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EthanediaMide iMpurity F

EthanediaMide iMpurity F Structure
EthanediaMide iMpurity F structure
CAS No.
480452-37-7
Chemical Name:
EthanediaMide iMpurity F
Synonyms
Edoxaban-6;Edoxaban RC 4;Edoxaban iMpurities 6;Tropicamide Impurity 33;EthanediaMide iMpurity F;Edoxaban Impurity 3 Monomer;Edoxaban?Ethanediamide?Impurity;N-[(1S,2R,4S)-2-Amino-4-(dimethylcarbamoyl)cyclohexyl]-N'-(5-chloropyridin-2-yl)oxamide;N1-{(1S,2R,4S)-2-Amino-4-[(dimethylamino)carbonyl]cyclohexyl}-N2-(5-chloropyridin-2-yl)ethanediamide;N1-[(1S,2R,4S)-2-Amino-4-[(dimethylamino)carbonyl]cyclohexyl]-N2-(5-chloro-2-pyridinyl)ethanediamide
CBNumber:
CB92676934
Molecular Formula:
C16H22ClN5O3
Molecular Weight:
367.83
MDL Number:
MFCD30747786
MOL File:
480452-37-7.mol
Last updated:2025-04-18 09:53:05
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EthanediaMide iMpurity F Properties

Density 1.34±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
form Solid
pka 9.46±0.70(Predicted)

EthanediaMide iMpurity F price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0147989 Edoxabanimpurity6 480452-37-7 5mg $400 2021-12-16 Buy
ChemScene CS-0147989 Edoxabanimpurity6 480452-37-7 10mg $680 2021-12-16 Buy
Product number Packaging Price Buy
CS-0147989 5mg $400 Buy
CS-0147989 10mg $680 Buy

EthanediaMide iMpurity F Chemical Properties,Uses,Production

Uses

Edoxaban impurity 6 is an impurity of Edoxaban. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and can be used for stroke prevention[1][2].

References

[1] Furugohri T, et al. DU-176b, a potent and orally active factor Xa inhibitor: in vitro and in vivo pharmacological profiles. J Thromb Haemost. 2008 Sep;6(9):1542-9. DOI:10.1111/j.1538-7836.2008.03064.x
[2] Mendell J, Lee F, Chen S, The Effects of the Antiplatelet Agents, Aspirin and Naproxen, on Pharmacokinetics and Pharmacodynamics of the Anticoagulant Edoxaban, a Direct Factor Xa Inhibitor. J Cardiovasc Pharmacol. 2013 Apr 23. DOI:10.1097/FJC.0b013e3182970991

EthanediaMide iMpurity F synthesis

480452-36-6
480452-37-7
Synthesis of EthanediaMide iMpurity F from EthanediaMide iMpurity D

EthanediaMide iMpurity F Preparation Products And Raw materials

Raw materials

EthanediaMide iMpurity D N-(5-Chloropyridin-2-yl)oxalaMic acid ethyl ester tert-butyl (1R,2S,5S)-2-aMino-5-(diMethylcarbaMoyl)cyclohexylcarbaMate 2-Amino-5-chloropyridine

Preparation Products

EthanediaMide iMpurity F Suppliers

Global( 65)Suppliers
Supplier Tel Email Country ProdList Advantage
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14332 58
CR Corporation Limited 		+8613062833949 fred.wen@crcorporation.cn China 8647 58
China National Standard Pharmaceutical Corporation Limited 		+8615391658522 overseasales@yongstandards.com China 11922 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+86-18621343501; +undefined18621343501 product@acmec-e.com China 33338 58
SHANGHAI KEAN TECHNOLOGY CO., LTD. 		+8613817748580 cooperation@kean-chem.com China 40066 58
Guangzhou CATO Research Chemicals Inc. 		+86-020-81960175-617 +8615602392859 Intermediate@cato-chem.com China 6335 58
Pure Research Chemicals 		13564847951 18019592524 info@purerechem.com China 967 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
Shanghai Payne Pharmaceutical Technology Co.Ltd 		021-58123769 18678586262 info@paynepharm.com China 1354 58
QUALITY CONTROL SOLUTIONS LTD. 		0755-66853366; 13670046396 ORDERS@QCSRM.COM China 24342 58
Supplier Advantage
Standardpharm Co. Ltd. 		58
CR Corporation Limited 		58
China National Standard Pharmaceutical Corporation Limited 		58
Shanghai Acmec Biochemical Technology Co., Ltd. 		58
SHANGHAI KEAN TECHNOLOGY CO., LTD. 		58
Guangzhou CATO Research Chemicals Inc. 		58
Pure Research Chemicals 		58
Amadis Chemical Company Limited 		58
Shanghai Payne Pharmaceutical Technology Co.Ltd 		58
QUALITY CONTROL SOLUTIONS LTD. 		58

View Lastest Price from EthanediaMide iMpurity F manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N1-(5-chloropyridin-2-yl)-N2-((1S,2R,4S)-2-[(tert-Butoxycarbonyl) Amino ]-4-[(dimethylamino)carbonyl]-cyclohexyl) oxalamide dimethanesulfonate pictures 2023-09-08 N1-(5-chloropyridin-2-yl)-N2-((1S,2R,4S)-2-[(tert-Butoxycarbonyl) Amino ]-4-[(dimethylamino)carbonyl]-cyclohexyl) oxalamide dimethanesulfonate
480452-37-7
 US $0.00 / KG Ton 1KG Ton 99.5%+ 2 tons/month Zhuhai Hairuide Bioscience and Technology Co., Ltd

480452-37-7(EthanediaMide iMpurity F)Related Search:

2-(((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)amino)-2-oxoacetic acid 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride edoxaban carbamic acid, n-[(1r,2r,5s)-5-[(dimethylamino)carbonyl]-2-hydroxycyclohexyl]-, 1,1-dimethylethyl ester Ethyl 2-((5-chloropyridin-2-yl)amino)-2-oxoacetate hydrochloride
(1R,2R,4S)-2-[(tert-butoxycarbonyl)aMino]-4-[(diMethylaMino)carbonyl]cyclohexyl Methanesulfonate Thiazolo[5,4-c]pyridine, 4,5,6,7-tetrahydro-5-methyl- EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2S,4R)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]- tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate EthanediaMide, N1-(5-chlo...
EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4R)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]- (1R,3R,4R)-3-AMino-4-hydroxy-cyclohexanecarboxylic acid ethyl ester (1S,3S,4S)-3-AMino-4-hydroxy-cyclohexanecarboxylic acid ethyl ester 2-Amino-6-chloropyridine EthanediaMide, N1-(5-chlo...
EthanediaMide, N1-(5-chlo... (1S,3R,4S)-4-(2-((5-chloropyridin- 2-yl)amino)-2-oxoacetamido)-3-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexane-1-carboxylic acid 2-Amino-3-chloropyridine

1of4

N1-(5-chloropyridin-2-yl)-N2-((1S,2R,4S)-2-[(tert-Butoxycarbonyl)Amino ]-4-[(dimethylamino)carbonyl]-cyclohexyl) oxalamide dimethanesulfonate EthanediaMide iMpurity F N1-{(1S,2R,4S)-2-Amino-4-[(dimethylamino)carbonyl]cyclohexyl}-N2-(5-chloropyridin-2-yl)ethanediamide Edoxaban-6 Edoxaban impurity 14/N1-(5-chloropyridin-2-yl)-N2-((1S,2R,4S)-2-[(tert-Butoxy carbonyl)Amino]-4-[(dimethylamino)carbonyl]-cyclohexyl) oxalamide dimethanesulfonate Edoxaban iMpurities 6 Ethanediamide, N1-[(1S,2R,4S)-2-amino-4-[(dimethylamino)carbonyl]cyclohexyl]-N2-(5-chloro-2-pyridinyl)- N1-((1S,2R,4S)-2-Amino-4-(dimethylcarbamoyl)cyclohexyl)-N2-(5-chloropyridin-2-yl)oxalamide (Edoxaban Impurity) Edoxaban RC 4 Edoxaban Impurity 54Q: What is Edoxaban Impurity 54 Q: What is the CAS Number of Edoxaban Impurity 54 Edoxaban Impurity 3 Monomer Tropicamide Impurity 33 N1-[(1S,2R,4S)-2-Amino-4-[(dimethylamino)carbonyl]cyclohexyl]-N2-(5-chloro-2-pyridinyl)ethanediamide Edoxaban?Ethanediamide?Impurity N-[(1S,2R,4S)-2-Amino-4-(dimethylcarbamoyl)cyclohexyl]-N'-(5-chloropyridin-2-yl)oxamide 480452-37-7 C16H22ClN5O3