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Danofloxacin mesylate

CAS No.
119478-55-6
Chemical Name:
Danofloxacin mesylate
Synonyms
Advoci;Nofloxacin;CP-76136-27;Dafloxacin mesylate;Danofloxacin Mesylat;DANOFLOXACIN MESYLATE;DANOFLOXACIN MESULATE;DANOFLOXACIN MESILATE;Mesylate Danofloxacin;DANOFLOXANCIN MESYLATE
CBNumber:
CB8736590
Molecular Formula:
C20H24FN3O6S
Molecular Weight:
453.48
MDL Number:
MFCD00673687
MOL File:
119478-55-6.mol
Last updated:2024-11-19 23:02:33

Danofloxacin mesylate Properties

Melting point 337-339°C
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility Aqueous Base (Slightly, Sonicated), DMSO (Slightly, Sonicated)
form Solid
color White to Off-White
Stability Hygroscopic
CAS DataBase Reference 119478-55-6(CAS DataBase Reference)
FDA UNII 94F3SX3LEM

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Warning
Hazard statements  H412-H373
Precautionary statements  P273-P501-P260-P314-P501
Safety Statements  24/25
HS Code  29339900

Danofloxacin mesylate price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 22408 Danofloxacin (mesylate) ≥98% 119478-55-6 50mg $44 2024-03-01 Buy
Cayman Chemical 22408 Danofloxacin (mesylate) ≥98% 119478-55-6 100mg $74 2024-03-01 Buy
Cayman Chemical 22408 Danofloxacin (mesylate) ≥98% 119478-55-6 250mg $172 2024-03-01 Buy
Cayman Chemical 22408 Danofloxacin (mesylate) ≥98% 119478-55-6 1g $469 2024-03-01 Buy
Usbiological 271209 Danofloxacin mesylate 119478-55-6 500mg $360 2021-12-16 Buy
Product number Packaging Price Buy
22408 50mg $44 Buy
22408 100mg $74 Buy
22408 250mg $172 Buy
22408 1g $469 Buy
271209 500mg $360 Buy

Danofloxacin mesylate Chemical Properties,Uses,Production

Description

Danofloxacin is a fluoroquinolone antibiotic and a type II topoisomerase inhibitor. It has a broad antimicrobial spectrum. It can be used as an anti-infective agent for veterinary use only.

Brand Name(s) in US

Advocin

Reference

J. A. Schrickx, J. Fink-Gremmels, Danofloxacin-mesylate is a substrate for ATP-dependent efflux transporters, British Journal of Pharmacology, 2009, vol. 150, pp. 463-469

Description

Danofloxacin is a fluoroquinolone antibiotic. In vitro, danofloxacin has activity against 68 field isolates of Mycoplasma species isolated from cattle, swine, and poultry with MICs ranging from 8 to 500 nM. It is protective in vivo against P. multocida, E. coli, and S. choleraesuis in mice with protective doses of 0.31, 0.40, and 2.42 mg/kg, respectively. Formulations containing danofloxacin are widely used to prevent infectious disease in livestock.

Chemical Properties

Crystalline Solid

Uses

Fluorinated quinolone antibacterial.

Uses

Danofloxacin is a fluoroquinolone antibacterial for veterinary use, with MIC90 of 0.28 μM

Definition

ChEBI: Danofloxacin mesylate is a member of quinolines.

Veterinary Drugs and Treatments

Danofloxacin mesylate injection is indicated for the treatment of Bovine Respiratory Disease (BRD) associated with Mannheimia (Pasturella) hemolytica and P. multocida in cattle (not dairy or veal). Because of the drug’s spectrum of activity, it may also be of benefit in the treatment of infections caused by Histophilus somni (Haemophilus somnus) or M. bovis, but the drug is not labeled (at the time of writing) for treating these pathogens. In other countries, danofloxacin may be labeled for use in swine and chickens (non-laying), but in the USA it is illegal to use the drug in an extralabel manner in food-producing species.
Danofloxacin may be of benefit in treating susceptible infections in adult horses, camelids and other non-food producing species.

Danofloxacin mesylate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 243)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Weibang Biotechnology Co., Ltd
+8615531157085 abby@weibangbio.com China 8812 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-81148696 +86-15536356810 1022@dideu.com China 3882 58
Hebei Mojin Biotechnology Co., Ltd
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shandong perfect biotechnology co.ltd
+86-53169958659 +86-13153181156 sales@sdperfect.com China 294 58
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+8618092446649 sarah@tnjone.com China 1143 58
Henan Suikang Pharmaceutical Co.,Ltd.
+86-18239973690 +86-18239973690 sales@suikangpharm.com China 311 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29811 58

View Lastest Price from Danofloxacin mesylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Danofloxacin mesylate pictures 2024-11-22 Danofloxacin mesylate
119478-55-6
US $0.00 / Kg/Drum 1KG 99% 1000kg WUHAN FORTUNA CHEMICAL CO., LTD
Danofloxacin mesylate pictures 2024-11-22 Danofloxacin mesylate
119478-55-6
US $0.00 / kg 25kg 99.0% 10tongs Henan Suikang Pharmaceutical Co.,Ltd.
Danofloxacin mesylate pictures 2024-11-19 Danofloxacin mesylate
119478-55-6
US $64.00-155.00 / mg 99.66% 10g TargetMol Chemicals Inc.
1-Cyclopropyl-6-fluoro-1,4-dihydro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-quinolin-3-carboxylic acid methanesulfonate (1:1) 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-, methanesulfonate (1:1) Mesylate Dan Nuosha star DANOFLOXACIN MESILATE DANOFLOXACIN MESULATE DANOFLOXACIN MESYLATE DANOFLOXANCIN MESYLATE 1-cyclopropyl-6-fluoro-7-[(1s,4s)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid monomethanesulfonate Nofloxacin Advoci CP-76136-27 Danofloxacin Methanesulfonate 1-Cyclopropyl-6-fluoro-1,4-dihydro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-3-Quinolinecarboxylic Acid Mesylate Dafloxacin mesylate Danofloxacin Mesylat Danofloxacin Mesylate Dafloxacin Mesylate 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-7-(5-Methyl-2,5-diazabicyclo[2.2.1]hept-2-yl)-4-oxo-, (1S)-, MonoMethanesulfonate Mesylate Danofloxacin Danofloxacin mesylate USP/EP/BP Danofloxacin Mesylate (CP 76136-27) TIANFU-CHEM - Danofloxacin mesylate Danofloxacin mesylate (DM), 98% 1-Cyclopropyl-6-fluoro-7-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid methanesulfonic acid salt 1-cyclopropyl-6-fluoro-7-(5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)-4-oxo-3-quinolinecarboxylic acid C11960500 Danofloxacin mesylate 119478-55-6 C19H20FN3O3CH4O3S C20H24FN3O6S C19H20FN3O3CH3SO3H CH4O3SC19H20FN3O3 Intermediates & Fine Chemicals Pharmaceuticals