 205)Suppliers
Supplier Tel Email Country ProdList Advantage
BINBO BIOLOGICAL CO.,LTD
+8618629063126 info@binbobiological.com China 423 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29880 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3772 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Shanghai Standard Technology Co., Ltd.
18502101150 ft-sales@nature-standard.com CHINA 1923 58
Wuhan ChemNorm Biotech Co.,Ltd.
+86-27-8439 4403 18971486879 sales@chemnorm.com CHINA 2935 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58

View Lastest Price from CARNOSOL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
CARNOSOL pictures 2024-12-20 CARNOSOL
5957-80-2
US $0.00 / mg 20mg ≥98% HPLC 1000KG Changsha Staherb Natural Ingredients Co., Ltd.
Carnosol pictures 2024-11-28 Carnosol
5957-80-2
US $0.00 / kg 1kg 99.8% 1000 kg BINBO BIOLOGICAL CO.,LTD
Carnosol pictures 2024-11-19 Carnosol
5957-80-2
US $39.00-113.00 / mg 99% 10g TargetMol Chemicals Inc.
  • CARNOSOL pictures
  • CARNOSOL
    5957-80-2
  • US $0.00 / mg
  • ≥98% HPLC
  • Changsha Staherb Natural Ingredients Co., Ltd.
  • Carnosol pictures
  • Carnosol
    5957-80-2
  • US $0.00 / kg
  • 99.8%
  • BINBO BIOLOGICAL CO.,LTD
  • Carnosol pictures
  • Carnosol
    5957-80-2
  • US $39.00-113.00 / mg
  • 99%
  • TargetMol Chemicals Inc.

CARNOSOL Spectrum

1,3,4,9,10,10AS-HEXAHYDRO-5,6-DIHYDROXY-1,1-DIMETHYL-7-ISO-PROPYL-2H-9S,4AR-(EPOXYMETHANO)PHENANTHREN-12-ONE 1,3,4,9,10AS-HEXAHYDRO-5,6-DIHYDROXY-1,1-DIMETHYL-7-ISO-PROPYL-2H-9S,4AR-(EPOXYMETHANO)PHENANTHREN-12-ONE 1,2,3,4,4A,9,10,10AS-OCTAHYDRO-5,6-DIHYDROXY-1,1-DIMETHYL-7-ISOPROPYL-9S, 4AR (EPOXYMETHANO)PHENANTHREN-12-ONE CARNOSOL(RG) CARNOSOL Carnosol, froM RoseMarinus officinalis Carnosol, 98%, from Rosemarinus officinalis 2H-9,4a-(Epoxymethano)phenanthren-12-one, 1,3,4,9,10,10a-hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-, (4aR,9S,10aS)- CARNOSOL USP/EP/BP (4aR,9S,10aS)-5,6-Dihydroxy-7-isopropyl-1,1-dimethyl-2,3,4,9,10,10a-hexahydro-1H-9,4a-(epoxymethano)phenanthren-12-one D-α-Alanine carnol (5b,7a)-11,12-Dihydroxy-7,20-epoxyabieta-8,11,13-trien-20-one Carnosol(P)(Request Quote) Carnosol-RM 5957-80-2 chemical reagent pharmaceutical intermediate Miscellaneous Natural Products Antioxidant Biochemicals Found in Plants Nutrition Research phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract