(±)-DOI 塩酸塩
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- CAS番号.
- 42203-78-1
- 化学名:
- (±)-DOI 塩酸塩
- 别名:
- (±)-DOI 塩酸塩
- 英語名:
- (+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4-
- 英語别名:
- Doi cpd hydrochloride;(+/-)-DOI hydrochloride;Amphetamine Impurity 1 HCl;(+/-)-DOI hydrochloride >=98% (HPLC), solid;(+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4-;DL-2,5-Dimethoxy-4-iodoamphetamine hydrochloride;4-Iodo-2,5-dimethoxyphenylisopropylamine, hydrochloride;(±)-2,5-Dimethoxy-4-Iodoamphetamine hydrochloride solution;4-Iodo-2,5-dimethoxy-α-methylbenzeneethanaminehydrochloride;4-Iodo-2,5-dimethoxy-α-methylbenzeneethanaminehydrochloride
- CBNumber:
- CB8973094
- 化学式:
- C11H16INO2.ClH
- 分子量:
- 357.613
- MOL File:
- 42203-78-1.mol
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(±)-DOI 塩酸塩 物理性質
- 闪点 :
- 9℃
- 貯蔵温度 :
- Store at RT
- 溶解性:
- H2O: 可溶性10mg/mL
- 外見 :
- 個体
- 色:
- ホワイトからオフホワイト
- 水溶解度 :
- Soluble to 50 mM in water
(±)-DOI 塩酸塩 化学特性,用途語,生産方法
一般的な説明
A Certified Spiking Solution
? suited for GC/MS or LC/MS phenethylamine testing applications in forensic analysis, clinical toxicology, or urine drug testing. DOI is a D-substituted amphetamine in the phenethylamine family of hallucinogenic drugs. This designer drug is an extremely potent psychedelic with a long duration of action.
生物活性
Brain penetrant, mixed 5-HT 2A /5-HT 2C receptor agonist (K i values are 0.7, 2.4 and 20 nM for 5-HT 2A , 5-HT 2C and 5-HT 2B receptors respectively). Reduces rapid eye movement (REM) and slow wave sleep and increases waking in the rat. Hallucinogenic agent. Acts via 5-HT 2A receptors to inhibit the inflammatory effects of tumor necrosis factor (TNF)- α .
Biochem/physiol Actions
(±)-DOI hydrochloride is a potent and selective 5-HT2 serotonin receptor agonist that crosses the blood-brain barrier, increases dopamine turnover and the treatment with DOI counteracted the expression of the nicotine-induced locomotor and neurochemical sensitization, but had no effect on nicotine-induced behavioral disinhibition. The responses to DOI provide evidence that of these receptors are abundant in the cortex, and show relatively lower levels in hippocampus and cerebellum.
(±)-DOI 塩酸塩 上流と下流の製品情報
原材料
準備製品
42203-78-1((±)-DOI 塩酸塩)キーワード:
- 42203-78-1
- (+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4-
- 4-Iodo-2,5-dimethoxyphenylisopropylamine, hydrochloride
- Benzeneethanamine, 4-iodo-2,5-dimethoxy-alpha-methyl-, hydrochloride
- Doi cpd hydrochloride
- 4-Iodo-2,5-dimethoxy-α-methylbenzeneethanaminehydrochloride
- BenzeneethanaMine,4-iodo-2,5-diMethoxy-a-Methyl-, hydrochloride (1:1)
- (±)-2,5-Dimethoxy-4-Iodoamphetamine hydrochloride solution
- DL-2,5-Dimethoxy-4-iodoamphetamine hydrochloride
- (+/-)-DOI hydrochloride >=98% (HPLC), solid
- (+/-)-2,5-Dimethoxy-4-Iodoamphetamine hydrochloride solution
- (+/-)-DOI hydrochloride
- 4-Iodo-2,5-dimethoxy-α-methylbenzeneethanaminehydrochloride
- Amphetamine Impurity 1 HCl
- (±)-DOI 塩酸塩