ANTI-GX/Z ALPHA (GX/ZALPHA)
- CAS No.
- Chemical Name:
- ANTI-GX/Z ALPHA (GX/ZALPHA)
- Synonyms
- ANTI-GX/Z ALPHA (GX/ZALPHA);ANTI-GX/Z-ALPHA-SUBUNIT (AB-7), MAMMALIAN;Anti-Gαx/z antibody produced in rabbit
- CBNumber:
- CB9417364
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01092353
- MOL File:
- Mol file
ANTI-GX/Z ALPHA (GX/ZALPHA) price More Price(1)
ANTI-GX/Z ALPHA (GX/ZALPHA) Chemical Properties,Uses,Production
Uses
Anti-Gαx/z antibody produced in rabbit is suitable for western blot analysis at a working dilution of 1:100-1:200 using plasma membrane fractions.
General Description
G-proteins are membrane associated heterotrimeric proteins that are comprised of α-, β-, and γ-subunits. These proteins play a key role in signal transduction pathways that regulate cell′s response to several hormones, neuromodulators and ligands. The αz subunit is myristoylated near the N-terminus.
Biochem/physiol Actions
The gene GNAZ (guanine nucleotide binding protein (G protein), αz polypeptide) encodes an α subunit of guanine nucleotide binding proteins. The α-subunit contains a guanine-binding domain that is in its inactive state when it is occupied by GDP. Upon activation, GDP is replaced with GTP, causing the dissociation of the α-subunit from the βγ-subunit complex. This enables the Gα-GTP complex to bind to and regulate specific signaling pathways. GTP is then hydrolyzed, allowing for re-association of the α-subunit with the βγ-subunit complex. When coupled to phospholipase C, the α subunits may have a role in pertussis toxin-insensitive pathways.
ANTI-GX/Z ALPHA (GX/ZALPHA) Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-GX/Z ALPHA (GX/ZALPHA) Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Riedel-de Haen AG | -- | United States | 6825 | 87 | |
SIGMA-RBI | -- | Switzerland | 6913 | 91 | |
EMD Biosciences, Inc. | -- | technical@calbiochem.com | United States | 6529 | 66 |
Supplier | Advantage |
---|---|
Riedel-de Haen AG | 87 |
SIGMA-RBI | 91 |
EMD Biosciences, Inc. | 66 |