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dextilidine
- CAS No.
- 32447-90-8
- Chemical Name:
- dextilidine
- Synonyms
- dextilidine;2α-(Dimethylamino)-1-phenyl-3-cyclohexene-1β-carboxylic acid ethyl ester;2α-(Dimethylamino)-1α-phenyl-3-cyclohexene-1β-carboxylic acid ethyl ester;(1S,2S)-2-(Dimethylamino)-1-phenyl-3-cyclohexene-1-carboxylic acid ethyl ester;(1R,2R)-2-(Dimethylamino)-1-phenyl-3-cyclohexene-1-carboxylic acid ethyl ester;3-Cyclohexene-1-carboxylic acid, 2-(dimethylamino)-1-phenyl-, ethyl ester, (1S,2R)-
- CBNumber:
- CB8883083
- Molecular Formula:
- C17H23NO2
- Molecular Weight:
- 273.37
- MDL Number:
- MFCD00868712
- MOL File:
- 32447-90-8.mol
Last updated:2023-07-14 17:48:59
| Melting point | 56-58 °C |
|---|---|
| Boiling point | 354.2±42.0 °C(Predicted) |
| Density | 1.06±0.1 g/cm3(Predicted) |
| pka | 8.26±0.40(Predicted) |
| FDA UNII | 2728MV084C |
dextilidine Chemical Properties,Uses,Production
Definition
ChEBI: Dextilidine is an ethyl 2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate that has S configuration at the carbon bearing the phenyl group and R configuration at the carbon bearing the dimethylamino group. The opioid analgesic tilidine is the racemate comprising equimolar amounts of dextilidine and its enantiomer, ent-dextilidine. A prodrug, tilidine is converted by the liver to the active analgesic, nortilidine; virtually all of the opioid activity resides in the (1S,2R) isomer (i.e. the isomer derived from dextilidine). It has a role as an opioid analgesic and a prodrug. It is an enantiomer of an ent-dextilidine.
dextilidine Preparation Products And Raw materials
Raw materials
Preparation Products
dextilidine
2α-(Dimethylamino)-1-phenyl-3-cyclohexene-1β-carboxylic acid ethyl ester
2α-(Dimethylamino)-1α-phenyl-3-cyclohexene-1β-carboxylic acid ethyl ester
(1R,2R)-2-(Dimethylamino)-1-phenyl-3-cyclohexene-1-carboxylic acid ethyl ester
(1S,2S)-2-(Dimethylamino)-1-phenyl-3-cyclohexene-1-carboxylic acid ethyl ester
3-Cyclohexene-1-carboxylic acid, 2-(dimethylamino)-1-phenyl-, ethyl ester, (1S,2R)-
32447-90-8