Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>sodium:(E,3R,5S)-7-[4-(4-fluorophenyl)-6-(1,1,1,3,3,3-hexadeuteriopropan-2-yl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate

sodium:(E,3R,5S)-7-[4-(4-fluorophenyl)-6-(1,1,1,3,3,3-hexadeuteriopropan-2-yl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate

sodium:(E,3R,5S)-7-[4-(4-fluorophenyl)-6-(1,1,1,3,3,3-hexadeuteriopropan-2-yl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate Structure
sodium:(E,3R,5S)-7-[4-(4-fluorophenyl)-6-(1,1,1,3,3,3-hexadeuteriopropan-2-yl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate structure
CAS No.
2070009-41-3
Chemical Name:
sodium:(E,3R,5S)-7-[4-(4-fluorophenyl)-6-(1,1,1,3,3,3-hexadeuteriopropan-2-yl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate
Synonyms
Antipyrine Impurity 15;Rosuvastatin Sodium Salt-D6;(3R,5S,E)-7-(4-(4-fluorophenyl)-2-(N-methylmethylsulfonamido)-6-(propan-2-yl-1,1,1,3,3,3-d6)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate,monosodiumsalt;sodium:(E,3R,5S)-7-[4-(4-fluorophenyl)-6-(1,1,1,3,3,3-hexadeuteriopropan-2-yl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate;Rosuvastatin Sodium D6Q: What is Rosuvastatin Sodium D6 Q: What is the CAS Number of Rosuvastatin Sodium D6 Q: What is the storage condition of Rosuvastatin Sodium D6 Q: What are the applications of Rosuvastatin Sodium D6
CBNumber:
CB93400796
Molecular Formula:
C22H29FN3NaO6S
Molecular Weight:
505.54
MDL Number:
MFCD28900701
MOL File:
2070009-41-3.mol
Last updated:2023-06-08 09:03:09
Request For Quotation

sodium:(E,3R,5S)-7-[4-(4-fluorophenyl)-6-(1,1,1,3,3,3-hexadeuteriopropan-2-yl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate Properties

storage temp. Store at 4°C
solubility Methanol: Soluble
form A solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
NFPA 704
0
2 0

sodium:(E,3R,5S)-7-[4-(4-fluorophenyl)-6-(1,1,1,3,3,3-hexadeuteriopropan-2-yl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 23359 Rosuvastatin-d6 (sodium salt) ≥98% 2070009-41-3 500μg $231 2024-03-01 Buy
Cayman Chemical 23359 Rosuvastatin-d6 (sodium salt) ≥98% 2070009-41-3 1mg $414 2024-03-01 Buy
Cayman Chemical 23359 Rosuvastatin-d6 (sodium salt) ≥98% 2070009-41-3 5mg $1468 2024-03-01 Buy
AK Scientific 5853DV Rosuvastatin(D6Sodium) 2070009-41-3 1mg $559 2021-12-16 Buy
Product number Packaging Price Buy
23359 500μg $231 Buy
23359 1mg $414 Buy
23359 5mg $1468 Buy
5853DV 1mg $559 Buy

sodium:(E,3R,5S)-7-[4-(4-fluorophenyl)-6-(1,1,1,3,3,3-hexadeuteriopropan-2-yl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate Chemical Properties,Uses,Production

Biological Activity

Rosuvastatin-d6 is intended for use as an internal standard for the quantification of rosuvastatin by GC- or LC-MS. Rosuvastatin is an HMG-CoA reductase inhibitor (IC50 = 5 nM).1,2 It is a fully-synthetic inhibitor that is designed to maximize the points of contact with, and inhibition of, HMG-CoA reductase.1 Formulations containing rosuvastatin reduce low-density lipoprotein and C-reactive protein and increase high-density lipoprotein in humans.3,4

References

1.Istvan, E.S., and Deisenhofer, J.Structural mechanism for statin inhibition of HMG-CoA reductaseScience292(5519)1160-1164(2001) 2.Tobert, J.A.Lovastatin and beyond: The history of the HMG-CoA reductase inhibitorsNat. Rev. Drug Discov.2(7)517-526(2003) 3.Asztalos, B.F., Maulf, F.L., Dallal, G.E., et al.Comparison of the effects of high doses of Rosuvastatin versus Atorvastatin on the subpopulations of high-density lipoproteinsAm. J. Cardiol.99(5)681-685(2007) 4.Rubba, P., Marotta, G., and Gentile, M.Efficacy and safety of rosuvastatin in the management of dyslipidemiaVasc. Health Risk Manag.5(1)343-352(2009)

sodium:(E,3R,5S)-7-[4-(4-fluorophenyl)-6-(1,1,1,3,3,3-hexadeuteriopropan-2-yl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate Preparation Products And Raw materials

Raw materials

Preparation Products

sodium:(E,3R,5S)-7-[4-(4-fluorophenyl)-6-(1,1,1,3,3,3-hexadeuteriopropan-2-yl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate Suppliers

Global( 15)Suppliers
Supplier Tel Email Country ProdList Advantage
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9707 58
Hefei Molake Biotechnology Co., Ltd. 0551-66336380 18956014586 983438788@qq.com China 2115 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Cato Research Chemicals Inc. 020-81215950 4000-868-328 customer@uwalab.com United States 10413 58
InvivoChem 13549236410 sales@invivochem.cn China 6755 58
Cato Research Chemicals Inc. 020-81960175-877 18933936954 tianwen.zhan@cato-chem.com China 7735 58
Shanghai Beiwanta Biotechnology Co., Ltd. 021-67187366 19901745723 info@bwtlab.com China 9257 58
guoyungurui 18162595016 3287908757@qq.com China 10338 58
Nanjing Shizhou Biology Technology Co.,Ltd 17301488900 judy.xia@synzest.com China 12582 58
Supplier Advantage
InvivoChem 		58
Shanghai EFE Biological Technology Co., Ltd. 58
Hefei Molake Biotechnology Co., Ltd. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Cato Research Chemicals Inc. 58
InvivoChem 58
Cato Research Chemicals Inc. 58
Shanghai Beiwanta Biotechnology Co., Ltd. 58
guoyungurui 58
Nanjing Shizhou Biology Technology Co.,Ltd 58

2070009-41-3(sodium:(E,3R,5S)-7-[4-(4-fluorophenyl)-6-(1,1,1,3,3,3-hexadeuteriopropan-2-yl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate)Related Search:

3-Oxo Rosuvastatin SodiuM Salt N-Desmethyl Rosuvastatin Lactone tert-butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate (4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester Rosuvastatin ethyl ester
Rosuvastatin Impurity 91 Rosuvastatin Related Compound 8 Rosuvastatin Calcium Salt tert-Butyl 2-((4S,6S)-6-(chloromethyl(02,2-1,3-dioxan-4-yl)acetate NGABCYSYENPREI-RYUDHWBXSA-N
4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidine-5-carboxylic acid Rosuvastatin EP Impurity C Rosuvastatin EP impurity H Desfluoro Rosuvastatin Sodium Salt 5-PyriMidinecarboxylic acid, 4-(4-fluorophenyl)-1,2-dihydro-6-(1-Methylethyl)-2-oxo-, Methyl ester
Phosphonium, [[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]me Ethyl propionylacetate Rosuvastatin Impurity 4

1of4

sodium:(E,3R,5S)-7-[4-(4-fluorophenyl)-6-(1,1,1,3,3,3-hexadeuteriopropan-2-yl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate (3R,5S,E)-7-(4-(4-fluorophenyl)-2-(N-methylmethylsulfonamido)-6-(propan-2-yl-1,1,1,3,3,3-d6)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate,monosodiumsalt Rosuvastatin Sodium D6Q: What is Rosuvastatin Sodium D6 Q: What is the CAS Number of Rosuvastatin Sodium D6 Q: What is the storage condition of Rosuvastatin Sodium D6 Q: What are the applications of Rosuvastatin Sodium D6 Rosuvastatin Sodium Salt-D6 Antipyrine Impurity 15 2070009-41-3