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Cyclosporin A-Derivative 1 Free base

CAS No.
286852-20-8
Chemical Name:
Cyclosporin A-Derivative 1 Free base
Synonyms
Cyclosporin A-Derivative 1 Free base;N-Methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-;Glycine, N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-, methyl ester
CBNumber:
CB94844681
Molecular Formula:
C65H117N11O14
Molecular Weight:
1276.69
MDL Number:
MFCD31814419
MOL File:
286852-20-8.mol
Last updated:2023-05-29 08:28:42

Cyclosporin A-Derivative 1 Free base Properties

Boiling point 1225.9±65.0 °C(Predicted)
Density 1.093±0.06 g/cm3(Predicted)
solubility DCM, Methanol
form Solid
pka 13.07±0.46(Predicted)
color Off-White

Cyclosporin A-Derivative 1 Free base price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M315685 N-Methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycineMethylEster 286852-20-8 25mg $140 2021-12-16 Buy
Biorbyt Ltd orb573305 Cyclosporin A-Derivative 1 Free base >98% 286852-20-8 100mg $1431.4 2021-12-16 Buy
Biorbyt Ltd orb573305 Cyclosporin A-Derivative 1 Free base >98% 286852-20-8 250mg $2839 2021-12-16 Buy
Biorbyt Ltd orb573305 Cyclosporin A-Derivative 1 Free base >98% 286852-20-8 1g $5654.2 2021-12-16 Buy
DC Chemicals DC20101 CyclosporinA-Derivative1Freebase >98% 286852-20-8 100mg $950 2021-12-16 Buy
Product number Packaging Price Buy
M315685 25mg $140 Buy
orb573305 100mg $1431.4 Buy
orb573305 250mg $2839 Buy
orb573305 1g $5654.2 Buy
DC20101 100mg $950 Buy

Cyclosporin A-Derivative 1 Free base Chemical Properties,Uses,Production

Uses

N-Methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine Methyl Ester is an intermediate in the synthesis of Cyclosporin AM 4N (C989410), a metabolite of Cyclosporin A (C988900). Cyclosporin A is a hydrophobic cyclic undecapeptide that is used as a potent immunosuppressive agent that has application in human organ transplantation. Cyclosporin A works by inhibiting subsets of T lymphocytes to facilitate organ transplantation.

83602-41-9
286852-20-8
Synthesis of Cyclosporin A-Derivative 1 Free base from SDZ 33-243

Cyclosporin A-Derivative 1 Free base Preparation Products And Raw materials

Raw materials

Preparation Products

Cyclosporin A-Derivative 1 Free base Suppliers

Global( 7)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences
16314854226; +16314854226 inquiry@bocsci.com United States 19743 58
Creative Peptides info@creative-peptides.com United States 6084 56
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9412 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29778 58
Cyclosporin A-Derivative 1 Free base N-Methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl- Glycine, N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-, methyl ester 286852-20-8