Bucumolol
- CAS No.
- 58409-59-9
- Chemical Name:
- Bucumolol
- Synonyms
- Bucumolol;dl-Bucumolol;8-[3-(tert-Butylamino)-2-hydroxypropoxy]-5-methylcoumarin;8-[2-Hydroxy-3-(tert-butylamino)propoxy]-5-methylcoumarin;8-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-5-methyl-2H-1-benzopyran-2-one
- CBNumber:
- CB8875453
- Molecular Formula:
- C17H23NO4
- Molecular Weight:
- 305.37
- MDL Number:
- MFCD00864572
- MOL File:
- 58409-59-9.mol
Last updated:2023-05-04 17:34:40
| Melting point | >163° (dec.) |
|---|---|
| Boiling point | 490.7±45.0 °C(Predicted) |
| Density | 1.160±0.06 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 13.81±0.20(Predicted) |
| color | White to Off-White |
| FDA UNII | U8WVJ3501L |
Bucumolol Chemical Properties,Uses,Production
Originator
Bucumarol,Sankyo,Japan,1982
Uses
Bucumolol is?an antihypertensive agent and a β-adrenoceptor blocker.
Definition
ChEBI: Bucumolol is a member of coumarins.
Manufacturing Process
A mixture of 3 g of 8-(2-hydroxy-3-chloropropoxy)-5-methyl coumarin, 4.3 g
of t-butylamine and 60 ml of ethanol is heated at 100°C in a sealed tube for
15 hours. The reaction mixture is concentrated under reduced pressure to
dryness. The residue is recrystallized from a mixture of ethanol and ether to
give 2.1 g of the desired product melting at 226° to 228°C (with
decomposition).
In practice it is usually used as hydrochloride.
Therapeutic Function
Beta-adrenergic blocker
Bucumolol Preparation Products And Raw materials
Global( 8)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Supplier | Advantage |
|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 58 |
58409-59-9(Bucumolol)Related Search:
Bucumolol
dl-Bucumolol
8-[2-Hydroxy-3-(tert-butylamino)propoxy]-5-methylcoumarin
8-[3-(tert-Butylamino)-2-hydroxypropoxy]-5-methylcoumarin
8-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-5-methyl-2H-1-benzopyran-2-one
58409-59-9