ChemicalBook >> CAS DataBase List >>2-Hydroxy-3-trifluoromethylpyridine
2-Hydroxy-3-trifluoromethylpyridine
- CAS No.
- 22245-83-6
- Chemical Name:
- 2-Hydroxy-3-trifluoromethylpyridine
- Synonyms
- 3-Trifluoromethyl-pyridin-2-ol;2-HYDROXY-3-(TRIFLUOROMETHYL)PYRIDINE;BUTTPARK 24\01-66;2-Hydroxy-3-(trifL;2-Hydroxy-3-trifluor;Hydroxy-3-trifluoromethyl;2-Hydroxy-3-trifluoromethyl;3-trifluoroMethyl-2-pyridinol;3-(TRIFLUOROMETHYL)-2-PYRIDONE;3-(Trifluoromethyl)-2-pyridinone
- CBNumber:
- CB9168839
- Molecular Formula:
- C6H4F3NO
- Molecular Weight:
- 163.1
- MDL Number:
- MFCD00153194
- MOL File:
- 22245-83-6.mol
- MSDS File:
- SDS
Last updated:2024-11-05 19:05:58
| Melting point | 150-153°C |
|---|---|
| Boiling point | 223.7±40.0 °C(Predicted) |
| Density | 1.398±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| form | powder to crystal |
| pka | 9.67±0.10(Predicted) |
| color | White to Almost white |
| InChI | InChI=1S/C6H4F3NO/c7-6(8,9)4-2-1-3-10-5(4)11/h1-3H,(H,10,11) |
| InChIKey | JHDCDEHVUADNKQ-UHFFFAOYSA-N |
| SMILES | C1(=O)NC=CC=C1C(F)(F)F |
| LogP | 0.71 at 25℃ |
| CAS DataBase Reference | 22245-83-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,Xn,T | |||||||||
| Risk Statements | 36/37/38-65-20/21/22-20/21-36-25 | |||||||||
| Safety Statements | 26-36/37/39-36-45 | |||||||||
| RIDADR | UN2811 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29333990 | |||||||||
| NFPA 704 |
|
2-Hydroxy-3-trifluoromethylpyridine price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | T2600 | 3-(Trifluoromethyl)-2-pyridone >98.0%(GC)(T) | 22245-83-6 | 1g | $45 | 2024-03-01 | Buy |
| TCI Chemical | T2600 | 3-(Trifluoromethyl)-2-pyridone >98.0%(GC)(T) | 22245-83-6 | 5g | $141 | 2024-03-01 | Buy |
| TRC | H971565 | 2-Hydroxy-3-trifluoromethylpyridine | 22245-83-6 | 1g | $70 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4H01-3-23 | 2-Hydroxy-3-(trifluoromethyl)pyridine 98% | 22245-83-6 | 25g | $60 | 2021-12-16 | Buy |
| Apolloscientific | PC4868W | 2-Hydroxy-3-(trifluoromethyl)pyridine 97% | 22245-83-6 | 100g | $65 | 2021-12-16 | Buy |
2-Hydroxy-3-trifluoromethylpyridine Chemical Properties,Uses,Production
Description
2-hydroxy-3-(trifluoromethyl)pyridine (or 3-(Trifluoromethyl)-2-pyridone) is a trifluoromethyl substituted 2-hydroxypyridine. It is used as a synthesis intermediate for ligands and bioactive ingredients in the application of drug discovery and catalytic reactions. In catalytic reactions, the amide group of 2-pyridone binds to transition metals, forming stable 5-/6-membered ring intermediates. Hence, 2-hydroxy-3-(trifluoromethyl)pyridine is widely used as a ligand in catalytic reactions such as directed C-H activation on meta-position. In addition, the trifluoromethyl substituent of 3-(trifluoromethyl)-2-pyridone tunes its metal-binding affinity and limits the reaction site for improving regioselectivity.
Chemical Properties
White powder
Uses
2-Hydroxy-3-trifluoromethylpyridine is a reactant in the synthesis of Pyrido[2,3-b]pyrazine, a TRPV1 antagonist .
2-Hydroxy-3-trifluoromethylpyridine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 356)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5857 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | bess@weibangbio.com | China | 18153 | 58 |
| PNP Biotech Co. Ltd | +8618516098983 | sales@pnpbiotech.com | China | 1001 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 615 | 58 |
| SHANDONG OUCHEM CO.,LTD. | +86-18506360988 +86-18506360988 | wtaili@ouchem.cn | China | 51 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Springchem New Material Technology Co.,Limited | +86-021-62885108 +8613917661608 | info@spring-chem.com | China | 2068 | 57 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Hi-Tech Chemistry Corp | 0519-86626038 | yuhh@hitechem.com | CHINA | 810 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
View Lastest Price from 2-Hydroxy-3-trifluoromethylpyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-05 | 2-Hydroxy-3-trifluoromethylpyridine
22245-83-6
|
US $30.00-10.00 / KG | 50KG | 99% | 500000kg | Hebei Weibang Biotechnology Co., Ltd | |
 |
2024-11-05 | 2-Hydroxy-3-trifluoromethylpyridine
22245-83-6
|
US $0.00-0.00 / kg | 1kg | 99% Min. | 10000KG | SHANDONG OUCHEM CO.,LTD. | |
 |
2024-11-04 | 2-Hydroxy-3-trifluoromethylpyridine
22245-83-6
|
US $0.00 / gm | 100gm | 99%min | 100kgs | Shanghai Yongzeng Technology Co.,Ltd |
-
- 2-Hydroxy-3-trifluoromethylpyridine
22245-83-6
- US $30.00-10.00 / KG
- 99%
- Hebei Weibang Biotechnology Co., Ltd
-
- 2-Hydroxy-3-trifluoromethylpyridine
22245-83-6
- US $0.00-0.00 / kg
- 99% Min.
- SHANDONG OUCHEM CO.,LTD.
-
- 2-Hydroxy-3-trifluoromethylpyridine
22245-83-6
- US $0.00 / gm
- 99%min
- Shanghai Yongzeng Technology Co.,Ltd
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2-Hydroxy-3-trifluoromethylpyridine 22245-83-6
2-HYDROXY-3-(TRIFLUOROMETHYL)PYRIDINE
3-Trifluoromethyl-pyridin-2-ol
2-Hydroy-3-trifluoromethylpyridine
3-(Trifluoromethyl)-2(1H)-pyridinone
Hydroxy-3-trifluoromethyl
22245-83-6
33252-63-1
Fluorine series
blocks
FluoroCompounds
Pyridines
Pyridine