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ChemicalBook >> CAS DataBase List >>3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid

3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid

3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid Structure
3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid structure
CAS No.
683808-78-8
Chemical Name:
3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid
Synonyms
Poloppin;Poloppin >=98% (HPLC);1H-Pyrrole-2-propanoic acid, 5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-;3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid
CBNumber:
CB93698449
Molecular Formula:
C20H15BrF3NO2
Molecular Weight:
438.2378096
MDL Number:
MFCD03706653
MOL File:
683808-78-8.mol
Last updated:2023-03-31 09:12:58
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3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid Properties

Boiling point 536.7±50.0 °C(Predicted)
Density 1.45±0.1 g/cm3(Predicted)
pka 4.62±0.10(Predicted)

3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML2186 Poloppin ≥98% (HPLC) 683808-78-8 5MG $81.3 2024-03-01 Buy
Sigma-Aldrich SML2186 Poloppin ≥98% (HPLC) 683808-78-8 25MG $411 2024-03-01 Buy
ChemScene CS-0087610 Poloppin 683808-78-8 5mg $200 2021-12-16 Buy
ChemScene CS-0087610 Poloppin 683808-78-8 10mg $340 2021-12-16 Buy
Product number Packaging Price Buy
SML2186 5MG $81.3 Buy
SML2186 25MG $411 Buy
CS-0087610 5mg $200 Buy
CS-0087610 10mg $340 Buy

3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid Chemical Properties,Uses,Production

Description

Poloppin is a modulator of protein-protein interactions of the mitotic polo-like kinases. It acts by targeting mutant KRAS, working synergistically with Crizotinib, an inhibitor of the c-MET receptor, against mutant KRAS-expressing cancer cells.

3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid Suppliers

Global( 9)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32760 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9708 58
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 info@SuperLan-chem.com China 9874 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369 3477467573@qq.com China 8618 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
TargetMol Chemicals Inc. 		58
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai Chaolan Chemical Technology Center 58
Shanghai Hongye Biotechnology Co. Ltd 58
Energy Chemical 58
Changzhou Furuisi Biotechnology Co., Ltd 58
TargetMol Chemicals Inc. 58
3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid Poloppin Poloppin >=98% (HPLC) 1H-Pyrrole-2-propanoic acid, 5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]- 683808-78-8