Diphenylvinylsulfonium Triflate
- CAS No.
- 247129-88-0
- Chemical Name:
- Diphenylvinylsulfonium Triflate
- Synonyms
- Diphenyl(vinyl)sulfonium trifluoromethanesulfonate;Diphenylvinylsulfonium triflate;ethenyl(diphenyl)sulfanium;Sulfonium hanesulfonate (1:1);ethenyldiphenylsulfanium trifluoromethanesulfonate;SulfoniuM, ethenyldiphenyl-, 1,1,1-trifluoroMethanesulfonate;SulfoniuM, ethenyldiphenyl-, 1,1,1-trifluoroMethanesulfonate (1:1)
- CBNumber:
- CB92704802
- Molecular Formula:
- C15H13F3O3S2
- Molecular Weight:
- 362.38
- MDL Number:
- MFCD22123284
- MOL File:
- 247129-88-0.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
Diphenylvinylsulfonium Triflate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth Carbosynth | FD146166 | Diphenylvinylsulfonium triflate | 247129-88-0 | 25mg | $50 | 2021-12-16 | Buy |
| Synthonix | D6369 | DiphenylvinylsulfoniumTriflate 97.0% | 247129-88-0 | 1g | $80 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD146166 | Diphenylvinylsulfonium triflate | 247129-88-0 | 50mg | $80 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD146166 | Diphenylvinylsulfonium triflate | 247129-88-0 | 100mg | $125 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD146166 | Diphenylvinylsulfonium triflate | 247129-88-0 | 500mg | $300 | 2021-12-16 | Buy |
Diphenylvinylsulfonium Triflate Chemical Properties,Uses,Production
Description
Diphenylvinylsulfonium Triflate is a pale yellow, oily organic compound. It has a vinylsulfonium salt structure, and nucleophiles readily undergo conjugate addition reactions with vinylsulfonium salts to form thionimide intermediates, which can undergo a series of further transformations. Applications in epoxidation, azide and other cyclisation reactions have demonstrated the broad applicability of vinyl sulfonium salts as two-carbon bridges.
Uses
Diphenylvinylsulfonium Triflate can be used as GLP-??1r modulating compounds to treat GLP-??1R mediated diseases such as metabolic and related diseases, including but not limited to NASH, obesity, and type 2 diabetes.
Synthesis
Diphenylvinylsulfonium Triflate is synthesised using (2-bromoethyl)diphenylsulfonium trifluoromethanesulfonate as a raw material by chemical reaction. The specific synthesis steps are as follows:
INTERMEDIATE 75(DiphenylXvmyDsulfonium trifluoromethanesulfonateIntermediate 74 (11.4 g, 25.7 mmol) was dissolved in THF/H2O (2:1) (42 mL). KHCO3 (3.1 g, 30.9 mmol) was added and the reaction mixture was stirred for 20 minutes at r.t. The solvent was evaporated immediately under reduced pressure (using a rotary evaporator connected to a high vacuum pump and keeping the water-bath temperature below 2O0C). The reaction mixture was then redissolved in DCM (40 mL), dried over MgSO4, filtered and evaporated. The residue was redissolved in DCM (10 mL) and loaded onto a silica bed (4 cm depth and 2.5 cm diameter). The resulting band was covered with 1 cm sand and eluted with DCM (400 mL), followed by 10% MeOH in DCM (200 mL). The product was isolated as a light brown oil (9.53 g, quantitative). 6H (CDCl3) 7.90-7.87 (4H, m), 7.79-7.66 (6H, m), 7.53 (IH, dd, J 8.8, 8.8 Hz), 6.69 (IH, dd, J 9.5, 2.5 Hz), 6.55 (IH, dd, J 16.5, 2.5 Hz).
Diphenylvinylsulfonium Triflate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 17777 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | bess@weibangbio.com | China | 18150 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57505 | 58 |
| Suzhou ARTK Medchem Co., Ltd. | +86-512-68323658 +86-18168183658 | sales1@artkmedchem.com | China | 39004 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Chengdu Feibo Pharm Technology Co., Ltd | +86 028-84641798 15982321820 | abby@arkpharm.com | China | 10923 | 58 |