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Acetamide, 2-chloro-N-[2-(4-methoxyphenyl)-2H-benzotriazol-5-yl]-

Acetamide, 2-chloro-N-[2-(4-methoxyphenyl)-2H-benzotriazol-5-yl]- structure

CAS No.: 928712-10-1

Chemical Name:: Acetamide, 2-chloro-N-[2-(4-methoxyphenyl)-2H-benzotriazol-5-yl]-

Synonyms: HG106;Acetamide, 2-chloro-N-[2-(4-methoxyphenyl)-2H-benzotriazol-5-yl]-;2-Chloro-N-(2-(4-methoxyphenyl)-2H-benzo[d][1,2,3]triazol-5-yl)acetamide

CBNumber:: CB910258755

Molecular Formula:: C15H13ClN4O2

Molecular Weight:: 316.74

MDL Number:

MOL File:: 928712-10-1.mol

Last updated:2024-07-02 08:55:39

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Acetamide, 2-chloro-N-[2-(4-methoxyphenyl)-2H-benzotriazol-5-yl]- Properties

Density	1.40±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO: 21 mg/mL (66.30 mM);Ethanol: Insoluble
pka	10.89±0.43(Predicted)
form	Solid
color	Off-white to light yellow
Water Solubility	Water: Insoluble

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS05
Signal word	Danger
Hazard statements	H335-H315-H318-H302
Precautionary statements	P264-P280-P302+P352-P321-P332+P313-P362-P280-P305+P351+P338-P310-P264-P270-P301+P312-P330-P501

Acetamide, 2-chloro-N-[2-(4-methoxyphenyl)-2H-benzotriazol-5-yl]- Chemical Properties,Uses,Production

Biological Activity

HG106, a potent SLC7A11 inhibitor, leads to enhanced ROS generation, ER stress, and ultimately growth arrest specifically in KRAS-mutant lung adenocarcinoma (LUAD).

References

[1] Hu K, et al. J Clin Invest. 2020 Apr 1;130(4):1752-1766.

Acetamide, 2-chloro-N-[2-(4-methoxyphenyl)-2H-benzotriazol-5-yl]- Preparation Products And Raw materials

Raw materials

Preparation Products

Acetamide, 2-chloro-N-[2-(4-methoxyphenyl)-2H-benzotriazol-5-yl]- Suppliers

Global( 18)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32760	60
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	13245	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3136	58
Shanghaizehan biopharma technology co., Ltd.	021-61350663 13052117465	sales@zehanbiopharma.com	China	999	55
Shanghai Rechem science Co., Ltd.	21-31433387 15618786686	sales@rechemscience.com	China	2970	58
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	info@SuperLan-chem.com	China	9941	58
DC Chemicals	021-58447131 13564518121	sales@dcchemicals.com	China	9412	58
Changzhou Chenhong Biotechnology Co., Ltd.	0519-85788828 13775037613	sales@chemrenpharm.com	China	3600	58
Guangzhou Younan Technology Co., Ltd	020-020-82000279 18988968278	sales@ubiochem.com	China	4297	58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd	15317229551	15151849396@163.com	China	994	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
Zhengzhou Alfa Chemical Co.,Ltd	58
Nantong HI-FUTURE Biology Co., Ltd.	58
Shanghaizehan biopharma technology co., Ltd.	55
Shanghai Rechem science Co., Ltd.	58
Shanghai Chaolan Chemical Technology Center	58
DC Chemicals	58
Changzhou Chenhong Biotechnology Co., Ltd.	58
Guangzhou Younan Technology Co., Ltd	58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd	58

Acetamide, 2-chloro-N-[2-(4-methoxyphenyl)-2H-benzotriazol-5-yl]- Spectrum

Acetamide, 2-chloro-N-[2-(4-methoxyphenyl)-2H-benzotriazol-5-yl]-(928712-10-1)¹HNMR

Acetamide, 2-chloro-N-[2-(4-methoxyphenyl)-2H-benzotriazol-5-yl]- HG106 2-Chloro-N-(2-(4-methoxyphenyl)-2H-benzo[d][1,2,3]triazol-5-yl)acetamide 928712-10-1