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ANTI-GX/Z ALPHA (GX/ZALPHA)

ANTI-GX/Z ALPHA (GX/ZALPHA) Structure
ANTI-GX/Z ALPHA (GX/ZALPHA) structure
CAS No.
Chemical Name:
ANTI-GX/Z ALPHA (GX/ZALPHA)
Synonyms
ANTI-GX/Z ALPHA (GX/ZALPHA);ANTI-GX/Z-ALPHA-SUBUNIT (AB-7), MAMMALIAN;Anti-Gαx/z antibody produced in rabbit
CBNumber:
CB9417364
Molecular Formula:
Molecular Weight:
0
MDL Number:
MFCD01092353
MOL File:
Mol file
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ANTI-GX/Z ALPHA (GX/ZALPHA) Properties

storage temp. −20°C

SAFETY

Risk and Safety Statements

WGK Germany  -

ANTI-GX/Z ALPHA (GX/ZALPHA) price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich G5165 Anti-Gαx/z antibody produced in rabbit whole antiserum 0.1ml $288 2023-01-07 Buy
Product number Packaging Price Buy
G5165 0.1ml $288 Buy

ANTI-GX/Z ALPHA (GX/ZALPHA) Chemical Properties,Uses,Production

Uses

Anti-Gαx/z antibody produced in rabbit is suitable for western blot analysis at a working dilution of 1:100-1:200 using plasma membrane fractions.

General Description

G-proteins are membrane associated heterotrimeric proteins that are comprised of α-, β-, and γ-subunits. These proteins play a key role in signal transduction pathways that regulate cell′s response to several hormones, neuromodulators and ligands. The αz subunit is myristoylated near the N-terminus.

Biochem/physiol Actions

The gene GNAZ (guanine nucleotide binding protein (G protein), αz polypeptide) encodes an α subunit of guanine nucleotide binding proteins. The α-subunit contains a guanine-binding domain that is in its inactive state when it is occupied by GDP. Upon activation, GDP is replaced with GTP, causing the dissociation of the α-subunit from the βγ-subunit complex. This enables the Gα-GTP complex to bind to and regulate specific signaling pathways. GTP is then hydrolyzed, allowing for re-association of the α-subunit with the βγ-subunit complex. When coupled to phospholipase C, the α subunits may have a role in pertussis toxin-insensitive pathways.

ANTI-GX/Z ALPHA (GX/ZALPHA) Preparation Products And Raw materials

Raw materials

Preparation Products

ANTI-GX/Z ALPHA (GX/ZALPHA) Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
Riedel-de Haen AG -- United States 6825 87
SIGMA-RBI -- Switzerland 6913 91
EMD Biosciences, Inc. -- technical@calbiochem.com United States 6529 66
Supplier Advantage
Riedel-de Haen AG 87
SIGMA-RBI 91
EMD Biosciences, Inc. 66
ANTI-GX/Z ALPHA (GX/ZALPHA) ANTI-GX/Z-ALPHA-SUBUNIT (AB-7), MAMMALIAN Anti-Gαx/z antibody produced in rabbit Alphabetical Index Antibodies to G Proteins and Cyclic Nucleotides Antibodies to G ProteinsAntibodies Cell Biology G