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Bacitracin zinc

CAS No.
1405-89-6
Chemical Name:
Bacitracin zinc
Synonyms
ZINC BACITRACIN;ZINC BACITRACIN USP;BACITRACIN ZINC SALT;Albac;Noptracin;Baciferm PB;Bacitracine;Bacitracinzink;BACITRACIN ZINC;BACITRACIN ZINC
CBNumber:
CB9127618
Molecular Formula:
C66H101N17O16SZn
Molecular Weight:
1486.06744
MDL Number:
MFCD28168035
MOL File:
1405-89-6.mol
Last updated:2024-12-18 14:15:30

Bacitracin zinc Properties

Melting point 250 °C (dec.)
storage temp. 2-8°C
solubility 10 mM HCl: 5 mg/mL, clear, faintly yellow-green
form Fine Crystalline Powder
color White to light yellow-gray or beige
PH Shake 1.0 g with 10 mL of carbon-dioxide-free water R and filter; pH of the filtrate, 6.0-7.5.
Water Solubility 5.1 g/L (28 ºC)
Merck 13,938
InChIKey UCRLQOPRDMGYOA-FWMPYRTHSA-L
LogP -1.852 (est)
FDA 21 CFR 558.78; 558.4
EWG's Food Scores 1
FDA UNII 89Y4M234ES
EPA Substance Registry System Zinc bacitracin (1405-89-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319-H412-H317-H335-H315
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P273-P501-P264-P280-P305+P351+P338-P337+P313P-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501
Safety Statements  22-24/25
WGK Germany  3
3
HS Code  29419090
NFPA 704
0
2 0

Bacitracin zinc price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich B5150 Bacitracin zinc salt from Bacillus licheniformis, ~70,000?U/g 1405-89-6 250000units $65.8 2024-03-01 Buy
Sigma-Aldrich B5150 Bacitracin zinc salt from Bacillus licheniformis, ~70,000?U/g 1405-89-6 1250000units $225 2024-03-01 Buy
Sigma-Aldrich B8800 Bacitracin zinc salt from Bacillus licheniformis, meets USP testing specifications 1405-89-6 50000units $52.3 2023-01-07 Buy
Sigma-Aldrich B8800 Bacitracin zinc salt from Bacillus licheniformis, meets USP testing specifications 1405-89-6 1250000units $229 2022-05-15 Buy
Cayman Chemical 21212 Bacitracin (zinc) ≥70% (Bacitracin A,B1,B3 mixture) 1405-89-6 1g $26 2024-03-01 Buy
Product number Packaging Price Buy
B5150 250000units $65.8 Buy
B5150 1250000units $225 Buy
B8800 50000units $52.3 Buy
B8800 1250000units $229 Buy
21212 1g $26 Buy

Bacitracin zinc Chemical Properties,Uses,Production

what is bacitracin zinc used for

Bacitracin zinc is bacitracin and zinc ions to form complexes, which is a polypeptide antibiotic, is one of the most widely used antibiotics in feed additives, zinc content is 2%~12%. synthetic product is white or yellowish powder, with special odor, deliquescent alkaline substance, soluble in water, methanol and ethanol. Bacitracin zinc has strong antibacterial effect against gram positive bacteria, also has antibacterial properties of some gram negative bacteria. The use of bacitracin zinc in pig feed, can promote growth, improve feed, prevention and treatment of swine bacterial diarrhea and chronic respiratory diseases. The concentration of 10 in general to 100mg/kg, more than the addition range of effect was not improved obviously. Bacitracin zinc in swine intestine is not generally absorbed, so there is no problem, is a reliable and safe antibiotic additives. Bacitracin zinc toxicity is strong, and not easy to be absorbed, it can not be used as a systemic infection treatment.

Biological functions

Bacitracin zinc is a medicine applied to cuts and other skin wounds to help prevent infection. bacitracin is a germ-killing medicine called an antibiotic. peptide antibiotics have a strong antibacterial effect on the gram positive bacteria, also has antibacterial effect to a small number of Gram-negative bacteria, and the spiral and actinomycetes and resistant to penicillin resistant Staphylococcus aureus.The antibacterial mechanism inhibits for the formation of damage and bacterial cell wall. The bacterial cytoplasmic membrane can promote beneficial intestinal microbial growth, increased intestinal permeability, promote the absorption of nutrients. Mainly used to promote the growth of livestock and poultry, livestock and poultry as well as prevention and treatment of bacterial diarrhea caused by Treponema pig dysentery. Oral administration of bacitracin zinc is almost no absorption, mostly in 2 days with the feces. So it is not easy to remain in the livestock and poultry products; bacteria to bacitracin produced very little resistance, and other antibiotics nor cross resistance and with penicillin, streptomycin, neomycin, streptomycin, mostly clay bacteria and have a synergistic effect. This product is toxic, not injection. The goods and olaquindox, guitar mold, mold of Virginia, Pinella mildew element existence is incompatibility.

Uses

1. Bacitracin zinc is used as feed additive for promoting the growth of livestock and poultry, prevention and treatment of livestock and poultry bacterial diarrhea and dense helicoid is caused by blood dysentery. Oral administration of zinc bacitracin is almost no absorption, mostly in 2 days with the feces. So it is not easy to remain in the livestock and poultry products; bacteria to bacitracin produced very little resistance, and other antibiotics nor cross resistance and with penicillin, streptomycin, neomycin, streptomycin, mostly clay bacteria and have a synergistic effect. This product is toxic, not injection. The goods and olaquindox, guitar mold, mold of Virginia, Pinella mildew element existence is incompatibility.
2. Bacitracin zinc is a polypeptide antibiotic, against gram positive bacteria with a bactericidal effect, its mechanism is mainly inhibiting the synthesis of bacterial cell wall of bacteria, can also with sensitive bacteria cell membrane combined injury of cell membrane integrity, resulting in cells of the important materials in the outflow. Effectively inhibit gram positive bacteria and some gram negative bacteria; bacteria on resistance of bacitracin zinc slower, and other antibiotics without cross resistance.
3. Peptide antibiotics, can inhibit the phosphorylation of pyrophosphate lipid, thereby inhibiting the synthesis of bacterial cell walls.

Description

Bacitracin zinc is a zinc complex of bacitracin, a polypeptide produced by the growth of an organism of the licheniformis group of Bacillus subtilis. The main components are Bacitracin A, B1 and B2.Bacitracin zinc has antibiotic activity against a variety of Gram-positive bacteria including staphylococci. The zinc complex adds stability to the component, making bacitracin zinc more stable compared to bacitracin.

Chemical Properties

a white or pale brownish yellow powder; odourless or with a faint characteristic odour. Soluble in 900 parts of water and in 500 parts of ethanol (~750 g/l) TS; very slightly soluble in ether R. small amounts of bacitracin zinc are dissolved in petroleum jelly to create antibiotic ointments.

Uses

Bacitracin zinc is a dephosphorylation of the C55-isoprenyl pyrophosphate interference for inhibition of cleavage of Tyr from Met-enkephalin with IC50 of 10 μM.

Indications

Bacitracin zinc is composed of a group of polypeptides with antibiotic activity against a variety of Gram-positive bacteria including staphylococci. It is used in the treatment of local infections, mainly infections of the skin, ear and eye.

brand name

Ziba (X Gen).

storage

Bacitracin zinc should be kept in a tightly closed container, protected from light, and stored at a temperature not exceeding 25 °C. If it is intended for parenteral administration, the container should be sterile and sealed so as to exclude microorganisms.

Bacitracin zinc Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 372)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Weibang Biotechnology Co., Ltd
+8615531157085 abby@weibangbio.com China 8807 58
Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578 sales@hbmojin.com China 12834 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325 sales1@chuanghaibio.com China 5889 58
Henan Bao Enluo International TradeCo.,LTD
+86-17331933971 +86-17331933971 deasea125996@gmail.com China 2472 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618092446649 sarah@tnjone.com China 1143 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 - 03@ sales03@shyrchem.com CHINA 738 60
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +8618949832763 info@tnjchem.com China 2986 55
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29880 58
Shaanxi Yikanglong Biotechnology Co., Ltd.
17791478691 yklbiotech@163.com CHINA 296 58

View Lastest Price from Bacitracin zinc manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Zinc Bacitracin pictures 2024-12-24 Zinc Bacitracin
1405-89-6
US $0.00 / Kg/Bag 2Kg/Bag 99% up, High Density 20 tons Sinoway Industrial co., ltd.
Bacitracin zinc pictures 2024-12-13 Bacitracin zinc
1405-89-6
US $0.00-0.00 / Kg/Drum 1KG ≥65IU/mg; USP40 2000kg/month WUHAN FORTUNA CHEMICAL CO., LTD
Bacitracin Zinc pictures 2024-11-19 Bacitracin Zinc
1405-89-6
US $36.00-56.00 / mg 63.98% 10g TargetMol Chemicals Inc.
  • Zinc Bacitracin pictures
  • Zinc Bacitracin
    1405-89-6
  • US $0.00 / Kg/Bag
  • 99% up, High Density
  • Sinoway Industrial co., ltd.
  • Bacitracin zinc pictures
  • Bacitracin zinc
    1405-89-6
  • US $0.00-0.00 / Kg/Drum
  • ≥65IU/mg; USP40
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • Bacitracin Zinc pictures
  • Bacitracin Zinc
    1405-89-6
  • US $36.00-56.00 / mg
  • 63.98%
  • TargetMol Chemicals Inc.
BACITRACIN ZINC BACITRACIN ZINC 4-[2-[[2-(1-AMINO-2-METHYL-BUTYL)-4,5-DIHYDRO-1,3-THIAZOL-4-YL]CARBONYLAMINO]-4-METHYL-PENTANOYL]AMINO-5-[1-[[18-(3-AMINOPROPYL)-12-BENZYL-15-BUTAN-2-YL-3-(CARBAMOYLMETHYL)-6-(CARBOXYMETHYL)-9-(4H-IMIDAZOL-4-YLMETHYL)-2,5,8,11,14,17,20-HEPTAOXO-1,4,7,10,13,16,19-HEPTAZACYCLOPENTACOS-21-YL]CARBAMOYL]-2-METHYL-BUTYL]AMINO-5-OXO-PENTANOIC ACID, ZINC Albac Baciferm PB Noptracin Polymyxin B Sulfate bacitracin zinc Bacitracin, zinc saltZinc bacitracin BACITRACIN ZINC SALT USP Bacitracin Zinc salt from Bacillus sp. BACITRACIN U.S.P. ACTIVITY: 60 UNITS/MG MINIMUM ZINC SALT Bacitracinzink BACITRACINE ZINC Bacitracin Zinc USP Bacitracin, zinc salt, potency min. 60 Units/mg bacitracin zinc salt from bacillus licheniformis BACITRACINZINC,MICRONIZED BACITRACINZINC,MICRONIZED,USP Methylprednisolone, Micronized Bacitracin zine Bacitracin Zinc (200 mg) ZIBA-RX (bacitracin zinc) Zinc bacitracin Bacitracin zinc salt Bacitracin zinc salt,>=70 U/Mg Zinc Bacitracin(USP35) Zinc bacitracin In stock GMP Factory Bacitracin zinc salt, from Bacillus licheniformis, ~70,000 U/g Bacitracin zinc CRS Bacitracin for system suitability Bacitracin zinc saL BACITRACIN ZINC 15% Zinc bacitracin USP/EP/BP Bacitracin Zinc (>80%) Bacitracin-ZincQ: What is Bacitracin-Zinc Q: What is the CAS Number of Bacitracin-Zinc Q: What is the storage condition of Bacitracin-Zinc Q: What are the applications of Bacitracin-Zinc Bacitracin Zinc (1048007) Bacitracin zinc, >40 U/mg Bacilli peptide zinc Bacitracin zinc salt, >=60 units/mg BACITRACIN ZNIC zinc 5-[[1-[[15-(3-aminopropyl)-12-butan-2-yl-3-(carboxylatomethyl)-6-(1H-imidazol-5-ylmethyl)-2,5,8,11,14,17-hexaoxo-9-(phenylmethyl)-1,4,7,10,13,16-hexazacyclodocos-18-yl]amino]-3-methyl-1-oxopentan BACITRACIN ZINC SALT ZINC BACITRACIN ZINC BACITRACIN USP Bacitracine 1405-89-6 C66H101N17O16SZn C66H103O16N17S 148606 C66H103N17O16SZn BioChemical Antibiotics A to Z Antibiotics A-F Antibiotics Steroids Veterinaries API intermediates pharmaceutical raw material APIs