4-Chloro-2,6-diaminopyrimidine
- CAS No.
- 156-83-2
- Chemical Name:
- 4-Chloro-2,6-diaminopyrimidine
- Synonyms
- 2,4-DIAMINO-6-CHLOROPYRIMIDINE;6-CHLORO-PYRIMIDINE-2,4-DIAMINE;NSC 8818;JACS-156-83-2;TIMTEC-BB SBB004123;4-Chloro-2,6-diamino;DiaMino-6-chloropyriMid;Minoxidil EP Impurity B;Minoxidil EP Impurity 3;oro-2,6-diaminopyrimidine
- CBNumber:
- CB9194300
- Molecular Formula:
- C4H5ClN4
- Molecular Weight:
- 144.56
- MDL Number:
- MFCD00006097
- MOL File:
- 156-83-2.mol
- MSDS File:
- SDS
Melting point | 199-202 °C(lit.) |
---|---|
Boiling point | 199-202 °C |
Density | 1.3966 (rough estimate) |
vapor pressure | 0.0±1.1 mmHg at 25°C |
refractive index | 1.702 |
Flash point | 218.9±29.6 °C |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | slightly soluble |
pka | 3.66±0.10(Predicted) |
form | Solid |
color | White to Pale Yellow |
Water Solubility | slightly soluble |
BRN | 118455 |
InChI | InChI=1S/C4H5ClN4/c5-2-1-3(6)9-4(7)8-2/h1H,(H4,6,7,8,9) |
InChIKey | QJIUMVUZDYPQRT-UHFFFAOYSA-N |
SMILES | C1(N)=NC(Cl)=CC(N)=N1 |
CAS DataBase Reference | 156-83-2(CAS DataBase Reference) |
FDA UNII | 83NU5F7ZAS |
NIST Chemistry Reference | Pyrimidine, 6-chloro-2,4-diamino-(156-83-2) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xn,Xi | |||||||||
Risk Statements | 22-36/37/38 | |||||||||
Safety Statements | 26-24/25 | |||||||||
WGK Germany | 3 | |||||||||
Hazard Note | Irritant | |||||||||
HS Code | 29335995 | |||||||||
NFPA 704 |
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4-Chloro-2,6-diaminopyrimidine price More Price(27)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | C33204 | 2,6-Diamino-4-chloropyrimidine 98% | 156-83-2 | 5g | $53.3 | 2024-03-01 | Buy |
Sigma-Aldrich | C33204 | 2,6-Diamino-4-chloropyrimidine 98% | 156-83-2 | 25g | $166 | 2024-03-01 | Buy |
TCI Chemical | C0811 | 6-Chloro-2,4-diaminopyrimidine >98.0%(GC)(T) | 156-83-2 | 25g | $58 | 2024-03-01 | Buy |
Alfa Aesar | A17780 | 2,4-Diamino-6-chloropyrimidine, 98% | 156-83-2 | 25g | $0 | 2021-12-16 | Buy |
Alfa Aesar | A17780 | 2,4-Diamino-6-chloropyrimidine, 98% | 156-83-2 | 5g | $38.8 | 2021-12-16 | Buy |
4-Chloro-2,6-diaminopyrimidine Chemical Properties,Uses,Production
Chemical Properties
White Cyrstalline Solid
Uses
Definition
ChEBI: 6-chloro-2,4-pyrimidinediamine (4-Chloro-2,6-diaminopyrimidine) is a member of pyrimidines and an organohalogen compound.
Synthesis
2,4-Diamino-6-hydroxypyrimidine (1.00 g, 7.93 mmol) was added to POCl3 (9 mL) and stirred at 97 ℃ for 17 h. The reaction solution was added to ice water slowly and then stirred at 90 C for 1 h. The pH of this solution was adjusted to 8 with NaOH, and then it was extracted with EtOAC (150 mL 3). The combined organic layers were dried with Na2SO4, filtered, and concentrated to give white solid 4-Chloro-2,6-diaminopyrimidine 0.97 g, yielding 85%.
Purification Methods
It recrystallises from boiling H2O (charcoal) as needles; it also crystallises from Me2CO. [Büttner Chem Ber 36 2232 1903, Roth J Am Chem Soc 72 1914 1950, UV: Brown & Jacobsen J Chem Soc 3172 1962, Beilstein 24 H 318, 25 III/IV 2788.]
4-Chloro-2,6-diaminopyrimidine Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Guangzhou Tosun Pharmaceutical Limited | +8618922120635 | sales@toref-standards.com | China | 1000 | 58 |
Zhengzhou Lingzhiyue Technology Co., Ltd | +86-0371-55074660 +86-13783527580 | Lingzhiyue@aliyun.com | China | 3152 | 58 |
Zhejiang Kinso Technology Co., LTD. | +8619857958369 | sales@kinsopharma.com | China | 47 | 58 |
Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2967 | 58 |
Hebei Guanlang Biotechnology Co,.LTD | +86-19930503253; +8619930503252 | daisy@crovellbio.com | China | 5831 | 58 |
Zhengzhou Anbu Chem Co.,Ltd | +86-0371-88006763; +8615988602810 | sales@anbuchem.com | China | 3000 | 58 |
Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 994 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20296 | 58 |
hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | sales03@chemcn.cn | China | 973 | 58 |
Hebei Mojin Biotechnology Co.,Ltd | +8613288715578 | angelia@hbmojin.com | China | 764 | 58 |
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View Lastest Price from 4-Chloro-2,6-diaminopyrimidine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2024-08-16 | 4-Chloro-2,6-diaminopyrimidine
156-83-2
|
US $20.00 / kg | 1kg | 99% | 2000kg | hebei hongtan Biotechnology Co., Ltd | |
![]() |
2024-08-16 | 4-Chloro-2,6-diaminopyrimidine
156-83-2
|
US $5.00 / kg | 1kg | ≥99% | 1000mt/year | Jinan Finer Chemical Co., Ltd | |
![]() |
2024-08-15 | 4-Chloro-2,6-diaminopyrimidine
156-83-2
|
US $0.00 / KG | 1KG | 98% | 1000KGS | Zhengzhou Anbu Chem Co.,Ltd |
-
- 4-Chloro-2,6-diaminopyrimidine
156-83-2
- US $20.00 / kg
- 99%
- hebei hongtan Biotechnology Co., Ltd
-
- 4-Chloro-2,6-diaminopyrimidine
156-83-2
- US $5.00 / kg
- ≥99%
- Jinan Finer Chemical Co., Ltd
-
- 4-Chloro-2,6-diaminopyrimidine
156-83-2
- US $0.00 / KG
- 98%
- Zhengzhou Anbu Chem Co.,Ltd
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