Pirinixil
- CAS No.
- 65089-17-0
- Chemical Name:
- Pirinixil
- Synonyms
- Pirinixil;2-[[4-Chloro-6-(2,3-dimethylphenylamino)-2-pyrimidinyl]thio]-N-(2-hydroxyethyl)acetamide;2-[[4-Chloro-6-[(2,3-dimethylphenyl)amino]pyrimidin-2-yl]thio]-N-(2-hydroxyethyl)acetamide;Acetamide, 2-[[4-chloro-6-[(2,3-dimethylphenyl)amino]-2-pyrimidinyl]thio]-N-(2-hydroxyethyl)-
- CBNumber:
- CB91117302
- Molecular Formula:
- C16H18ClN3OS
- Molecular Weight:
- 366.87
- MDL Number:
- MFCD00869091
- MOL File:
- 65089-17-0.mol
- MSDS File:
- SDS
| Melting point | 145°C |
|---|---|
| Boiling point | 609.6±55.0 °C(Predicted) |
| Density | 1.2894 (rough estimate) |
| refractive index | 1.6100 (estimate) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| pka | 13.27±0.46(Predicted) |
| FDA UNII | 969LVT6GJ2 |
Pirinixil Chemical Properties,Uses,Production
Uses
Pirinixil, is an absorbable hypolipidemic agent of low toxicity.
Safety Profile
Suspected carcinogen with experimental carcinogenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of Cl-, NOx and SOx
in vivo
Pirinixil is a hypolipidemic agent of low toxicity. Total cholesterol is reduced by Pirinixi in the spleen, kidney and heart of rats. Pirinixil decreases the estimated total body cholesterol approximately 40%[1]. Pirinixil increases plasma cholesterol levels significantly without affecting plasma triglycerides. Liver cholesterol and triglycerides are markedly reduced by Pirinixil, while combined plasma and liver lipid levels decrease approximately 20%. Liver HMG-CoA reductase activity is not affected, but cholesterol 7α-hydroxylase is significantly reduced by Pirinixil[2].
Pirinixil Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38630 | 58 | |
| TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19881 | 58 |
| Shanghai Synchem Pharma Co., ltd | 21-619849051-1 18521059765 | synchempharma@aliyun.com | China | 6466 | 55 |
| Angel Pharmatech, Ltd. | 17317130613 | 3358272972@qq.com | China | 3259 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29774 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24641 | 58 |
| Adooq Bioscience LLC | 400-025-6535 | sales@adooq.cn | China | 18215 | 58 |
