ChemicalBook >> CAS DataBase List >>inh-02
(RNF5 inhibitor inh-02)
inh-02 (RNF5 inhibitor inh-02)
- CAS No.
- 324579-65-9
- Chemical Name:
- inh-02 (RNF5 inhibitor inh-02)
- Synonyms
- RNF5-IN-2;RNF5 inhibitor Inh-2;RNF5 inhibitor inh-02;inh-02 (RNF5 inhibitor inh-02);RNF-5 inhibitor inh-02,RNF5 inhibitor inh02,RNF5 inhibitor inh 02;(E)-N-((Z)-4-benzyl-3-methyl-1,2,4-thiadiazol-5(4H)-ylidene)-N"-phenylbenzimidamide;Benzenecarboximidamide, N-[3-methyl-4-(phenylmethyl)-1,2,4-thiadiazol-5(4H)-ylidene]-N'-phenyl-;RNF5 inhibitor Inh-2 (E)-N-((Z)-4-benzyl-3-methyl-1,2,4-thiadiazol-5(4H)-ylidene)-N'-phenylbenzimidamide
- CBNumber:
- CB94844904
- Molecular Formula:
- C23H20N4S
- Molecular Weight:
- 384.5
- MDL Number:
- MFCD01849637
- MOL File:
- 324579-65-9.mol
Last updated:2024-07-02 08:55:42
inh-02 (RNF5 inhibitor inh-02) Chemical Properties,Uses,Production
Biological Activity
RNF5 inhibitor inh-02 is a potent inhibitor of E3 ubiquitin ligase RNF5/RMA1. RNF5 inhibitor inh-02 leads to significant F508del-CFTR rescue (EC50=2.2 uM) in bronchial epithelial cells homozygous for the F508del mutation. RNF5 inhibitor inh-02 can be used for cystic fibrosis research[1].
References
[1]. Elvira Sondo, et al. Pharmacological Inhibition of the Ubiquitin Ligase RNF5 Rescues F508del-CFTR in Cystic Fibrosis Airway Epithelia. Cell Chem Biol. 2018 Jul 19;25(7):891-905.e8.
inh-02 (RNF5 inhibitor inh-02) Preparation Products And Raw materials
Raw materials
Preparation Products
inh-02 (RNF5 inhibitor inh-02) Suppliers
Global( 11)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 | 757984502@qq.com | China | 892 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9707 | 58 |
| DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9412 | 58 |
| ShangHai ChuanQian Chemcial Technique Centre | 15869524721 | 3525679403@qq.com | China | 3616 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8618 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24017 | 58 |
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | 024-024-88590548 18341751992 | 757984502@qq.com | China | 892 | 58 |
| Nanjing Tengyi Biotechnology Co., Ltd | 025-58851786 17714337195 | sales@tybiochem.com | China | 5595 | 58 |
| ZhengZhou Edward Biology Co.,Ltd | 13298105281 13298105281 | 1522334715@qq.com | China | 7515 | 58 |
| Nantong Hanfang Biotechnology Co. , Ltd. | 18616537568 | hanfangpharma@126.com | China | 30968 | 58 |
inh-02
(RNF5 inhibitor inh-02)
Benzenecarboximidamide, N-[3-methyl-4-(phenylmethyl)-1,2,4-thiadiazol-5(4H)-ylidene]-N'-phenyl-
RNF5 inhibitor Inh-2
RNF5 inhibitor Inh-2 (E)-N-((Z)-4-benzyl-3-methyl-1,2,4-thiadiazol-5(4H)-ylidene)-N'-phenylbenzimidamide
RNF5 inhibitor inh-02
RNF-5 inhibitor inh-02,RNF5 inhibitor inh02,RNF5 inhibitor inh 02
(E)-N-((Z)-4-benzyl-3-methyl-1,2,4-thiadiazol-5(4H)-ylidene)-N"-phenylbenzimidamide
RNF5-IN-2
324579-65-9