DEXCHLORPHENIRAMINE
- CAS No.
- 25523-97-1
- Chemical Name:
- DEXCHLORPHENIRAMINE
- Synonyms
- C06946;fortamine;isomerine;chlo-amine;phendextro;Mylaramine;S-Chlorpheniramine;d-chlorpheniramine;exchlorpheniramine;DEXCHLORPHENIRAMINE
- CBNumber:
- CB9399974
- Molecular Formula:
- C16H19ClN2
- Molecular Weight:
- 274.79
- MDL Number:
- MFCD00865695
- MOL File:
- 25523-97-1.mol
alpha | D25 +49.8° (c = 1 in DMF) |
---|---|
Boiling point | 142 °C(Press: 1.0 Torr) |
Density | 1.107±0.06 g/cm3(Predicted) |
pka | 9.33±0.28(Predicted) |
FDA UNII | 3Q9Q0B929N |
ATC code | R06AB02,R06AB52 |
DEXCHLORPHENIRAMINE price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
American Custom Chemicals Corporation | API0006290 | (+)-CHLORPHENIRAMINE 95.00% | 25523-97-1 | 1G | $668.5 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0006290 | (+)-CHLORPHENIRAMINE 95.00% | 25523-97-1 | 5G | $898.31 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0006290 | (+)-CHLORPHENIRAMINE 95.00% | 25523-97-1 | 10G | $1280.79 | 2021-12-16 | Buy |
DEXCHLORPHENIRAMINE Chemical Properties,Uses,Production
Originator
Polaramine,Schering,US,1958
Uses
Activity of this drug is approximately twice that of chlorpheniramine. Dexchlorpheniramine is also used for allergy symptoms, rhinitis, and dermatitis.
Uses
Antihistaminic.
Definition
ChEBI: Dexchlorpheniramine is a chlorphenamine. It is an enantiomer of a levochlorpheniramine.
Manufacturing Process
Twenty grams of d-phenylsuccinic acid and 28 grams of 3-(2-pyridyl)-3-pchlorophenyl-N,N-dimethylpropylamine are dissolved in 400 ml of absolute
ethyl alcohol and allowed to stand at room temperature until crystallization is
effected. The crystals are filtered, washed with absolute ethyl alcohol and
recrystallized from 300 ml of this solvent in the same manner. The crystals
are recrystallized twice from 80% ethyl alcohol using 3.5 ml per gram of
compound in the manner described above and pure d-3-(2-pyridyl)-3-pchlorophenyl-N,Ndimethylpropylamine-d-phenylsuccinate is obtained, melting
point 145-147°C.
This salt is shaken with 100 ml of diethyl ether and 50 ml of 20% aqueous
potassium carbonate; the ether layer is separated, dried over anhydrous
potassium carbonate, filtered and the ether is removed in vacuo. The d-3-(2-
pyridyl)-3-p-chlorophenyl-N,N-dimethylpropylamine so obtained is a mobile
oil.
4.3 grams of the above base and 1.8 grams of maleic acid are dissolved in 20
ml isopropyl acetate and kept at room temperature until crystallization is
complete. The crystals are filtered, washed with ethyl acetate and
recrystallized from 15 ml of this solvent in the same manner. The crystalline
d-3-(2-pyridyl)-3-p-chlorophenyl-N,N-dimethylpropylamine maleate so formed
is then filtered off and dried. MP 113-115°C from US Patent 3,030,371.
brand name
Mylaramine (Morton Grove); Polaramine (Schering).
Therapeutic Function
Antihistaminic
DEXCHLORPHENIRAMINE Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
DEXCHLORPHENIRAMINE Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5867 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 8853 | 58 |
Shanghai Hekang Biotechnology Co., Ltd. | 18939837085 | youchemicals@gmail.com | China | 1829 | 55 |
HX Pharmaceutical technology co., LTD | 15671363360 | 494267389@qq.com | China | 2856 | 58 |
Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 4579 | 58 |
Hubei YuanCheng Pharmaceutical Co., Ltd. | 18062666904 | wyy01@ycphar.com | China | 669 | 65 |
View Lastest Price from DEXCHLORPHENIRAMINE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-08-20 | Chlorpheniramine maleate
25523-97-1
|
US $10.50-10.50 / KG | 1KG | 99 | 1 ton | Hebei Chuanghai Biotechnology Co,.LTD |
- Chlorpheniramine maleate
25523-97-1
- US $10.50-10.50 / KG
- 99
- Hebei Chuanghai Biotechnology Co,.LTD