PLECONARIL
- CAS No.
- 153168-05-9
- Chemical Name:
- PLECONARIL
- Synonyms
- Picovir;VP 63843;Rimiducid;WIN 63843;PLECONARIL;Pleconarilis;Pleconaril-d4;PLECONARIL USP/EP/BP;Pleconaril VP-63843 Win-63843;3-[3,5-DiMethyl-4-[3-(3-Methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoroMethyl)-
- CBNumber:
- CB8840318
- Molecular Formula:
- C18H18F3N3O3
- Molecular Weight:
- 381.35
- MDL Number:
- MFCD00923611
- MOL File:
- 153168-05-9.mol
- MSDS File:
- SDS
Melting point | 61-62° |
---|---|
Boiling point | 481.2±55.0 °C(Predicted) |
Density | 1.271 |
storage temp. | room temp |
solubility | DMSO: ≥10mg/mL (warmed) |
form | powder |
pka | -1.33±0.10(Predicted) |
color | white to beige |
FDA UNII | 9H4570Q89D |
NCI Drug Dictionary | rimiducid |
ATC code | J05AX06 |
PLECONARIL price More Price(25)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SML0307 | Pleconaril ≥98% (HPLC) | 153168-05-9 | 10mg | $215 | 2024-03-01 | Buy |
Sigma-Aldrich | SML0307 | Pleconaril ≥98% (HPLC) | 153168-05-9 | 50mg | $316 | 2024-03-01 | Buy |
Cayman Chemical | 28461 | Pleconaril | 153168-05-9 | 10mg | $121 | 2024-03-01 | Buy |
Cayman Chemical | 28461 | Pleconaril | 153168-05-9 | 100mg | $662 | 2024-03-01 | Buy |
Cayman Chemical | 28461 | Pleconaril | 153168-05-9 | 25mg | $241 | 2024-03-01 | Buy |
PLECONARIL Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
Pleconaril has been used as a control or reference compound to assess the antiviral activities of the benzothiophene and other heteroaromatic derivatives against hRV-B14, hRV-A21 and hRV-A71.
Uses
Picornavirus replication inhibitor. Antiviral.
General Description
Pleconaril is a drug, that has antiviral activity.
Pharmaceutical Applications
An oxadiazole active against most enteroviruses and rhinoviruses. It binds to the hydrophobic pocket of the virus capsid protein VP1, inducing conformational changes that lead to altered receptor binding and viral uncoating. Concerns over safety and efficacy have constrained development of the drug.
Biochem/physiol Actions
Pleconaril is an effective drug against enteroviral infections. It can be used to treat chronic meningoencephalitis caused by echo virus 6.This can block viral replication by blocking the viral uncoating process and viral attachment to host cell receptors.
PLECONARIL Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29826 | 58 |
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21149 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 25349 | 58 |
Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9624 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10522 | 58 |
View Lastest Price from PLECONARIL manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-07-16 | PLECONARIL USP/EP/BP
153168-05-9
|
US $1.10 / g | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited | ||
2019-12-20 | PLECONARIL
153168-05-9
|
US $0.00 / KG | 1KG | 99% | kg/T | Career Henan Chemical Co |
- PLECONARIL USP/EP/BP
153168-05-9
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
- PLECONARIL
153168-05-9
- US $0.00 / KG
- 99%
- Career Henan Chemical Co