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Ro 01-6128

Ro 01-6128 Structure
Ro 01-6128 structure
CAS No.
302841-86-7
Chemical Name:
Ro 01-6128
Synonyms
Ro 01-6128;Ro 01 6128,Ro 016128;ILSZPWZFQHSKLW-UHFFFAOYSA-N;Ethyl (2,2-diphenylacetyl)carbamate;ethyl N-[2,2-di(phenyl)acetyl]carbamate;(Diphenylacetyl)-carbamic acid ethy ester;Carbamic acid, N-(2,2-diphenylacetyl)-, ethyl ester
CBNumber:
CB92561078
Molecular Formula:
C17H17NO3
Molecular Weight:
283.32
MDL Number:
MFCD20270619
MOL File:
302841-86-7.mol
Last updated:2023-05-21 10:59:17
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Ro 01-6128 Properties

Density 1.156±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble to 100 mM in DMSO and to 100 mM in ethanol
form Powder
pka 7.97±0.46(Predicted)
FDA UNII N4LS35GV3Q

Ro 01-6128 price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 11991 Ro 01-6128 ≥98% 302841-86-7 1mg $25 2024-03-01 Buy
Cayman Chemical 11991 Ro 01-6128 ≥98% 302841-86-7 5mg $119 2024-03-01 Buy
Cayman Chemical 11991 Ro 01-6128 ≥98% 302841-86-7 10mg $225 2024-03-01 Buy
Tocris 4348 Ro01-6128 ≥98%(HPLC) 302841-86-7 10 $111 2021-12-16 Buy
Tocris 4348 Ro01-6128 ≥98%(HPLC) 302841-86-7 50 $475 2021-12-16 Buy
Product number Packaging Price Buy
11991 1mg $25 Buy
11991 5mg $119 Buy
11991 10mg $225 Buy
4348 10 $111 Buy
4348 50 $475 Buy

Ro 01-6128 Chemical Properties,Uses,Production

Description

Glutamate, the major excitatory neurotransmitter in the CNS, activates eight known subtypes of metabotropic glutamate receptors (mGluRs). Highly selective modulators designed to act at allosteric sites on certain mGluR subtypes are being developed to preferentially regulate subtype-specific, glutamate-induced receptor activation. Ro 01-6128 is a positive allosteric modulator of mGluR1 that can potentiate glutamate-induced calcium release at rat mGluR1a with an EC50 value of 104 nM. Ro 01-6128 activates ERK1/2 phosphorylation in the absence of exogenously added glutamate with an EC50 value of 248 nM and potentiates glutamate-induced cAMP production with an EC50 value of 21.5 μM.

Uses

Ro 01-6128 is an allosteric mGluR-1 activator.

Ro 01-6128 Preparation Products And Raw materials

Raw materials

Preparation Products

Ro 01-6128 Suppliers

Global( 35)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
MQ (shanghai) Pharmaceuticals Co., Ltd. 13761635123 1014988033@qq.com China 4997 55
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
JinOu Biomedical (Nanjing) Co., Ltd. 13000000000 jinoupharma@163.com China 11732 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 sales@tybiochem.com China 5449 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9154 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
EMMX Biotechnology LLC 60
MQ (shanghai) Pharmaceuticals Co., Ltd. 55
MedBioPharmaceutical Technology Inc 58
JinOu Biomedical (Nanjing) Co., Ltd. 58
TargetMol Chemicals Inc. 58
Nanjing Tengyi Biotechnology Co., Ltd 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
RD International Technology Co., Limited 58
Ro 01-6128 ILSZPWZFQHSKLW-UHFFFAOYSA-N (Diphenylacetyl)-carbamic acid ethy ester ethyl N-[2,2-di(phenyl)acetyl]carbamate Ro 01 6128,Ro 016128 Carbamic acid, N-(2,2-diphenylacetyl)-, ethyl ester Ethyl (2,2-diphenylacetyl)carbamate 302841-86-7