ChemicalBook >> CAS DataBase List >>CAPADENOSON
CAPADENOSON
- CAS No.
- 544417-40-5
- Chemical Name:
- CAPADENOSON
- Synonyms
- CS-1666;BAY 68-4986;CAPADENOSON;Capadenoson, BAY 68-4986;Capadenoson, 10 mM in DMSO;Adenosine Receptor,P1 receptor,Inhibitor,inhibit,Capadenoson;2-Amino-6-[[[2-(4-chlorophenyl)-4-thiazolyl]methyl]thio]-4-[4-(2-hydroxyethoxy)phenyl]-3,5-pyridinedicarbonitrile;2-Amino-6-(((2-(4-chlorophenyl)thiazol-4-yl)methyl)thio)-4-(4-(2-hydroxyethoxy)phenyl)pyridine-3,5-dicarbonitrile;3,5-Pyridinedicarbonitrile, 2-amino-6-[[[2-(4-chlorophenyl)-4-thiazolyl]methyl]thio]-4-[4-(2-hydroxyethoxy)phenyl]-;2-amino-6-[[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methylsulfanyl]-4-[4-(2-hydroxyethoxy)phenyl]pyridine-3,5-dicarbonitrile
- CBNumber:
- CB91092261
- Molecular Formula:
- C25H18ClN5O2S2
- Molecular Weight:
- 520.03
- MDL Number:
- MFCD09954113
- MOL File:
- 544417-40-5.mol
Last updated:2025-01-27 09:38:02
Boiling point | 787.9±70.0 °C(Predicted) |
---|---|
Density | 1.51 |
storage temp. | Store at -20°C |
solubility | Soluble in DMSO |
form | Powder |
pka | 13.98±0.10(Predicted) |
color | Light yellow to yellow |
FDA UNII | O519NVW73R |
UNSPSC Code | 12352200 |
NACRES | NA.77 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS08 |
---|---|
Signal word | Warning |
Hazard statements | H361-H370 |
Precautionary statements | P260-P264-P270-P307+P311-P321-P405-P501-P201-P202-P281-P308+P313-P405-P501 |
CAPADENOSON price More Price(36)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SML2852 | Capadenoson ≥98% (HPLC) | 544417-40-5 | 5MG | $94.2 | 2024-03-01 | Buy |
Sigma-Aldrich | SML2852 | Capadenoson ≥98% (HPLC) | 544417-40-5 | 25MG | $306 | 2024-03-01 | Buy |
Cayman Chemical | 28422 | Capadenoson | 544417-40-5 | 1mg | $49 | 2024-03-01 | Buy |
Cayman Chemical | 28422 | Capadenoson | 544417-40-5 | 10mg | $380 | 2024-03-01 | Buy |
Cayman Chemical | 28422 | Capadenoson | 544417-40-5 | 5mg | $216 | 2024-03-01 | Buy |
CAPADENOSON Chemical Properties,Uses,Production
Biological Activity
Capadenoson (BAY 68-4986) is an adenosine receptor A1 (A1AR) partial agonist (GTPγS binding EC50/Emax = 0.1 nM/74% vs. 0.3 nM/100% with CCPA; human cortex membranes) th at exerts additional biased A2BAR agonism toward cAMP signal transduction (pEC50 = 8.94/cAMP, 6.20/Ca+2, 6.12/pERK, 5.03/IP1), while exhibiting weak A2A & A3 potency. Capadenoson offers cardioprotection efficacy in an ischemia-reperfusion injury r at model in vivo (25/28% infarct size reduction with 0.1/0.3 mg/kg iv.) without the risk of a full atrioventricular (AV) block (isolated perfused r at heart rate = 100% up to 10 nM, 90% at ≥10 μM) seen with the full A1 agonist CCPA.
target
adenosine A1 receptor
CAPADENOSON Preparation Products And Raw materials
Raw materials
Preparation Products
CAPADENOSON Suppliers
Global( 76)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32965 | 60 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29810 | 58 |
Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 | gksales1@gk-bio.com | China | 9310 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24727 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
TargetMol Chemicals Inc. | support@targetmol.com | United States | 38631 | 58 | |
Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
View Lastest Price from CAPADENOSON manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-11-19 | Capadenoson
544417-40-5
|
US $35.00-109.00 / mg | 99.62% | 10g | TargetMol Chemicals Inc. | ||
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2021-07-13 | Capadenoson
544417-40-5
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
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2021-07-09 | Capadenoson
544417-40-5
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- Capadenoson
544417-40-5
- US $35.00-109.00 / mg
- 99.62%
- TargetMol Chemicals Inc.
-
- Capadenoson
544417-40-5
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- Capadenoson
544417-40-5
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
544417-40-5(CAPADENOSON)Related Search:
BAY 68-4986
Capadenoson, BAY 68-4986
CAPADENOSON
2-Amino-6-[[[2-(4-chlorophenyl)-4-thiazolyl]methyl]thio]-4-[4-(2-hydroxyethoxy)phenyl]-3,5-pyridinedicarbonitrile
2-amino-6-[[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methylsulfanyl]-4-[4-(2-hydroxyethoxy)phenyl]pyridine-3,5-dicarbonitrile
CS-1666
3,5-Pyridinedicarbonitrile, 2-amino-6-[[[2-(4-chlorophenyl)-4-thiazolyl]methyl]thio]-4-[4-(2-hydroxyethoxy)phenyl]-
2-Amino-6-(((2-(4-chlorophenyl)thiazol-4-yl)methyl)thio)-4-(4-(2-hydroxyethoxy)phenyl)pyridine-3,5-dicarbonitrile
Adenosine Receptor,P1 receptor,Inhibitor,inhibit,Capadenoson
Capadenoson, 10 mM in DMSO
544417-40-5
C25H18ClN5O2S2