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Sevelamer hydrochloride

CAS No.
152751-57-0
Chemical Name:
Sevelamer hydrochloride
Synonyms
Sevelemar;SEVELAMER HCL;Sevelamer-001;Tianeptinic acid;SevelaMer HCL API;Sevelamer Hydrochloride;Sevelamer Hydrochloride (100 mg);Sevelamer hydrochloride USP/EP/BP;Sevelamer hydrochloride Impurities;TIANFU-CHEM Sevelamer hydrochloride
CBNumber:
CB91012045
Molecular Formula:
C6H13Cl2NO
Molecular Weight:
186.08
MDL Number:
MOL File:
152751-57-0.mol
MSDS File:
SDS
Last updated:2024-11-19 23:02:33

Sevelamer hydrochloride Properties

storage temp. Store at -20°C
solubility Hot Methanol (Sparingly)
form Solid
color Pale Yellow
FDA UNII GLS2PGI8QG

SAFETY

Risk and Safety Statements

Hazard statements  H412
Precautionary statements  P273-P501

Sevelamer hydrochloride price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC S256000 SevelamerHydrochloride(TechnicalGrade) 152751-57-0 500mg $225 2021-12-16 Buy
AK Scientific E121 Sevelamerhydrochloride 152751-57-0 500mg $225 2021-12-16 Buy
ChemScene CS-3149 Sevelamerhydrochloride >98.0% 152751-57-0 500mg $324 2021-12-16 Buy
ChemScene CS-3149 Sevelamerhydrochloride >98.0% 152751-57-0 100mg $90 2021-12-16 Buy
Product number Packaging Price Buy
S256000 500mg $225 Buy
E121 500mg $225 Buy
CS-3149 500mg $324 Buy
CS-3149 100mg $90 Buy

Sevelamer hydrochloride Chemical Properties,Uses,Production

Originator

Renagel,Chugai Pharmaceutical

Uses

Sevelamer HCl is used in the treatment of hyperphosphataemia in patients suffering from chronic kidney disease.

Uses

Sevelamer hydrochloride is a noncalcemic phosphate binder for the treatment of hyperphosphatemia in chronic renal failure or patients suffering from chronic kidney disease.

Definition

ChEBI: Sevelamer hydrochloride is an epoxide.

Manufacturing Process

Poly(allylamine hydrochloride) (50% w/w, 426 kg) was charged to a 1000 L reactor and water (200 L) was added. Sodium hydroxide solution (32% w/w, 208 kg) was added, followed by 85 L of water. The mixture was stirred for 1 h and filtered to a 2500 L reactor. The transfer line was rinsed with water (217 kg) and acetonitrile (1300 L) added. The temperature was adjusted to 40°C and epichlorohydrin (20 kg) added. The mixture was stirred at 40° to 50°C for 1.5 h and then heated to reflux for 16 h. The resulting product slurry may be isolated and washed in decanter centrifuge.

brand name

Renagel (Genzyme).

Therapeutic Function

Antihyperphosphatemic

Veterinary Drugs and Treatments

Sevalamer may be useful for treating hyperphosphatemia associated with chronic renal failure, particularly when oral aluminum salts are not tolerated.

Sevelamer hydrochloride Preparation Products And Raw materials

Global( 177)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1803 55
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10310 58
Xiamen AmoyChem Co., Ltd
+86-86-5926051114 +8618959220845 sales@amoychem.com China 6383 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17365 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
Hubei Ipure Biology Co., Ltd
+8613367258412 ada@ipurechemical.com China 10319 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
Xi'an MC Biotech, Co., Ltd.
029-89275612 +8618991951683 mcbio_sales@163.com China 2251 58

View Lastest Price from Sevelamer hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Sevelamer hydrochloride pictures 2024-11-19 Sevelamer hydrochloride
152751-57-0
US $30.00-143.00 / mg 10g TargetMol Chemicals Inc.
Sevelamer hydrochloride pictures 2024-01-08 Sevelamer hydrochloride
152751-57-0
US $9.00 / KG 1KG 99% 50000tons Wuhan Boyuan Import & Export Co., LTD
Sevelamer hydrochloride pictures 2023-08-16 Sevelamer hydrochloride
152751-57-0
US $5.00 / kg 1kg >99% 300000ton Weijer International Trade (Hebei) Co., Ltd
SEVELAMER HCL Sevelemar Sevelamer Hydrochloride 2-Propen-1-amine polymer with (chloromethyl)oxirane hydrochloride (ChloroMethyl)oxirane polyMer with 2-Propen-1-aMine Hydrochloride 2-Propen-1-aMine Hydrochloride polyMer with 2-(ChloroMethyl)oxirane AllylaMine Hydrochloride-epichlorohydrin CopolyMer SevelaMer HCL API SevelaMer Hydrochloride DISCONTINUED See : S256000 Sevelamer hydrochloride 2-Propen-1-amine polymer with (chloromethyl)oxirane hydrochloride 2-Propen-1-amine, hydrochloride (1:1), polymer with 2-(chloromethyl)oxirane 2-Propen-1-amine - 2-(chloromethyl)oxirane (1:1) Sevelamer-001 Sevelamer hydrochloride(152751-57-0) Sevelamer hydrochloride USP/EP/BP Sevelamer hydrochloride Impurities Tianeptinic acid TIANFU-CHEM Sevelamer hydrochloride Sevelamer Hydrochloride (100 mg) 152751-57-0 C3H7NmC3H5ClOnHClx C3H7NC3H5ClOHClx C6H12NClO Other APIs Inhibitors Pharmaceutical intermediate Heterocycles Intermediates & Fine Chemicals Pharmaceuticals