| Company Name: |
United States Biological
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| Tel: |
800.520.3011 or 781.639.5092 |
| Email: |
chemicals@usbio.net |
| Products Intro: |
Product Name:Bucumolol
CAS:58409-59-9
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| Company Name: |
Leancare Ltd.
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| Tel: |
+33 962096793 |
| Email: |
enquiry@leancare.co.uk |
| Products Intro: |
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| | Bucumolol Basic information |
| Product Name: | Bucumolol | | Synonyms: | Bucumolol;dl-Bucumolol;8-[2-Hydroxy-3-(tert-butylamino)propoxy]-5-methylcoumarin;8-[3-(tert-Butylamino)-2-hydroxypropoxy]-5-methylcoumarin;8-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-5-methyl-2H-1-benzopyran-2-one | | CAS: | 58409-59-9 | | MF: | C17H23NO4 | | MW: | 305.37 | | EINECS: | | | Product Categories: | | | Mol File: | 58409-59-9.mol |  |
| | Bucumolol Chemical Properties |
| Melting point | >163° (dec.) | | Boiling point | 490.7±45.0 °C(Predicted) | | density | 1.160±0.06 g/cm3(Predicted) | | storage temp. | Refrigerator | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Solid | | pka | 13.81±0.20(Predicted) | | color | White to Off-White |
| | Bucumolol Usage And Synthesis |
| Originator | Bucumarol,Sankyo,Japan,1982 | | Uses | Bucumolol is?an antihypertensive agent and a β-adrenoceptor blocker. | | Definition | ChEBI: Bucumolol is a member of coumarins. | | Manufacturing Process | A mixture of 3 g of 8-(2-hydroxy-3-chloropropoxy)-5-methyl coumarin, 4.3 g
of t-butylamine and 60 ml of ethanol is heated at 100°C in a sealed tube for
15 hours. The reaction mixture is concentrated under reduced pressure to
dryness. The residue is recrystallized from a mixture of ethanol and ether to
give 2.1 g of the desired product melting at 226° to 228°C (with
decomposition).
In practice it is usually used as hydrochloride. | | Therapeutic Function | Beta-adrenergic blocker |
| | Bucumolol Preparation Products And Raw materials |
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