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2-MERCAPTO-5-METHOXYBENZIMIDAZOLE

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE structure

CAS No.: 37052-78-1

Chemical Name:: 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE

Synonyms: 5-METHOXY-1H-BENZO[D]IMIDAZOLE-2-THIOL;Omeprazole Impurity A;OMeprazole Related CoMpound B;5-METHOXY-2-BENZIMIDAZOLETHIOL;5-METHOXY-2-MERCAPTOBENZIMIDAZOLE;5-methoxy-1H-benzoimidazole-2-thiol;H 118/87;5-Methoxy;OMEP IM-A;TIMTEC-BB SBB000219

CBNumber:: CB9313620

Molecular Formula:: C8H8N2OS

Molecular Weight:: 180.23

MDL Number:: MFCD00134581

MOL File:: 37052-78-1.mol

MSDS File:: SDS

Last updated:2024-08-21 22:41:43

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2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Properties

Melting point	261-263 °C(lit.)
Boiling point	309.4±44.0 °C(Predicted)
Density	1.2425 (rough estimate)
vapor pressure	0.001Pa at 25℃
refractive index	1.5690 (estimate)
storage temp.	2-8°C
solubility	DMSO (Slightly), Methanol (Sparingly)
pka	10.13±0.30(Predicted)
form	Powder
color	Off-white to light yellow-brown
Water Solubility	insoluble
Sensitive	Air Sensitive
BRN	3605123
LogP	1.52-2.399
CAS DataBase Reference	37052-78-1(CAS DataBase Reference)
FDA UNII	143562LXX0

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

Hazard Codes

Risk Statements

Safety Statements

WGK Germany

HazardClass

IRRITANT

HS Code

29332900

NFPA 704

	1
2		0

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE price More Price(34)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	382485	5-Methoxy-2-benzimidazolethiol 99%	37052-78-1	5g	$52.7	2024-03-01	Buy
Sigma-Aldrich	1478480	Omeprazole Related Compound B United States Pharmacopeia (USP) Reference Standard	37052-78-1	15mg	$1380	2024-03-01	Buy
TCI Chemical	M1256	2-Mercapto-5-methoxybenzimidazole >98.0%(HPLC)(T)	37052-78-1	25g	$90	2024-03-01	Buy
Alfa Aesar	B20570	2-Mercapto-5-methoxybenzimidazole, 99%	37052-78-1	5g	$26.65	2024-03-01	Buy
Alfa Aesar	B20570	2-Mercapto-5-methoxybenzimidazole, 99%	37052-78-1	25g	$94.3	2023-06-20	Buy

Product number	Packaging	Price	Buy
382485	5g	$52.7	Buy
1478480	15mg	$1380	Buy
M1256	25g	$90	Buy
B20570	5g	$26.65	Buy
B20570	25g	$94.3	Buy

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Chemical Properties,Uses,Production

Description

2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2[[(4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl] sulfonyl]-1H-benzimidazole, 5-methoxy-2[[(4-methoxy-3, 5-dimethylpyridin-2-yl-1-oxide) methyl] sulfonyl]-1H-benzimidazole as well as tris[μ-1,2-bis(diphenylphosphino)ethane]-1:2κ2P:P′;1:3κ2P:P′;2:3κ2P:P′-di-μ-bromido-1:2κ4Br:Br-bromido-3κBr-tricopper(I) acetone hemisolvate. Furthermore, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole1. Finally, it acts as an intermediate for manufacture of the anti-ulcer drug Omeprazole.

Chemical Properties

off-white to light yellowish-brown powder

Uses

5-Methoxy-2-benzimidazolethiol may be used in the preparation of compounds present as contaminants in omeprazole, such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. It may be used in the synthesis of tris[μ-1,2-bis(diphenylphosphino)ethane]-1:2κ²P:P′;1:3κ²P:P′;2:3κ²P:P′-di-μ-bromido-1:2κ⁴Br:Br-bromido-3κBr-tricopper(I) acetone hemisolvate.

Uses

Reagent used in the synthesis of COX-2 inhibitors

Uses

2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. Further, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole.

General Description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Flammability and Explosibility

Not classified

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

Ufiprazole Omeprazole 2-[(5-methoxy-1H-benzimidazol-2-yl)sulfanyl]-N-(2-nitrophenyl)acetamide

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Suppliers

Global( 773)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Weibang Biotechnology Co., Ltd	+8615531157085	abby@weibangbio.com	China	8810	58
Hebei Mojin Biotechnology Co., Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12839	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5892	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	973	58
Hebei Saisier Technology Co., LTD	+86-18400010335 +86-18034520335	admin@hbsaisier.cn	China	1015	58
Hebei Longbang Technology Co., LTD	+86-18633929156 +86-18633929156	admin@hblongbang.com	China	941	58
HebeiShuoshengImportandExportco.,Ltd	+86-18532138899 +86-18532138899	L18532138899@163.com	China	939	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29791	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	18774	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55

Supplier	Advantage
Hebei Weibang Biotechnology Co., Ltd	58
Hebei Mojin Biotechnology Co., Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Anhui Ruihan Technology Co., Ltd	58
Hebei Saisier Technology Co., LTD	58
Hebei Longbang Technology Co., LTD	58
HebeiShuoshengImportandExportco.,Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55

View Lastest Price from 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-11-29	2-MERCAPTO-5-METHOXYBENZIMIDAZOLE 37052-78-1	US $10.00 / KG	1KG	99%	10 mt	Hebei Weibang Biotechnology Co., Ltd
2024-11-29	5-Methoxy-2-mercaptobenzimidazole 37052-78-1	US $0.00 / Kg/Drum	1ASSAYS	99%	50mt	Jinan Finer Chemical Co., Ltd
2024-11-29	2-MERCAPTO-5-METHOXYBENZIMIDAZOLE 37052-78-1	US $6.00 / KG	1KG	99%	20TONS	Hebei Longbang Technology Co., Ltd

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE
37052-78-1
US $10.00 / KG
99%
Hebei Weibang Biotechnology Co., Ltd

5-Methoxy-2-mercaptobenzimidazole
37052-78-1
US $0.00 / Kg/Drum
99%
Jinan Finer Chemical Co., Ltd

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE
37052-78-1
US $6.00 / KG
99%
Hebei Longbang Technology Co., Ltd

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Spectrum

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE(37052-78-1)MS 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE(37052-78-1)¹HNMR 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE(37052-78-1)¹³CNMR 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE(37052-78-1)IR1 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE(37052-78-1)IR2 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE(37052-78-1)Raman

37052-78-1(2-MERCAPTO-5-METHOXYBENZIMIDAZOLE)Related Search:

2-Ethylhexyl mercaptoacetate Mercaptoacetic acid 2-Mercaptobenzimidazole 2-Methoxyethanol Benzimidazole

2-Methylbenzimidazole 3-Mercaptopropionic acid Ufiprazole OMEPRAZOLE RELATED COMPOUND A (15 MG) (OMEPRAZOLE SULFONE) (AS) Calcium thioglycolate

Omeprazole 5-METHOXY-2-[((4-METHOXY-3,5-DIMETHYL-1-OXIDO-2-PYRIDINYL)METHYL)SULFINYL]-BENZIMIDAZOLE Esomeprazole Impurity 3 (S)-4-Desmethoxy-4-chloro Omeprazole 4-Hydroxy Omeprazole

Omeprazole EP Impurity F Omeprazole Sulfone N-Oxide EsoMeprazole related substance H431/41

1of4

5-Methoxye-2-mercaplobenzinidazole TIMTEC-BB SBB000219 5-Methoxybenzimidazole-2-thiol 5-METHOXY-2-THIOBENZIMIDAZOLE 2-MERCAPTO-5-METHOXY-1H-BENZIMIDAZOLE 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE 1,3-DIHYDRO-5-METHOXY-2H-BENZIMIDAZOLE-2-THIONE LABOTEST-BB LT01596137 H 118/87 5-methoxy-2(1H)-benzimidazolinethione 2-Mercato-5-methoxy benzimidazole 5-METHOXY-2-THIOHYDROXYBENZIMIDAZOLE(INTERMEDIATE OF OMEPRAZOLE) 2-Mercapto-5-MethoxyBenzimidazole(ForOmeprazole) 5-METHOXY-2-BENZIMIDAZOLEETHIOL 2-Mercapto-5-methoxy-1H-benzim 5-methoxy-2-thiohydroxy benzimidazole 5-Methoxy-2-thiobenzimidazole 99% 2H-Benzimidazole-2-thione,1,3-dihydro-5-methoxy-(9CI) 5-METHOXY-2-MERCAPTOBENIMIDAZOLEOMEPRAZOLE 5-METHOXYL-2-MERCAPTOBENZIMIDAZOLE 5-Methoxy-1H-1,3-benzodiazole-2-thiol 5-Methoxy-1,3-dihydrobenzimidazole-2-thione 5-Methoxy-2-benzimidazolethiol ,99% 5-METHOXY-2-MERCAPTOBENZIMIDAZOLE, 99+% 6-Methoxy-1H-benzimidazole-2-thiol 6-Methoxy-2-mercapto-1H-benzimidazole 5-Methoxy-2-mercapto 5-Methoxy-1H-benzimidazole-2-thiol 99% (S)-Omeprazole Intermediate 2 Omeprazole EP impurity-A (USP RC B) Esomeprazole impurity A Omeprazole Imp. A(EP)(USP RC B): (5-Methoxy-1H-Benzimidazole-2-Thiol) 2-mercapto-5-methyoxy benzimidazole (omeprazole-benzimidazole) 5-DIFLUOROMETHOXY-2-MERCAPTO- BENZIMIDZO LE Omeprazole RCB (USP) EsoMeprazole related substance A EsoMeprazol iMpurity A OMeprazole IMpurity-A (EP) OMeprazole EP IMpurity A 5-Methoxy-1H-benzimidazole-2-thiol, 2-Mercapto-5-methoxy-1H-benzimidazole 5-Methoxy-2-thio-1H-benzimidazole 99% 5-Methoxy-1H-benzo[d]iMidazole-2(3H)-thione OMeprazole IMpurity A (5-Methoxy-1H-BenziMidazole-2-Thiol) 5-Methoxy-1H-benzo[d]iMidazole-2-thiol (RelCpd A) 2H-BenziMidazole-2-thione, 1,3-dihydro-5-Methoxy- 2-Mercatto-5-Methoxy-1H-BenziMidazde 5-Methoxy-2-benziMidazolethiol 99% 5-Methoxy-2-mercaptobenzimidazole 5-Methoxybenzimidazole-2-thiol 5-Methoxy-2-mercaptobenzimidazole 5-Methoxy-2-benzimidazolethiol Esomeprazole Magnesium Trihydrate Imp. A (EP): 5-Methoxy-1H-benzimidazole-2-thiol Esomeprazole EP Impurity A 2-Mercapoto-5-Methoxy-1H-benzimidazole Esomeprazole Sodium Impurity Ⅴ:5-Methoxy-2-mercaptobenzimidazole 5-Methoxy 5-Methoxy-2-thio-1H-benzimidazole Esomeprazol EP Impurity A(Omeprazole EP Impurity A) 2-MERCAPTO -5-METHOXY BENZIMIDAZOLE (METOXITIONA ) OMEP IM-A