4-Benzylpiperidine
- CAS No.
- 31252-42-3
- Chemical Name:
- 4-Benzylpiperidine
- Synonyms
- NSC 30346;AKOS BBS-00003617;4-Benzylpiperdine;4-benzyl-piperidin;4-BENZYLPIPERIDINE;Piperidine, 4-benzyl-;4-Benzylpiperidine99%;LABOTEST-BB LTBB000752;4-Benzylpiperidine,98%;4-Benzylpiperidine >
- CBNumber:
- CB9141122
- Molecular Formula:
- C12H17N
- Molecular Weight:
- 175.27
- MDL Number:
- MFCD00006006
- MOL File:
- 31252-42-3.mol
- MSDS File:
- SDS
Melting point | 6-7 °C (lit.) |
---|---|
Boiling point | 279 °C (lit.) |
Density | 0.997 g/mL at 25 °C (lit.) |
refractive index |
n |
Flash point | >230 °F |
storage temp. | Store below +30°C. |
form | Viscous Liquid |
pka | 10.58±0.10(Predicted) |
color | Clear colorless to yellow |
BRN | 132339 |
CAS DataBase Reference | 31252-42-3(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | JDF1T4667S |
EPA Substance Registry System | Piperidine, 4-(phenylmethyl)- (31252-42-3) |
4-Benzylpiperidine price More Price(25)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 142360 | 4-Benzylpiperidine 99% | 31252-42-3 | 25g | $57.2 | 2024-03-01 | Buy |
TCI Chemical | B0387 | 4-Benzylpiperidine >99.0%(GC) | 31252-42-3 | 25mL | $32 | 2022-04-27 | Buy |
TCI Chemical | B0387 | 4-Benzylpiperidine >99.0%(GC) | 31252-42-3 | 250mL | $198 | 2021-12-16 | Buy |
Alfa Aesar | B23883 | 4-Benzylpiperidine, 98% | 31252-42-3 | 100g | $91.3 | 2021-12-16 | Buy |
Alfa Aesar | B23883 | 4-Benzylpiperidine, 98% | 31252-42-3 | 25g | $34.1 | 2021-12-16 | Buy |
4-Benzylpiperidine Chemical Properties,Uses,Production
Chemical Properties
clear colourless to yellow viscous liquid.
Uses
4-Benzylpiperidine was studied as acid corrosion inhibitor for iron. It was also used to study potential utility of dopamine-welective releaser as a treatment for cocaine dependence. In an assay of cocaine discrimination, 4-Benzylpiperidine had the most rapid onset and shortest duration of action.
Preparation
4-Benzylpiperidine can be prepared by reacting 4-cyanopyridine with toluene. Catalytic hydrogenation of the pyridine ring then completes the synthesis.
Application
Reactant for synthesis of:
Antiproliferatives
GABA uptake inhibitors
Pyridines
Histamine H3 antagonists
Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer′s and neuronal vascular diseases
Antiserotoninergic, antiplatelet, hemorheologic, antiarrythmic and antioxidant molecules via nucleophilic substitution
Synthesis Reference(s)
Synthesis, p. 741, 1980 DOI: 10.1055/s-1980-29196
General Description
4-Benzylpiperidine is dopamine-selective releaser. It is a potential candidate for treatments for cocaine dependence.
Biochem/physiol Actions
4-Benzylpiperidine inhibits the activity of rat brain monoamine oxidase-A and -B, with IC50 values of 0.02 mM and 2 mM respectively. It acts as a monoamine releasing agent with 20- to 48-fold selectivity for releasing dopamine versus serotonin. It is most efficacious as a releaser of norepinephrine, with an ec50 of 109/41.4/5246nM for DA/NE/5HT, respectively . It has a fast onset of action and a short duration. It also functions as a monoamine oxidase inhibitor (MAOI) with preference for MAO-A.
4-Benzylpiperidine Preparation Products And Raw materials
Raw materials
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Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Xi'an MC Biotech, Co., Ltd. | 029-89275612 +8618991951683 | mcbio_sales@163.com | China | 2255 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 | info@edengenechem.com | China | 2169 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29825 | 58 |
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21149 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34571 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
View Lastest Price from 4-Benzylpiperidine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2020-02-26 | 4-Benzylpiperidine
31252-42-3
|
US $0.00-0.00 / Kg | 100G | 99.0%+ | 100 tons | Shaanxi Dideu Medichem Co. Ltd | |
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2020-01-03 | 4-BENZYLPIPERIDINE
31252-42-3
|
US $9.80 / KG | 1g | ≥99% | 100kg | Career Henan Chemical Co |
-
- 4-Benzylpiperidine
31252-42-3
- US $0.00-0.00 / Kg
- 99.0%+
- Shaanxi Dideu Medichem Co. Ltd
-
- 4-BENZYLPIPERIDINE
31252-42-3
- US $9.80 / KG
- ≥99%
- Career Henan Chemical Co
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