Dexamethasone sodium phosphate EP Impurity B
- CAS No.
- 360-63-4
- Chemical Name:
- Dexamethasone sodium phosphate EP Impurity B
- Synonyms
- Unii-yjo1F9W10r;Einecs 206-636-7;Betamethasone phosphate;Betamethasone 21-phosphate;Betamethasone 21-phopsphate;Dexamethasone Impurity B(EP);Betamethasone dihydrogen phosphate;Betamethasone 21-(dihydrogen phosphate);Betamethasone Sodium Phosphate Impurity 3;Betamethasone-4,6,11,12,12-d5 21-Phosphate
- CBNumber:
- CB8939872
- Molecular Formula:
- C22H30FO8P
- Molecular Weight:
- 472.44
- MDL Number:
- MFCD01698987
- MOL File:
- 360-63-4.mol
FDA UNII | YJO1F9W10R |
---|
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() GHS08,GHS09 |
---|---|
Signal word | Danger |
Hazard statements | H410-H372-H360 |
Precautionary statements | P260-P264-P270-P314-P501-P273-P391-P501 |
Dexamethasone sodium phosphate EP Impurity B Chemical Properties,Uses,Production
Originator
Bentelan,Biofutura
Uses
Glucocorticoid.
Definition
ChEBI: Betamethasone phosphate is a steroid phosphate that is the 21-O-phospho derivative of betamethasone. It has a role as an anti-inflammatory agent and an immunosuppressive agent. It is a steroid phosphate, an 11beta-hydroxy steroid, a fluorinated steroid, a 17alpha-hydroxy steroid, a 20-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid and a tertiary alpha-hydroxy ketone. It is functionally related to a betamethasone. It is a conjugate acid of a betamethasone phosphate(2-).
Manufacturing Process
A solution of bistriethylamine phosphate was prepared by slowly adding 2.36
ml of 85% phosphoric acid to 20 ml of acetonitrile containing 9.9 ml, of
triethylamine at 20°C. This solution was added to a stirred mixture of 4.70 g
of 9α-fluoro-11β,17α,21-trihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione
21-methanesulfonate and 20 ml of acetonitrile. The mixture was heated under
reflux for 4 h and then evaporated under reduced pressure to a volume of 12
ml. This mixture was a concentrated solution of 9α-fluoro-11β,17α,21-
trihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione 21-phosphate
triethylamine salt with some inorganic phosphate.
The salt of 9α-fluoro-11β,17α,21-trihydroxy-16α-methyl-1,4-pregnadiene-
3,20-dione 21-phosphate may be converted to 9α-fluoro-11β,17α,21-
trihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione 21-phosphate by
treatment with acid (for example HCl).
brand name
Celestone (Schering).
Therapeutic Function
Glucocorticoid
Dexamethasone sodium phosphate EP Impurity B Preparation Products And Raw materials
Raw materials
Preparation Products
Dexamethasone sodium phosphate EP Impurity B Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +8615195660023 | sales@senfeida.com | China | 23053 | 58 |
ShenZhen H&D Pharmaceutical Technology Co., LTD | +86-0755-22677845 +86-13627253706 | sale@hdimpurity.com | China | 3389 | 58 |
Hebei Weibang Biotechnology Co., Ltd | +8615350571055 | Sibel@weibangbio.com | China | 5341 | 58 |
Nanjing MeiBo Biological Technology Co., Ltd. | 025-58619198 | sales@mbbio.com | China | 319 | 60 |
Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12338 | 58 |
Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9900 | 58 | |
Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7887 | 56 |
BOC Sciences | 16314854226 | info@bocsci.com | United States | 9926 | 65 |
PI & PI BIOTECH INC. | 020-81716320 17788709170 | Sales@pipitech.com | China | 2649 | 58 |
TOSUN PHARM | 020-61855200 13326451905 | 260366801@qq.com | China | 7713 | 58 |
View Lastest Price from Dexamethasone sodium phosphate EP Impurity B manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-08-22 | Betamethasone Sodium Phosphate Impurity 3
360-63-4
|
US $0.00-0.00 / mg | 10mg | 0.98 | 10g | ShenZhen H&D Pharmaceutical Technology Co., LTD |
-
- Betamethasone Sodium Phosphate Impurity 3
360-63-4
- US $0.00-0.00 / mg
- 0.98
- ShenZhen H&D Pharmaceutical Technology Co., LTD
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