NEOMYCIN B
- CAS No.
- 119-04-0
- Chemical Name:
- NEOMYCIN B
- Synonyms
- actilin;actiline;framygen;Framidal;Framycin;enterfram;Francetin;Fraquinol;framycetin;NEOMYCIN B
- CBNumber:
- CB8761428
- Molecular Formula:
- C23H46N6O13
- Molecular Weight:
- 614.64
- MDL Number:
- MFCD09788228
- MOL File:
- 119-04-0.mol
Melting point | >194°C (dec.) |
---|---|
Boiling point | 658.4°C (rough estimate) |
Density | 1.3548 (rough estimate) |
refractive index | 1.6000 (estimate) |
storage temp. | 2-8°C |
solubility | Aqueous Acid (Slightly), Water (Slightly) |
form | liquid |
pka | 12.93±0.70(Predicted) |
color | clear |
Merck | 13,6482 |
Stability | Hygroscopic |
EWG's Food Scores | 1 |
FDA UNII | 4BOC774388 |
ATC code | D09AA01,R01AX08,S01AA07 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS08 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H317-H334 | |||||||||
Precautionary statements | P261-P280-P284-P304+P340-P333+P313-P342+P311 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 42/43-63-36/37/38 | |||||||||
Safety Statements | 26-36/37/39-45-36/37-23 | |||||||||
WGK Germany | 2 | |||||||||
F | 8 | |||||||||
NFPA 704 |
|
NEOMYCIN B price More Price(8)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | N1142 | Neomycin solution with 10 mg/mL neomycin in 0.9% NaCl, sterile-filtered, BioReagent, suitable for cell culture | 119-04-0 | 20ml | $17.3 | 2024-03-01 | Buy |
TRC | N389983 | NeomycinB | 119-04-0 | 10mg | $1695 | 2021-12-16 | Buy |
Usbiological | 285570 | Neomycin solution | 119-04-0 | 20g | $410 | 2021-12-16 | Buy |
Usbiological | 165605 | Neomycin B | 119-04-0 | 1mg | $496 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 60608 | NeomycinB | 119-04-0 | 1mg | $675 | 2021-12-16 | Buy |
NEOMYCIN B Chemical Properties,Uses,Production
Uses
Neomycin C is an aminoglycoside antibiotic found in many topical medications. Neomycin has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia.
Definition
ChEBI: A tetracyclic antibacterial agent derived from neomycin, being a glycoside ester of neamine and neobiosamine B.
General Description
Chemical structure: aminoglycoside
Biochem/physiol Actions
Neomycin is an aminoglycoside antibiotic, produced by Streptomyces containing a minimum of 85% neomycin B. It acts as a selection agent for prokaryotic cells transformed using the neo selectable marker gene. Neomycin trisulfate is used to study the cytototoxic side effects of antibiotics, platelet-derived growth factor responses in certain fibroblasts and extraction of nuclear phosphatidylinositol 4,5-bisphosphate-interacting proteins. This product is recommended for use in cell culture applications at 5 mL/L.Mode of action: This product acts by binding to the 30S and 50S subunits, causing miscoding and inhibiting initiation and elongation during protein synthesis. Neomycin also blocks voltage-sensitive Ca2+ channels without affecting the Na+/Ca2+ antiporter in neurons.Antimicrobial spectrum: Neomycin acts against both gram-positive and gram-negative bacteria
NEOMYCIN B Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30240 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 7724 | 58 |
BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19741 | 58 |
Alfa Chemistry | Info@alfa-chemistry.com | United States | 24072 | 58 | |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12335 | 58 |
Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9891 | 58 |
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