PYRROLIDINYL DIAMINOPYRIMIDINE OXIDE
- CAS No.
- 55921-65-8
- Chemical Name:
- PYRROLIDINYL DIAMINOPYRIMIDINE OXIDE
- Synonyms
- 2,6-diamino-4-(pyrrolidin-1-yl)pyrimidine 1-oxide;Kopyrrol;PYRROLIDINYL;Pyrrolidinyl Diaminopyrimide oxide;Pyrrolidyl diaminopyrimidine oxide;PYRROLIDINYL DIAMINOPYRIMIDINE OXIDE;6-pyrrolidine-2,4-diaminopyrimidin-3-oxide;2,4-Diamino-6-pyrrolidinopyrimidine 3-oxide;4-Pyrrolidine 2,6-diaminopyrimidine 1-oxide;3-oxy-6-pyrrolidin-1-yl-pyrimidine-2,4-diamine
- CBNumber:
- CB8964098
- Molecular Formula:
- C8H13N5O
- Molecular Weight:
- 195.22
- MDL Number:
- MFCD22041981
- MOL File:
- 55921-65-8.mol
- MSDS File:
- SDS
| Melting point | 278℃ (DEC.) |
|---|---|
| Boiling point | 549.3±60.0 °C(Predicted) |
| Density | 1.60 |
| storage temp. | 2-8°C(protect from light) |
| pka | 4.89±0.10(Predicted) |
| InChI | InChI=1S/C8H13N5O/c9-6-5-7(11-8(10)13(6)14)12-3-1-2-4-12/h5H,1-4,9H2,(H2,10,11) |
| InChIKey | FMVJDYVWXJHAFZ-UHFFFAOYSA-N |
| SMILES | C1(N)=NC(N2CCCC2)=CC(N)=[N+]1[O-] |
| EWG's Food Scores | 1 |
| FDA UNII | 23GGI87A7F |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H314 |
| Precautionary statements | P280-P305+P351+P338-P310 |
PYRROLIDINYL DIAMINOPYRIMIDINE OXIDE price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 153401 | 2,6-Diamino-4-(pyrrolidin-1-yl)pyrimidine 1-oxide 95% | 55921-65-8 | 5g | $583 | 2021-12-16 | Buy |
| Matrix Scientific | 153401 | 2,6-Diamino-4-(pyrrolidin-1-yl)pyrimidine 1-oxide 95% | 55921-65-8 | 10g | $972 | 2021-12-16 | Buy |
| Chemenu | CM167546 | 2,6-Diamino-4-(pyrrolidin-1-yl)pyrimidine1-oxide 97% | 55921-65-8 | 5g | $316 | 2021-12-16 | Buy |
| Crysdot | CD11104344 | 2,6-Diamino-4-(pyrrolidin-1-yl)pyrimidine1-oxide 97% | 55921-65-8 | 5g | $338 | 2021-12-16 | Buy |
PYRROLIDINYL DIAMINOPYRIMIDINE OXIDE Chemical Properties,Uses,Production
Uses
Pyrrolidinyl Diaminopyrimidine Oxide is a hair growth stimulant that can be used to treat hair loss. It can also be used in cosmetics to invent a dermocosmetic composition having a whitening or dark circle removal or anti-glare effect by containing a pyrrolidinyl diaminopyrimidine oxide compound as an active ingredient.
Synthesis
Pyrrolidinyl Diaminopyrimidine Oxide is prepared by the reaction of pyrrolidine and 2,6-diamino-4-chloro-pyrimidine N-oxide. The steps are as follows:
Pyrrolidine (7.47 g, 0.105 mol) and 2,6-diamino-4-chloropyrimidine N-oxide (16 g, 0.1 mol) were added to 100 mL ethanol solution, 10% NaOH (0.11 mol) was added dropwise under stirring, and then the reaction was carried out at 80 °C for 120 min. The progress of the reaction was monitored by high performance liquid chromatography. After the reaction is completed, it is cooled to below 5°C, the solvent is removed by filtration, the obtained solid product is washed with water, and recrystallized with hot water to obtain 2,6-diamino-4-pyrrolidinopyrimidine N-oxide as a colorless crystalline solid. Yield 92% (17.96 g), white crystalline powder, mp 276-278°C. IR spectrum (neat), νmax, cm-1: 1195 (C-N), 1346 (C-C), 1463 (N-O), 1613 (C=N), 1651 (C=C), 2856 (C-H), 3265 (C-H), 3298 (O-H), 3428 (N-H). 1H NMR spectrum (500 MHz, DMSO), δ, ppm: 1.87 s (4H, CH2), 3.25 s (4H, N-CH2), 5.08 s (1H, Ar-H), 6.78 s (4H, NH2). 13C NMR spectrum (101 MHz, DMSO), δC, ppm: 26.81, 48.05, 74.81, 153.85, 154.47, 154.60.
PYRROLIDINYL DIAMINOPYRIMIDINE OXIDE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beri Pharma Co., Ltd. | +8613417710166 | sales@zhberi.com | China | 227 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531157085 | abby@chuanghaibio.com | China | 8808 | 58 |
| Wuhan Haorong Biotechnology Co.,ltd | +86-18565342920; +8618565342920 | sales@chembj.net | China | 305 | 58 |
| Hebei Jingbo New Material Technology Co., Ltd | +8619931165850 | hbjbtech@163.com | China | 1000 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20235 | 58 |
| Hebei Saisier Technology Co., LTD | +86-18400010335 +86-18034520335 | admin@hbsaisier.cn | China | 1015 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| Hebei Longbang Technology Co., LTD | +86-18633929156 +86-18633929156 | admin@hblongbang.com | China | 972 | 58 |
| Hebei Shengyang Water Conservancy Engineering Co., Ltd. | +8615373025980 | clara@hbshengyang.com | China | 847 | 58 |
| HebeiShuoshengImportandExportco.,Ltd | +86-18532138899 +86-18532138899 | L18532138899@163.com | China | 939 | 58 |
View Lastest Price from PYRROLIDINYL DIAMINOPYRIMIDINE OXIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-24 | PYRROLIDINYL DIAMINOPYRIMIDINE OXIDE
55921-65-8
|
US $0.00-0.00 / kg | 1kg | 99% | 2000 | Wuhan Haorong Biotechnology Co.,Ltd | |
 |
2025-04-24 | Kopyrrol
55921-65-8
|
US $0.00-0.00 / kg | 1kg | 99.99% | 20 tons | Chongqing Soarwin Technology Co., Ltd | |
 |
2025-04-24 | Pyrrolidinyl Diaminopyrimidine Oxide
55921-65-8
|
US $0.00-0.00 / kg | 1kg | 99.99% | 20 tons | Chongqing Soarwin Technology Co., Ltd |
-
- PYRROLIDINYL DIAMINOPYRIMIDINE OXIDE
55921-65-8
- US $0.00-0.00 / kg
- 99%
- Wuhan Haorong Biotechnology Co.,Ltd
-
- Kopyrrol
55921-65-8
- US $0.00-0.00 / kg
- 99.99%
- Chongqing Soarwin Technology Co., Ltd
-
- Pyrrolidinyl Diaminopyrimidine Oxide
55921-65-8
- US $0.00-0.00 / kg
- 99.99%
- Chongqing Soarwin Technology Co., Ltd