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Tubulysin A,TubA

Tubulysin A,TubA Structure
Tubulysin A,TubA structure
CAS No.
205304-86-5
Chemical Name:
Tubulysin A,TubA
Synonyms
TubA;CS-1324;Tubulysin A;Tubulysins A;Tubulysin A,TubA;(2S,4R)-4-[[2-[(1R,3R)-1-acetyloxy-4-methyl-3-[3-methylbutanoyloxymethyl-[(2S,3S)-3-methyl-2-[[(2R)-1-methylpiperidine-2-carbonyl]amino]pentanoyl]amino]pentyl]-1,3-thiazole-4-carbonyl]amino]-5-(4-hydroxyphenyl)-2-methylpentanoicaci;Benzenepentanoic acid, γ-[[[2-[(1R,3R)-1-(acetyloxy)-4-methyl-3-[[(2S,3S)-3-methyl-2-[[[(2R)-1-methyl-2-piperidinyl]carbonyl]amino]-1-oxopentyl][(3-methyl-1-oxobutoxy)methyl]amino]pentyl]-4-thiazolyl]carbonyl]amino]-4-hydroxy-α-methyl-, (αS,γR)-
CBNumber:
CB92518395
Molecular Formula:
C43H65N5O10S
Molecular Weight:
844.07
MDL Number:
MFCD12912448
MOL File:
205304-86-5.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:20
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Tubulysin A,TubA Properties

Melting point 106-108 °C(Solv: methanol (67-56-1); water (7732-18-5))
Boiling point 979.9±65.0 °C(Predicted)
Density 1.195±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility organic solvents: soluble
form film
pka 4.52±0.23(Predicted)
color colorless or white
FDA UNII X9RP3ADE9Z

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301-H311-H315-H319-H331-H335
Precautionary statements  P261-P280-P301+P310-P305+P351+P338-P311
Hazard Codes  T
Risk Statements  23/24/25-36/37/38
Safety Statements  36/37-45
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3

Tubulysin A,TubA price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC T897135 TubulysinA 205304-86-5 0.25mg $385 2021-12-16 Buy
TRC T897135 TubulysinA 205304-86-5 1mg $1405 2021-12-16 Buy
TRC T897135 TubulysinA 205304-86-5 2.5mg $2805 2021-12-16 Buy
TRC T897135 TubulysinA 205304-86-5 5mg $4235 2021-12-16 Buy
American Custom Chemicals Corporation PEP0004574 TUBULYSIN A 95.00% 205304-86-5 1MG $2684.85 2021-12-16 Buy
Product number Packaging Price Buy
T897135 0.25mg $385 Buy
T897135 1mg $1405 Buy
T897135 2.5mg $2805 Buy
T897135 5mg $4235 Buy
PEP0004574 1MG $2684.85 Buy

Tubulysin A,TubA Chemical Properties,Uses,Production

Uses

Tubulysin A is a novel antibiotic, which is anti-microtubule, anti-mitotic, an apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative.

Definition

ChEBI: Tubulysin A is a diester and a carboxylic acid.

Biochem/physiol Actions

Tubulysin A is a novel antibiotic, which is anti-microtubule, anti-mitotic, apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative. Tubulysins are cytotoxic peptides, which include 9 members (A-I). Tubulysin A has potential application as an anticancer agent. It arrests cells in the G2/M phase. Tubulysin A inhibits polymerization more efficiently than vinblastine and induces depolymerization of isolated microtubules. Tubulysin A has potent cytostatic effects on various tumor cell lines with IC50 in the picomolar range.

Tubulysin A,TubA Preparation Products And Raw materials

Raw materials

Preparation Products

Tubulysin A,TubA Suppliers

Global( 52)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29811 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10473 58
ChemExpress 		+86-021-58950125 +86-021-58950125; info@chemexpress.com China 781 58
Alfa Chemistry 		Info@alfa-chemistry.com United States 24072 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054 trendseenbio@gmail.com China 11681 58
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4861 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51456 80
SPIRO PHARMA eric_feng1954@126.com China 9248 55
Zhengzhou Acme Chemical Co., Ltd. 0371-0371-55629727 13323845623 2885676761@qq.com China 9996 58
Supplier Advantage
BOC Sciences 		58
career henan chemical co 		58
Zhejiang J&C Biological Technology Co.,Limited 		58
ChemExpress 		58
Alfa Chemistry 		58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		58
MedChemexpress LLC 58
Sigma-Aldrich 80
SPIRO PHARMA 55
Zhengzhou Acme Chemical Co., Ltd. 58

View Lastest Price from Tubulysin A,TubA manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Tubulysin A,TubA pictures 2019-12-26 Tubulysin A,TubA
205304-86-5
 US $1.00 / g 1g ≥98% g/kg/Ton Career Henan Chemical Co

205304-86-5(Tubulysin A,TubA)Related Search:

2-Aminoethyl(ethyl)amine N-Ethyl-3-methylaniline N-ethyl-pyrrolidone N-(2-Hydroxyethyl)-2-pyrrolidone
TubA Tubulysin A Tubulysin A,TubA Tubulysins A CS-1324 Benzenepentanoic acid, γ-[[[2-[(1R,3R)-1-(acetyloxy)-4-methyl-3-[[(2S,3S)-3-methyl-2-[[[(2R)-1-methyl-2-piperidinyl]carbonyl]amino]-1-oxopentyl][(3-methyl-1-oxobutoxy)methyl]amino]pentyl]-4-thiazolyl]carbonyl]amino]-4-hydroxy-α-methyl-, (αS,γR)- (2S,4R)-4-[[2-[(1R,3R)-1-acetyloxy-4-methyl-3-[3-methylbutanoyloxymethyl-[(2S,3S)-3-methyl-2-[[(2R)-1-methylpiperidine-2-carbonyl]amino]pentanoyl]amino]pentyl]-1,3-thiazole-4-carbonyl]amino]-5-(4-hydroxyphenyl)-2-methylpentanoicaci 205304-86-5 C43H65N5O10S