Isonanangenine B
- CAS No.
- 1623153-14-9
- Chemical Name:
- Isonanangenine B
- Synonyms
- Isonanangenine B;(5R,5aS,9R,9aR,9bS)-1,3,5,5a,6,7,8,9,9a,9b-decahydro-9,9b-dihydroxy-6,6,9a-trimethyl-3-oxonaphtho[1,2-c]furan-5-yl ester, hexanoic acid;Hexanoic acid, (5R,5aS,9R,9aR,9bS)-1,3,5,5a,6,7,8,9,9a,9b-decahydro-9,9b-dihydroxy-6,6,9a-trimethyl-3-oxonaphtho[1,2-c]furan-5-yl ester
- CBNumber:
- CB89739369
- Molecular Formula:
- C21H32O6
- Molecular Weight:
- 380.48
- MDL Number:
- MFCD33021275
- MOL File:
- 1623153-14-9.mol
Isonanangenine B Chemical Properties,Uses,Production
Biological Activity
Isonanangenine B is a drimane sesquiterpene lactone that has been found in Aspergillus.1,2 It decreases survivin mRNA expression in a reporter assay when used at concentrations of 13.6, 18.42, and 26.31 μM. Isonanagenine B (18.42 μM) inhibits STAT3 and NF-κB binding to the survivin promoter in chromatin immunoprecipitation (ChIP) assays. It also induces apoptosis in COLO 320DM cells.
References
1.Lacey, H.J., Gilchrist, C.L.M., Crombie, A., et al.Nanangenines: Drimane sesquiterpenoids as the dominant metabolite cohort of a novel Australian fungus, Aspergillus nanangensisBeilstein J. Org. Chem.152631-2643(2019) 2.Felix, S., Sandjo, L.P., Opatz, T., et al.SF002-96-1, a new drimane sesquiterpene lactone from an Aspergillus species, inhibits survivin expressionBeilstein J. Org. Chem.92866-2876(2013)
Isonanangenine B Preparation Products And Raw materials
Raw materials
Preparation Products
Isonanangenine B Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| ChemeGen 中国 | 18818260767 | sales@chemegen.com | China | 6975 | 58 |
| Beijing Biocreative Technology Co., Ltd. | 15522676233 | 3007606172@qq.com | China | 1249 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8740 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.com | China | 24246 | 58 |
| Supplier | Advantage |
|---|---|
| BOC Sciences | 65 |
| ChemeGen 中国 | 58 |
| Beijing Biocreative Technology Co., Ltd. | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |