Cyclosporin A-Derivative 1 Free base

286852-20-8

CAS番号.: 286852-20-8

化学名:

别名:

英語名:: Cyclosporin A-Derivative 1 Free base

英語别名:: Cyclosporin A-Derivative 1 Free base;N-Methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-;Glycine, N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-, methyl ester

CBNumber:: CB94844681

化学式:: C65H117N11O14

分子量:: 1276.69

MOL File:: 286852-20-8.mol

物理性質

安全性情報

用途語

生産企業 7

Cyclosporin A-Derivative 1 Free base 物理性質

沸点 :: 1225.9±65.0 °C(Predicted)

比重(密度) :: 1.093±0.06 g/cm3(Predicted)

溶解性:: DCM、メタノール

外見 :: 個体

酸解離定数(Pka):: 13.07±0.46(Predicted)

色:: オフホワイト

安全性情報

Cyclosporin A-Derivative 1 Free base 価格

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入

Cyclosporin A-Derivative 1 Free base 化学特性,用途語,生産方法

使用

N-Methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine Methyl Ester is an intermediate in the synthesis of Cyclosporin AM 4N (C989410), a metabolite of Cyclosporin A (C988900). Cyclosporin A is a hydrophobic cyclic undecapeptide that is used as a potent immunosuppressive agent that has application in human organ transplantation. Cyclosporin A works by inhibiting subsets of T lymphocytes to facilitate organ transplantation.

Cyclosporin A-Derivative 1 Free base 上流と下流の製品情報

原材料

(3R,4R)-3-アセトキシ-N-メチル-5-[(E)-1-プロペニル]-シクロ(L-Leu-L-Abu-Sar-N-メチル-L-Leu-L-Val-N-メチル-L-Leu-L-Ala-D-Ala-N-メチル-L-Leu-N-メチル-L-Leu-N-メチル-L-Val-) メタノールトリメチルオキソニウムテトラフルオロボラート

準備製品

Cyclosporin A-Derivative 1 Free base 生産企業

Global( 7)Suppliers

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BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19743	58
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DC Chemicals	021-58447131 13564518121	sales@dcchemicals.com	China	9412	58
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44941	58
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840 15801484223;	psaitong@jm-bio.com	China	29778	58

286852-20-8
Cyclosporin A-Derivative 1 Free base
N-Methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-
Glycine, N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-, methyl ester