Isobutyl acetoacetate
- CAS No.
- 7779-75-1
- Chemical Name:
- Isobutyl acetoacetate
- Synonyms
- ACIB;ISOBUTYL ACETOACETATE;Isobutyl 3-oxobutanoate;Isobutyl Acetoacetate >Isobutyl acetoacetate(IBAA);2-Methylpropyl acetoacetate;ACETOACETIC ACID ISOBUTYL ESTER;Isobutyl acetoacetate USP/EP/BP;Isobutyl Acetoacetate, 98.0%(GC);3-Oxobutyric acid isobutyl ester
- CBNumber:
- CB9234174
- Molecular Formula:
- C8H14O3
- Molecular Weight:
- 158.2
- MDL Number:
- MFCD00059349
- MOL File:
- 7779-75-1.mol
- MSDS File:
- SDS
| Melting point | 177-179 °C(Solv: ethyl ether (60-29-7)) |
|---|---|
| Boiling point | 100 °C/22 mmHg (lit.) |
| Density | 0.98 g/mL at 25 °C (lit.) |
| refractive index |
n |
| FEMA | 2177 | ISOBUTYL ACETOACETATE |
| Flash point | 173 °F |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| pka | 10?+-.0.46(Predicted) |
| form | liquid |
| color | clear |
| Odor | at 10.00 % in dipropylene glycol. sweet wine brandy fruity |
| Odor Type | fruity |
| JECFA Number | 597 |
| BRN | 1761405 |
| LogP | 1.60 |
| CAS DataBase Reference | 7779-75-1(CAS DataBase Reference) |
| Substances Added to Food (formerly EAFUS) | ISOBUTYL ACETOACETATE |
| FDA 21 CFR | 172.515 |
| FDA UNII | 5HI9DAL68Z |
| NIST Chemistry Reference | Butanoic acid, 3-oxo-, 2-methylpropyl ester(7779-75-1) |
| EPA Substance Registry System | Butanoic acid, 3-oxo-, 2-methylpropyl ester (7779-75-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H227-H315-H319 | |||||||||
| Precautionary statements | P210-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P370+P378-P403+P235-P501 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2918.30.9000 | |||||||||
| NFPA 704 |
|
Isobutyl acetoacetate price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 00483 | Isobutyl acetoacetate ≥98.0% (GC) | 7779-75-1 | 100ml | $64.3 | 2024-03-01 | Buy |
| Sigma-Aldrich | 688657 | Isobutyl acetoacetate Lonza quality, ≥97.0% (GC) | 7779-75-1 | 1kg | $101 | 2023-06-20 | Buy |
| TCI Chemical | A0814 | Isobutyl Acetoacetate >98.0%(GC) | 7779-75-1 | 25mL | $22 | 2024-03-01 | Buy |
| Sigma-Aldrich | 688657 | Isobutyl acetoacetate Lonza quality, ≥97.0% (GC) | 7779-75-1 | 180kg | $3820 | 2022-05-15 | Buy |
| TRC | I780045 | Isobutyl Acetoacetate | 7779-75-1 | 50g | $120 | 2021-12-16 | Buy |
Isobutyl acetoacetate Chemical Properties,Uses,Production
Description
Isobutyl acetoacetate has a sweet, winey, brandy-like odor and a sweet and slightly fruity flavor. May be prepared from isobutyl acetate by heating in the presence of sodium isobutylate.
Chemical Properties
Isobutyl acetoacetate has a sweet, winy, brandy-like odor and a sweet and slightly fruity flavor.
Chemical Properties
Isobutyl acetoacetate is a clear colorless liquid. Insoluble in water, soluble in alcohol and oils. B.P. approximately 196℃. The odor is somewhat fresher, not as "fermented" as that of the n-But yiester, while the taste of the iso-Butylester is somewhat less sweet. In general, the former is preferred for “winey” effects, while this (latter) is preferred for fruity effects, and partly as a fixative for the more volatile esters used in hard candy flavoring etc. Concentrations are usually around 25 ppm.
Uses
Isobutyl Acetoacetate is a building block that has been used as a reactant in the preparation of b-annulated 1,4-dihydropyridine derivatives as TGFβ signaling inhibitors.
Uses
Isobutyl acetoacetate is used as intermediate for the production of pharmaceuticals (e.g. Nisoldipine). Product Data Sheet
Definition
ChEBI: 2-Methylpropyl 3-oxobutanoate is an oxo carboxylic acid.
Preparation
From isobutyl acetate by heating in the presence of sodium isobutylate. Or by Claisen condensation of iso-ButyI acetate with Ethylacetate, using Sodium ethoxide catalyst.
Isobutyl acetoacetate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29825 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34571 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 24330 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9427 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52861 | 58 |
| LUYUNJIA CHEMISTRY XIAMEN LIMITED | +86-592-5360779 +86-13055435203 | China | 5996 | 58 | |
| Hebei Guanlang Biotechnology Co., Ltd. | +8619930503259 | cherry@crovellbio.com | China | 18430 | 58 |
View Lastest Price from Isobutyl acetoacetate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-09 | Isobutyl acetoacetate
7779-75-1
|
US $1.00 / KG | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- Isobutyl acetoacetate
7779-75-1
- US $1.00 / KG
- 99%
- Career Henan Chemical Co