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FABP-IN-1

FABP-IN-1 Structure
FABP-IN-1 structure
CAS No.
2132990-90-8
Chemical Name:
FABP-IN-1
Synonyms
FABP-IN-1;FABP IN 1,FABPIN1;1,3-Cyclobutanedicarboxylic acid, 2,4-bis(2-methoxyphenyl)-, 1-(1-naphthalenyl) ester, (1β,2R,3α,4R)-rel-
CBNumber:
CB88054397
Molecular Formula:
C30H26O6
Molecular Weight:
482.52
MDL Number:
MFCD34179482
MOL File:
2132990-90-8.mol
Last updated:2023-05-21 10:59:17
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FABP-IN-1 Properties

Boiling point 671.3±55.0 °C(Predicted)
Density 1.280±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 200 mg/mL (414.49 mM; Need ultrasonic)
pka 4.10±0.70(Predicted)

FABP-IN-1 Chemical Properties,Uses,Production

Biological Activity

FABP-IN-1 (Compounds 4b) is a high affinity fatty acid binding protein (FABP) inhibitor. FABP-IN-1 inhibits FABP3, FABP5, and FABP7 with Ki values of 0.69 μM, 0.55 μM and 0.67 μM, respectively. FABP-IN-1 displays potent antinociceptive effects[1]. FABP-IN-1 (Compounds 4b; 20 mg/kg; intraperitoneal injection; for 90 minutes; male wild-type C57BL/6 mice) treatment displays potent antinociceptive effects in CFA model[1].

References

[1]. Yan S, et al. SAR studies on truxillic acid mono esters as a new class of antinociceptive agents targeting fatty acid binding proteins. Eur J Med Chem. 2018 Jun 25;154:233-252.

FABP-IN-1 Preparation Products And Raw materials

Raw materials

Preparation Products

FABP-IN-1 Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Shanghai Yiyan Biotechnology Co. , Ltd. 021-69985186 13611928337 3427709316@qq.com China 7984 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9282 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
TargetMol Chemicals Inc. 58
Shanghai Yiyan Biotechnology Co. , Ltd. 58
RD International Technology Co., Limited 58
FABP-IN-1 FABP IN 1,FABPIN1 1,3-Cyclobutanedicarboxylic acid, 2,4-bis(2-methoxyphenyl)-, 1-(1-naphthalenyl) ester, (1β,2R,3α,4R)-rel- 2132990-90-8