ANTI-DYSTROPHIN
- CAS No.
- Chemical Name:
- ANTI-DYSTROPHIN
- Synonyms
- ANTI-DYSTROPHIN;ANTI-DYSTROPHIN, MID-ROD;ANTI-DYSTROPHIN (ROD DOMAIN);ANTI-DYSTROPHIN (N-TERMINUS);ANTI-DYSTROPHIN (C-TERMINUS);Anti-DMD antibody produced in rabbit;Anti-Dystrophin antibody produced in rabbit;Monoclonal Anti-Dystrophin antibody produced in mouse
- CBNumber:
- CB9313761
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00164586
- MOL File:
- Mol file
ANTI-DYSTROPHIN price More Price(8)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SAB1408565 | Anti-DMD antibody produced in rabbit purified immunoglobulin, buffered aqueous solution | 100μg | $524 | 2024-03-01 | Buy | |
Sigma-Aldrich | HPA023885 | Anti-DMD antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $547 | 2024-03-01 | Buy | |
Sigma-Aldrich | HPA002725 | Anti-DMD antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $547 | 2024-03-01 | Buy | |
Sigma-Aldrich | D8168 | Monoclonal Anti-Dystrophin antibody produced in mouse clone MANDYS8, ascites fluid | 100μL | $360 | 2024-03-01 | Buy | |
Sigma-Aldrich | D8168 | Monoclonal Anti-Dystrophin antibody produced in mouse clone MANDYS8, ascites fluid | 0.2mL | $559 | 2024-03-01 | Buy |
ANTI-DYSTROPHIN Chemical Properties,Uses,Production
Uses
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Western Blotting (1 paper)
Uses
Monoclonal Anti-Dystrophin antibody produced in mouse has been used in
- immunohistochemistry
- immunofluorescence
- double immunofluorescence terminal dUTP nick-end labeling (TUNEL)
- immunoblotting
General Description
Monoclonal Anti-Dystrophin (mouse IgG2b isotype) is derived from the MANDYS8 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. Dystrophin is a structural protein on the inner face of the membrane, consisting of a 25-repeat, rod-like, triple-helical domain separating an N-terminal actin binding domain from two C-terminal domains, one of which is rich in cysteine.
Biochem/physiol Actions
In striated muscle cells, DMD (dystrophin) acts as a component of the multimeric protein dystrophin-associated glycoprotein (DGC) complex. It helps DGC to adhere with the extracellular matrix for various signalling pathways. It helps to maintain structural assembly of plasma membrane, regulates ion homeostasis and transmembrane signaling cascade. It stabilzes muscle fiber cells. It is associated with various muscular dystrophies, such as Duchenne/Becker muscular dystrophy, congenital muscular dystrophy and different forms of limb-girdle muscular dystrophy.
ANTI-DYSTROPHIN Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-DYSTROPHIN Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Supplier | Advantage |
---|---|
Sigma-Aldrich | 80 |