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AIDS124653

AIDS124653 Structure
AIDS124653 structure
CAS No.
26903-26-4
Chemical Name:
AIDS124653
Synonyms
NSC43067;NSC 43067;AIDS124653;NSC43067 >=98% (HPLC);1-(5-Methyl-thiophen-2-yl)-3-phenyl-propenone;1-(5-Methyl-2-thienyl)-3-phenyl-2-Propen-1-one;2-Propen-1-one, 1-(5-methyl-2-thienyl)-3-phenyl-
CBNumber:
CB91244743
Molecular Formula:
C14H12OS
Molecular Weight:
228.31
MDL Number:
MFCD00489751
MOL File:
26903-26-4.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06
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AIDS124653 Properties

Boiling point 379.8±42.0 °C(Predicted)
Density 1.167±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: >20mg/mL
form powder
color light yellow to light tan

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H413
Precautionary statements  P264-P270-P273-P301+P312-P501

AIDS124653 price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich N0915 NSC43067 ≥98% (HPLC) 26903-26-4 25mg $675 2024-03-01 Buy
Sigma-Aldrich N0915 NSC43067 ≥98% (HPLC) 26903-26-4 5mg $150 2022-05-15 Buy
American Custom Chemicals Corporation KIN0001259 NSC43067 95.00% 26903-26-4 1G $754.95 2021-12-16 Buy
Product number Packaging Price Buy
N0915 25mg $675 Buy
N0915 5mg $150 Buy
KIN0001259 1G $754.95 Buy

AIDS124653 Chemical Properties,Uses,Production

Biochem/physiol Actions

NSC43067 is a Cyclin-dependent kinase (Cdk) inhibitor which binds to a novel conserved site on Cdk, presumably the p27 binding pocket. The binding apparently directly induces Cdk1, Cdk2, and Cdk4 protein aggregation. Cdks 1, 2, 4, and 6 are the key Cdks that regulate the cell cycle, and are a target for a cancer treatment. NSC43067 arrests the cell cycle at the G0/G1 phase at lower concentrations and at the G2/M cell cycle phase at higher concentrations. The action appears to be reversible.

AIDS124653 Preparation Products And Raw materials

Raw materials

Preparation Products

AIDS124653 Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44918 58
Supplier Advantage
Energy Chemical 58
AIDS124653 1-(5-Methyl-2-thienyl)-3-phenyl-2-Propen-1-one 1-(5-Methyl-thiophen-2-yl)-3-phenyl-propenone NSC 43067 NSC43067 NSC43067 >=98% (HPLC) 2-Propen-1-one, 1-(5-methyl-2-thienyl)-3-phenyl- 26903-26-4