Angeli’s Salt
- CAS No.
- 13826-64-7
- Chemical Name:
- Angeli’s Salt
- Synonyms
- AS;Angeli Salt;ANGELI'S SALT;Angeli’s Salt;Sodium hyponitrate;Sodium oxyhyponitrite;SODIUM TRIOXODINITRATE;SODIUM ALPHA-OXYHYPONITRITE;CUVSFFFYSKZMEE-UHFFFAOYSA-N;HYPONITRIC ACID DISODIUM SALT
- CBNumber:
- CB9219704
- Molecular Formula:
- N2Na3O3+
- Molecular Weight:
- 144.98
- MDL Number:
- MFCD33404171
- MOL File:
- 13826-64-7.mol
- MSDS File:
- SDS
Density | 2.26 (monohydrate) |
---|---|
storage temp. | Store at -20°C |
solubility | H20: 50 mg/ml; PBS (pH 7.2): 50 mg/ml |
form | A crystalline solid |
FDA UNII | S8LUE47R4Z |
Angeli’s Salt price More Price(7)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 176695 | Angeli’s Salt - CAS 13826-64-7 - Calbiochem | 13826-64-7 | 10mg | $125 | 2024-03-01 | Buy |
Cayman Chemical | 82230 | Angeli’s Salt ≥99% | 13826-64-7 | 5mg | $30 | 2024-03-01 | Buy |
Cayman Chemical | 82230 | Angeli’s Salt ≥99% | 13826-64-7 | 10mg | $56 | 2024-03-01 | Buy |
Cayman Chemical | 82230 | Angeli’s Salt ≥99% | 13826-64-7 | 50mg | $225 | 2024-03-01 | Buy |
Cayman Chemical | 82230 | Angeli’s Salt ≥99% | 13826-64-7 | 100mg | $392 | 2024-03-01 | Buy |
Angeli’s Salt Chemical Properties,Uses,Production
Description
The chemical feat that perhaps best illustrates Angeli's intuitive talent was the discovery more than a century ago of the sodium salt of nitroxylaminic acid, also called Angeli's Salt (Na2N2O3). Na2[ON=NO2] is regarded as a classic nitroxyl(N=O-) donor, but under certain conditions evolution of NO is also observed. Angelo Angeli found that'salts of nitroxylaminic acid are readily resolved into the corresponding nitrites and the unsaturated nitroxyl residue. Angeli suggested their use as possible in vitro and in vivo sources of HNO,but physiological properties of this molecule didn't attract very much attention until the end of the 20th century.
Angeli's salt can be conveniently synthesized by treating hydroxylamine hydrochloride with excess sodium hydroxide,yielding hydroxylamine,which is further treated with butyl nitrate to produce the salt as a white solid.
Uses
Sodium Oxyhyponitrite is used in the treatment for hemolysis.
Uses
HNO/NO- donor in biochemical model studies.
General Description
A nitroxyl anion (NO–) donor that spontaneously dissociates in a pH dependent first order process to liberate 0.54 moles of NO per mole of the parent compound. Half-life (t?) in 100 mM phosphate buffer, pH 7.4 is 2.3 minutes at 37°C. Decomposition is nearly instantaneous at pH 5.0.
Biochem/physiol Actions
Primary TargetNitroxyl anion (NO-) donor
Angeli’s Salt Preparation Products And Raw materials
Raw materials
Preparation Products
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Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34571 | 58 |
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Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Suzhou Shanyang Pharmaceutical Technology Co., | 0512-63121618 18506119477 | 3936290802@qq.com | China | 520 | 58 |