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VU6007477
- CAS No.
- 2220141-46-6
- Chemical Name:
- VU6007477
- Synonyms
- VU6007477;1H-Pyrrolo[2,3-b]pyridine-6-carboxamide, 1-methyl-4-[[6-(1-methyl-1H-pyrazol-4-yl)-3-pyridinyl]methyl]-N-(tetrahydro-2H-pyran-4-yl)-
- CBNumber:
- CB89636763
- Molecular Formula:
- C24H26N6O2
- Molecular Weight:
- 430.5
- MDL Number:
- MOL File:
- 2220141-46-6.mol
Last updated:2023-03-31 09:12:58
VU6007477 Chemical Properties,Uses,Production
Description
VU6007477 is a novel M1 PAM. VU6007477 resulted in good rat M1 PAM potency (EC50 = 230 nM, 93% ACh max), minimal M1 agonist activity (agonist EC50 > 10 μM), good CNS penetration (rat braiplasma Kp = 0.28, Kp,uu = 0.32; mouse Kp = 0.16, Kp,uu = 0.18), and no cholinergic adverse events (AEs, e.g., seizures).
VU6007477 Preparation Products And Raw materials
Raw materials
Preparation Products
VU6007477 Suppliers
Global( 2)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd | 15317229551 | 15151849396@163.com | China | 994 | 58 |
TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 28091 | 58 |
Supplier | Advantage |
---|---|
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd | 58 |
TargetMol Chemicals Inc. | 58 |
VU6007477
1H-Pyrrolo[2,3-b]pyridine-6-carboxamide, 1-methyl-4-[[6-(1-methyl-1H-pyrazol-4-yl)-3-pyridinyl]methyl]-N-(tetrahydro-2H-pyran-4-yl)-
2220141-46-6