POLYOXIN A
- CAS No.
- 19396-03-3
- Chemical Name:
- POLYOXIN A
- Synonyms
- POLYOXIN A;POLYOXIN A USP/EP/BP;monocarbamate(ester),(e)-l-noyl)-3-ethylidene;2-azetidinecarboxylicacid,1-(5-(2-amino-2-deoxy-l-xylonamido)-1,5-dideoxy-1-(;3,4-dihydro-5-(hydroxymethyl)-2,4-dioxo-1(2h)-pyrimidinyl)-beta-d-allofuranuro;1-(5-(2-amino-2-deoxy-l-xylonamido)-1,5-dideoxy-1-(3,4-dihydro-5-(hydroxymethyl)-2,4-dioxo-1(2h)-pyr2-azetidinecarboxylic aci;2-Azetidinecarboxylic acid, 1-[5-[[2-amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-1,5-dideoxy-1-[3,4-dihydro-5-(hydroxymethyl)-2,4-dioxo-1(2H)-pyrimidinyl]-β-D-allofuranuronoyl]-3-ethylidene-, (2S,3Z)-
- CBNumber:
- CB9479290
- Molecular Formula:
- C23H32N6O14
- Molecular Weight:
- 616.53
- MDL Number:
- MFCD01665292
- MOL File:
- 19396-03-3.mol
| alpha | D20 -30° |
|---|---|
| Density | 1.748±0.06 g/cm3(Predicted) |
| pka | 3.07±0.20(Predicted) |
| FDA UNII | FGY211ZGNZ |
SAFETY
Risk and Safety Statements
| Toxicity | Acute oral LD50>20000mg/kg in rats and mice, acute transdermal LD50>12000mg/kg in rats, acute inhalation LD50 in rats >10mg/L. No irritation to rabbit eyes and skin. No carcinogenic, teratogenic or mutagenic effects were found in animal experiments. Carp LC50>40mg/L (48h), Daphnia LC50>40mg/L (3h). Low toxicity to bees, LD50>1000mg/bee. |
|---|
POLYOXIN A Chemical Properties,Uses,Production
Chemical Properties
Colorless needle crystal, m.p.180°C or amorphous crystal, m.p.160°C (decomposition). POLYOXIN A is easily soluble in water, but insoluble in organic solvents such as methanol, ethanol, acetone, chloroform, benzene and ether. It is stable to ultraviolet light, acidic solution and neutral solution, unstable to alkaline solution, and stable for more than 3 years when stored at room temperature. The appearance of the industrial product is light brown powder or taupe powder.
Uses
POLYOXIN A is a broad-spectrum antibiotic fungicide with systemic conduction. It is mainly used to control wheat powdery mildew, ginseng black spot, tobacco red spot, cucumber downy mildew, melon wilt, rice sheath blight, apple spotted leaf spot, strawberry and grape gray mold, forest sheath wilt, etc.
Synthesis
POLYOXIN A can be obtained by the method: connect the sand pipe to the slope (aseptic operation) and cultivate it at a constant temperature of 28°C. After the spores grow and mature, connect the slope spores to the slope again. After constant temperature cultivation, it will be the slope for production; tank), fermentation (fermentation tank), acidification, concentration, spray drying and crushing.
POLYOXIN A Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
POLYOXIN A Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17365 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 7724 | 58 |
| Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +86-18791163155 +86-13119157289 | 13119157289@163.com | China | 2973 | 58 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14055 | 65 |
| Zhejiang Huida Biotech Co., LTD | 0571-89903882 13626641628 | jiangnan@huidabiotech.com | China | 3656 | 58 |
| Zhejiang Huida Biotech Co., LTD | 0571-0571-89903882 15990081639 | sunshixuan@huidabiotech.com | China | 3705 | 58 |
| Supplier | Advantage |
|---|---|
| SIMAGCHEM CORP | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 58 |
| Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | 58 |
| BOC Sciences | 65 |
| Zhejiang Huida Biotech Co., LTD | 58 |
| Zhejiang Huida Biotech Co., LTD | 58 |