(+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4-
- CAS No.
- 42203-78-1
- Chemical Name:
- (+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4-
- Synonyms
- Doi cpd hydrochloride;(+/-)-DOI hydrochloride;Amphetamine Impurity 1 HCl;(+/-)-DOI hydrochloride >=98% (HPLC), solid;(+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4-;DL-2,5-Dimethoxy-4-iodoamphetamine hydrochloride;4-Iodo-2,5-dimethoxyphenylisopropylamine, hydrochloride;(±)-2,5-Dimethoxy-4-Iodoamphetamine hydrochloride solution;4-Iodo-2,5-dimethoxy-α-methylbenzeneethanaminehydrochloride;4-Iodo-2,5-dimethoxy-α-methylbenzeneethanaminehydrochloride
- CBNumber:
- CB8973094
- Molecular Formula:
- C11H16INO2.ClH
- Molecular Weight:
- 357.613
- MDL Number:
- MFCD00055199
- MOL File:
- 42203-78-1.mol
- MSDS File:
- SDS
| Flash point | 9℃ |
|---|---|
| storage temp. | Store at RT |
| solubility | H2O: soluble10mg/mL |
| form | solid |
| color | white to off-white |
| Water Solubility | Soluble to 50 mM in water |
| FDA UNII | Q2E57V2WS3 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,T,F | |||||||||
| Risk Statements | 36/37/38-39/23/24/25-23/24/25-11 | |||||||||
| Safety Statements | 22-26-36-45-36/37-16-7 | |||||||||
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
(+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4- Chemical Properties,Uses,Production
Uses
Hydrochloride (cas# 42203-78-1) is a useful research chemical.??DOI Hydrochloride is a 5-??HT2A??/2C agonist that stimulates hypothalamic neurons to increase the secretion of several hormones
General Description
A Certified Spiking Solution? suited for GC/MS or LC/MS phenethylamine testing applications in forensic analysis, clinical toxicology, or urine drug testing. DOI is a D-substituted amphetamine in the phenethylamine family of hallucinogenic drugs. This designer drug is an extremely potent psychedelic with a long duration of action.
Biological Activity
Brain penetrant, mixed 5-HT 2A /5-HT 2C receptor agonist (K i values are 0.7, 2.4 and 20 nM for 5-HT 2A , 5-HT 2C and 5-HT 2B receptors respectively). Reduces rapid eye movement (REM) and slow wave sleep and increases waking in the rat. Hallucinogenic agent. Acts via 5-HT 2A receptors to inhibit the inflammatory effects of tumor necrosis factor (TNF)- α .
Biochem/physiol Actions
(±)-DOI hydrochloride is a potent and selective 5-HT2 serotonin receptor agonist that crosses the blood-brain barrier, increases dopamine turnover and the treatment with DOI counteracted the expression of the nicotine-induced locomotor and neurochemical sensitization, but had no effect on nicotine-induced behavioral disinhibition. The responses to DOI provide evidence that of these receptors are abundant in the cortex, and show relatively lower levels in hippocampus and cerebellum.
storage
Store at RT
(+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4- Preparation Products And Raw materials
Raw materials
Preparation Products
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