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MRT-83 hydrochloride

MRT-83 hydrochloride structure

CAS No.: 1359944-60-7

Chemical Name:: MRT-83 hydrochloride

Synonyms: MRT-83 HCl salt;MRT-83 hydrochloride

CBNumber:: CB93313504

Molecular Formula:: C31H31ClN4O5

Molecular Weight:: 575.06

MDL Number:

MOL File:: 1359944-60-7.mol

Last updated:2024-10-23 13:36:13

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MRT-83 hydrochloride Properties

storage temp.	4°C, away from moisture
solubility	DMSO : 250 mg/mL (434.74 mM; Need ultrasonic)
form	Solid
color	White to off-white

MRT-83 hydrochloride Chemical Properties,Uses,Production

Biological Activity

MRT-83 (hydrochloride) is the potent antagonist of Smoothened (Smo) receptor. MRT-83 (hydrochloride) inhibits the Hedgehog (Hh) signaling pathway and BODIPY-cyclopamine binding to human Smo. MRT-83 (hydrochloride) has the potential for researching cancer disease[1]. MRT-83 (hydrochloride) (compound 86) has IC50s of 15 and 11 nM respectively in Shh-light2 and C3H10T1/2 cells in the biological activity assay[1].

References

[1]. Solinas A, et al. Acylthiourea, acylurea, and acylguanidine derivatives with potent hedgehog inhibiting activity. J Med Chem. 2012;55(4):1559-1571.

MRT-83 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

MRT-83 hydrochloride Suppliers

Global( 6)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.		support@targetmol.com	United States	38463	58
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9806	58
Beijing Solarbio Science & Tecnology Co., Ltd.	010-50973130 4009686088	3193328036@qq.com	China	29785	68
Changzhou Furuisi Biotechnology Co., Ltd	0519-85524369	3477467573@qq.com	China	8617	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24648	58
Suzhou Zhixin Biotechnology Co., Ltd.	0512-65118909 15162312715	sales@szzxbio.com	China	2991	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Shanghai EFE Biological Technology Co., Ltd.	58
Beijing Solarbio Science & Tecnology Co., Ltd.	68
Changzhou Furuisi Biotechnology Co., Ltd	58
TargetMol Chemicals Inc.	58
Suzhou Zhixin Biotechnology Co., Ltd.	58

View Lastest Price from MRT-83 hydrochloride manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-10-24	MRT-83 hydrochloride 1359944-60-7	US $82.00 / mg			10g	TargetMol Chemicals Inc.

MRT-83 hydrochloride
1359944-60-7
US $82.00 / mg
TargetMol Chemicals Inc.

MRT-83 hydrochloride MRT-83 HCl salt 1359944-60-7